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1 - 12 de 12 resultados para “tapas kumar kundu”
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  • Metabolism and Epigenetic Regulation: Implications in Cancer

    Edición de Tapas Kumar Kundu, Chandrima Das ...
    Series series Biomedical and Life Sciences (R0)
    Metabolic programs of individuals are key determinants for disease susceptibility and immune response. This book, edited by experts in the field, summarizes epigenetic signaling pathways that regulate metabolic programs associated with cancer and cancer-related secondary diseases.The first part of the book highlights key metabolic pathways that are implicated in cancer and provides a comprehensive ... Leer más

    $251.99 USD

  • Epigenetics: Development and Disease

    Edición de Tapas Kumar Kundu ...
    Series series Biomedical and Life Sciences (R0)
    Epigenetics is the phenomenon which fine tunes the processes associated with life, beyond that which is specified by the sequence of the genetic material; DNA. The covalent modification of DNA, DNA associated histones, several non histone proteins as well as non coding RNA coherently operate to establish the epigenetic regulation of gene expression in physiological and pathophysiological ... Leer más

    $287.99 USD

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  • The Inhibitor Index

    A Desk Reference on Enzyme Inhibitors, Receptor Antagonists, Drugs, Toxins, Poisons, Biologics, and Therapeutic Leads

    de Daniel Purich ...
    Metabolic inhibitors and receptor antagonists are indispensable tools for the molecular life scientist. By blocking specific enzymes or receptor-mediated signal transduction cascades, they simplify the analysis of complex cellular processes especially when it is essential to demonstrate that a process of interest is functionally linked to a particular enzyme or receptor. From antibiotics to ... Leer más

    $325.99 USD

  • DNA Repair of Cancer Stem Cells

    Edición de Elain Hurt, Stephanie M Cabarcas, Lesley A Mathews ...
    Series series Biomedical and Life Sciences (R0)
    The existence of ‘cancer stem cells’ (CSCs) has been a topic of heated debate for the last few years within the field of cancer biology. Their continuous characterization in a variety of solid tumors has lead to an abundance of evidence supporting their existence. CSCs are believed to be responsible for resistance against conventional treatment regimes of chemotherapy and radiation, ultimately, ... Leer más

    $143.99 USD

  • Pharmacogenomics of Human Drug Transporters

    Clinical Impacts

    de Toshihisa Ishikawa, Richard B. Kim, Jörg König ...
    Sets the foundation for safer, more effective drug therapiesWith this book as their guide, readers will discover how to apply our current understanding of the pharmacogenomics of drug transporters to advance their own drug discovery and development efforts. In particular, the book explains how new findings in the field now enable researchers to more accurately predict drug interactions and adverse ... Leer más

    $148.00 USD

  • Autophagy in tumor and tumor microenvironment

    Edición de Sujit Kumar Bhutia ...
    Series series Biomedical and Life Sciences (R0)
    This book deals with the paradoxical role of autophagy in tumor suppression and tumor promotion in cancer cells. Autophagy plays opposing, context-dependent roles in tumors; accordingly, strategies based on inhibiting or stimulating autophagy could offer as potential cancer therapies.The book elucidates the physiological role of autophagy in modulating cancer metastasis, which is the primary cause ... Leer más

    $89.99 USD

  • Histone Deacetylase Inhibitors in Combinatorial Anticancer Therapy

    de Shabir Ahmad Ganai ...
    Series series Biomedical and Life Sciences (R0)
    This book reviews the latest developments in the design, synthesis, and molecular mechanism of action of Histone Deacetylase (HDAC) inhibitors in the context of potential cancer therapy. HDAC inhibitors are emerging as promising anticancer drug molecules that promote growth arrest, differentiation and apoptosis of cancer cells with tumor selective toxicity.The book begins with an overview of ... Leer más

    $143.99 USD

  • Long Non-coding RNAs in Human Disease

    Edición de Kevin V. Morris ...
    Series series Biomedical and Life Sciences (R0)
    This volume focuses on the roles of long non-coding RNAs (lncRNAs) in contexts ranging from human cancers to cardiovascular disease and ageing. The role of lncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, past retroelements integrated within the human genome, as well as the role these pseudogene-derived lncRNAs play in cancer development are discussed in detail. Further, the ... Leer más

    $89.99 USD

  • Histone Deacetylases: the Biology and Clinical Implication

    Edición de Tso-Pang Yao, Edward Seto ...
    Series series Biomedical and Life Sciences (R0)
    The book highlights work from many different labs that taught us abnormal HDACs potentially contribute to the development or progression of many human diseases including immune dysfunctions, heart disease, cancer, memory impairment, aging, and metabolic disorders. ... Leer más

    $287.99 USD

  • Epigenetic Therapy of Cancer

    Preclinical Models and Treatment Approaches

    Edición de Michael Lübbert, Peter A. Jones ...
    Series series Medicine (R0)
    The growing knowledge about disturbances of epigenetic gene regulation in hematopoietic stem cell disorders is now being translated into treatment approaches that target the epigenetic defects pharmacologically. This book first presents the latest evidence regarding the epigenetic regulation of hematopoietic stem cell differentiation and hemoglobin production. The significance of DNA methylation ... Leer más

    $89.99 USD

  • SUMO Regulation of Cellular Processes

    Edición de Van G. Wilson ...
    Series series Biomedical and Life Sciences (R0)
    This is the second edition of a very well received book that details how the sumoylation system functions and how it modulates numerous cellular activities. SUMO is a post-translational modifier in the ubiquitin super-family that has gained recognition over the last twenty years as an essential and prevalent regulatory molecule.Individual chapters explore the biochemistry, molecular biology, and ... Leer más

    $170.99 USD

  • Targeting Autophagy in Cancer Therapy

    Edición de Jin-Ming Yang ...
    Series series Medicine (R0)
    This volume will detail the current state and perspectives of autophagy-based cancer therapy. Covering a wide range of topics, it will include an overview of autophagy as a therapeutic target in cancer, autophagy modulators as cancer therapeutic agents, implications of micro-RNA-regulated autophagy in cancer therapy, modulation of autophagy through targeting PI3 kinase in cancer therapy, targeting ... Leer más

    $89.99 USD