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Springer Protocols eBook Series

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  • NLR Proteins

    Methods and Protocols

    Edited by Pablo Pelegrín, Francesco Di Virgilio ...
    Series series Springer Protocols
    This second edition provides a sound basis for the molecular investigation of NLR function in health and disease. Chapters focus on NLR as innate immune receptors, “atypical” inflammasomes, biochemical and novel bioluminescence techniques for the measurement of IL-1b as readout of NLR-based inflammasomes, bioluminescent probe, biochemical and microscopy techniques, techniques to measure caspase-1 ... Read more

    $134.09 USD

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  • Antibody Engineering Volume 1

    Edited by Roland E. Kontermann, Stefan Dübel ...
    Series series Springer Protocols
    Antibodies are indispensable tools for research, diagnosis, and therapy. Recombinant approaches allow the modification and improvement of nearly all antibody properties, such as affinity, valency, specificity, stability, serum half-life, effector functions, and immunogenicity. "Antibody Engineering" provides a comprehensive toolbox covering the well-established basics but also many exciting new ... Read more

    $332.09 USD

  • Handbook of Glycomics

    Edited by Richard D. Cummings, J. Michael Pierce ...
    The Handbook of Glycomics provides the first comprehensive overview of the emerging field of glycomics, defined as the study of all complex carbohydrates in an organism or cell ("the glycome"). Beginning with analytic approaches and bioinformatics, this work provides a detailed discussion of relevant databases, data integration, and analysis. It then moves on to a discussion of specific model ... Read more

    $90.89 USD

  • Tumor Organoids

    Edited by Shay Soker, Aleksander Skardal ...
    Series series Cancer Drug Discovery and Development
    Cancer cell biology research in general, and anti-cancer drug development specifically, still relies on standard cell culture techniques that place the cells in an unnatural environment. As a consequence, growing tumor cells in plastic dishes places a selective pressure that substantially alters their original molecular and phenotypic properties.The emerging field of regenerative medicine has ... Read more

    $143.09 USD

  • Translational Medicine

    Molecular Pharmacology and Drug Discovery

    Edited by Robert A. Meyers ...
    Series series Advances in Molecular Biology and Medicine
    This reference work gives a compete overview of the different stages of drug development using a translational approach. The book is structured in different parts, following the different stages in drug development. Almost half of the work is dedicated to core of drug discovery using a translational approach, the identification of appropriate targets and screening methods for the identification of ... Read more

    $382.00 USD

  • Essential Ion Channel Methods

    Edited by P. Michael Conn ...
    Series series Reliable Lab Solutions
    The rapid growth of interest and research activity in ion channels is indicative of their fundamental importance in the maintenance of the living state. This volume was prepared with a view toward providing a sampling of the range of molecular and physical methods that are significant for the study of ion channels. As part of the Reliable Lab Solutions series, Essential Ion Channel Methods brings ... Read more

    $70.19 USD

  • In Vitro Bioassay Techniques for Anticancer Drug Discovery and Development

    by Dhanya Sunil, Raghu Chandrashekhar H, Pooja Kamath ...
    This comprehensive and useful handbook represents a definitive up-to-date compendium of key in vitro bioassay methods that are employed to quantify and validate the anticancer activity of a drug candidate before it makes its way in to animal or clinical trials.In Vitro Bioassay Techniques for Anticancer Drug Discovery and Development covers the screening and evaluation of potential drug candidates ... Read more

    Was $63.99 USD Now $54.99 USD

  • HDAC/HAT Function Assessment and Inhibitor Development

    Methods and Protocols

    Edited by Oliver H. Krämer ...
    Series series Springer Protocols
    This fully updated edition provides a series of methods for how best to assess functions of histone deacetylases and acetyltransferases. The disease-relevance of dysregulated protein deacetylation by overexpressed or aberrantly activated histone deacetylases has spurred an intense search for novel and improved inhibitors of these enzymes, as reflected in this collection. Expert contributors ... Read more

    $170.09 USD

  • The P2X7 Receptor

    Methods and Protocols

    Edited by Annette Nicke ...
    Series series Springer Protocols
    This detailed volume covers diverse aspects of P2X7 receptor analysis, ranging from its molecular structure to related pharmacological and immunological tools, via its analysis in heterologous expression systems as well as assays using primary cells and whole animal models. After three introductory chapters that focus on its structure, ligands, and physiological functions, the book details the ... Read more

    $143.99 USD

  • Peroxisomes

    Methods and Protocols

    Edited by Michael Schrader ...
    Series series Springer Protocols
    This fully updated volume assembles a comprehensive collection of methods, techniques, and strategies to investigate the molecular and cellular biology of peroxisomes in different organisms. Peroxisome research is on the rise, as novel functions and proteins of this dynamic organelle are still being discovered through studies in model systems including humans, mice, flies, plants, fungi, and yeast ... Read more

    $197.99 USD

  • Pyroptosis

    Methods and Protocols

    Edited by Susan L. Fink ...
    Series series Springer Protocols
    This volume explores techniques used to study and understand the latest research on pyroptosis. The chapters in this book cover topics such as experimental methods to induce pyroptosis via inflammasomes; approaches to identifying inflammasome activation in humans; ways to induce and detect pore formation; and techniques to evaluate cellular outcomes of pyroptotic cell death. Written in the highly ... Read more

    $143.99 USD

  • MicroRNA Profiling

    Methods and Protocols

    Edited by Sweta Rani ...
    Series series Springer Protocols
    This second edition provides updated and comprehensive methods on miRNA biogenesis and their role in the development and progression of various human diseases. Chapters detail miRNA biogenesis, isolating RNA, extracellular vesicles (EVs), circulating miRNAs, analyzing miRNA and miRDeep-P2, protocols for total RNA isolation from cells, cell-derived products, isolation and characterization of ... Read more

    $116.09 USD