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  • Organelle Contact Sites

    From Molecular Mechanism to Disease

    Edición de Thomas Simmen, Mitsuo Tagaya ...
    Series series Biomedical and Life Sciences (R0)
    This book provides the first comprehensive coverage of the quickly evolving research field of membrane contact sites (MCS). A total of 16 chapters explain their organization and role and unveil the significance of MCS for various diseases.MCS, the intracellular structures where organellar membranes come in close contact with one another, mediate the exchange of proteins, lipids, and ions. Via ... Leer más

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  • Introduction to Molecular Medicine

    How will increased understanding of the human genome affect our ability to diagnose and treat disease? The subject of recombinant DNA technology is no longer limited to the research laboratory; it is being discussed in ever-widening medical circles. Introduction to Molecular Medicine is especially written for the physician who is not a genetics expert but wishes to understand this new science and ... Leer más

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  • Molecular Basis of Multiple Sclerosis

    The Immune System

    Series series Biomedical and Life Sciences (R0)
    Despite major efforts by the scientific community over the years, our understanding of the pathogenesis or the mechanisms of injury of multiple sclerosis is still limited. Consequently, the current strategies for treatment and management of patients are limited in their efficacy. The mechanisms of tissue protection and repair are probably even less understood. One reason for these limitations is ... Leer más

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  • Mechanical Stretch and Cytokines

    Edición de Andre Kamkin, Irina Kiseleva ...
    Series series Biomedical and Life Sciences (R0)
    This book presents the latest findings in the field of investigation of molecular mechanisms of mechanical stretch and the role of cytokines in response of different tissues to it. On the one hand this Volume demonstrates how mechanical stretch enhances cytokines production. It describes how cytokines influence tissues and cells on a background of a mechanical stretching. It provides a description ... Leer más

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  • Semaphorins

    A Diversity of Emerging Physiological and Pathological Activities

    Edición de Atsushi Kumanogoh ...
    Series series Biomedical and Life Sciences (R0)
    This book presents the current concepts of semaphorin biology. In the early 1990s, semaphorins were originally identified as axon guidance cues that function during neuronal development. However, cumulative findings have clarified that they have diverse functions in many physiological processes, including cardiogenesis, angiogenesis, vasculogenesis, osteoclastogenesis, retinal homeostasis, and ... Leer más

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  • microRNA: Medical Evidence

    From Molecular Biology to Clinical Practice

    Edición de Gaetano Santulli ...
    Series series Biomedical and Life Sciences (R0)
    This volume explores microRNA function in a wide array of human disorders, providing a clinical basis for precision medicine and personalized therapies using these molecules. The twenty-one chapters, all authored by internationally-renowned experts, open with an introduction contextualizing microRNA manipulation within today’s initiatives towards precision medicine. The following chapters explore ... Leer más

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  • Immuno Systems Biology

    A macroscopic approach for immune cell signaling

    Series series Biomedical and Life Sciences (R0)
    Immuno Systems Biology aims to study the immune system in the more integrated manner on how cells and molecules participate at different system levels to the immune function. Through this book Kumar Selvarajoo introduces to physicists, chemists, computer scientists, biologists and immunologists the idea of an integrated approach to the understanding of mammalian immune system. Geared towards a ... Leer más

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  • MFG-E8 and Inflammation

    Edición de Ping Wang ...
    Series series Biomedical and Life Sciences (R0)
    After the discovery of milk fat globule-epidermal growth factor-factor 8 (MFG-E8) about two decades ago, a new era of delineating its potential beneficial role in several inflammatory diseases has begun to spout from the bench to translational research. In MFG-E8 and Inflammation, the editor and contributors have gathered a remarkable collection covering novel discoveries on the rapidly growing ... Leer más

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  • Molecular and Cellular Biology of Platelet Formation

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    Edición de Harald Schulze, Joseph Italiano ...
    This book gives a comprehensive insight into platelet biogenesis, platelet signal transduction, involvement of platelets in disease, the use of diverse animal models for platelet research and future perspectives in regard to platelet production and gene therapy. Being written by international experts, the book is a concise state-of-the art work in the field of platelet biogenesis, biology and ... Leer más

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  • Recent Advances in the Pathophysiology of COPD

    Series series Medicine (R0)
    Chronic obstructive pulmonary disease (COPD) ranges amongst the commonest diseases in the world. The relentless progression of the disease causes a pressing need for a better understanding of and therapies for COPD. This volume provides state-of-the-art information on the pathophysiology of COPD including an outlook on new therapies. It is of interest to researchers and clinicians in academia as ... Leer más

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  • Interleukin-10 in Health and Disease

    Edición de Anne O'Garra, Simon Fillatreau ...
    Series series Biomedical and Life Sciences (R0)
    This volume provides a set of reviews dedicated to the biology of Interleukin (IL)-10. It includes chapters on its importance for maintaining immune homeostasis in humans, its role in intestinal immunity and its functions during viral and bacterial infections. In addition, it presents reviews on the mechanisms linking innate microbial recognition to the production of IL-10 and on how IL-10 ... Leer más

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