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  • Statistical Bioinformatics with R

    Statistical Bioinformatics provides a balanced treatment of statistical theory in the context of bioinformatics applications. Designed for a one or two semester senior undergraduate or graduate bioinformatics course, the text takes a broad view of the subject – not just gene expression and sequence analysis, but a careful balance of statistical theory in the context of bioinformatics applications. ... Leer más

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  • Synaptic Self

    How Our Brains Become Who We Are

    de Joseph LeDoux ...
    In 1996 Joseph LeDoux's The Emotional Brain presented a revelatory examination of the biological bases of our emotions and memories. Now, the world-renowned expert on the brain has produced with a groundbreaking work that tells a more profound story: how the little spaces between the neurons—the brain's synapses—are the channels through which we think, act, imagine, feel, and remember. Synapses ... Leer más

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  • Psychiatry, Psychoanalysis, and the New Biology of Mind

    Brought together for the first time in a single volume, these eight important and fascinating essays by Nobel Prize-winning psychiatrist Eric Kandel provide a breakthrough perspective on how biology has influenced modern psychiatric thought. Complete with commentaries by experts in the field, Psychiatry, Psychoanalysis, and the New Biology of Mind reflects the author's evolving view of how biology ... Leer más

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  • The Birth of the Mind

    How a Tiny Number of Genes Creates The Complexities of Human Thought

    de Gary Marcus ...
    In The Birth of the Mind , award-winning cognitive scientist Gary Marcus irrevocably alters the nature vs. nurture debate by linking the findings of the Human Genome project to the development of the brain. Startling findings have recently revealed that the genome is much smaller than we once thought, containing no more than 30,000-40,000 genes. Since this discovery, scientists have struggled to ... Leer más

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  • The Neural Basis of Free Will

    Criterial Causation

    A neuroscientific perspective on the mind–body problem that focuses on how the brain actually accomplishes mental causation.The issues of mental causation, consciousness, and free will have vexed philosophers since Plato. In this book, Peter Tse examines these unresolved issues from a neuroscientific perspective. In contrast with philosophers who use logic rather than data to argue whether mental ... Leer más

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  • Micro-, Meso- and Macro-Connectomics of the Brain

    Series series Research and Perspectives in Neurosciences
    This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map ... Leer más

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  • Algorithms in Computational Molecular Biology

    Techniques, Approaches and Applications

    de Yi Pan ...
    Series Libro 21 - Wiley Series in Bioinformatics
    This book represents the most comprehensive and up-to-date collection of information on the topic of computational molecular biology. Bringing the most recent research into the forefront of discussion, Algorithms in Computational Molecular Biology studies the most important and useful algorithms currently being used in the field, and provides related problems. It also succeeds where other titles ... Leer más

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  • The Phylogenetic Handbook

    A Practical Approach to Phylogenetic Analysis and Hypothesis Testing

    The Phylogenetic Handbook is a broad, hands on guide to theory and practice of nucleotide and protein phylogenetic analysis. This second edition includes six new chapters, covering topics such as Bayesian inference, tree topology testing and the impact of recombination on phylogenies, as well as a detailed section on molecular adaptation. The book has a stronger focus on hypothesis testing than ... Leer más

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  • Probabilistic Methods for Bioinformatics

    with an Introduction to Bayesian Networks

    The Bayesian network is one of the most important architectures for representing and reasoning with multivariate probability distributions. When used in conjunction with specialized informatics, possibilities of real-world applications are achieved. Probabilistic Methods for BioInformatics explains the application of probability and statistics, in particular Bayesian networks, to genetics. This ... Leer más

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  • Molecular Evolution

    A Statistical Approach

    de Ziheng Yang ...
    Studies of evolution at the molecular level have experienced phenomenal growth in the last few decades, due to rapid accumulation of genetic sequence data, improved computer hardware and software, and the development of sophisticated analytical methods. The flood of genomic data has generated an acute need for powerful statistical methods and efficient computational algorithms to enable their ... Leer más

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  • Bayesian Evolutionary Analysis with BEAST

    What are the models used in phylogenetic analysis and what exactly is involved in Bayesian evolutionary analysis using Markov chain Monte Carlo (MCMC) methods? How can you choose and apply these models, which parameterisations and priors make sense, and how can you diagnose Bayesian MCMC when things go wrong? These are just a few of the questions answered in this comprehensive overview of Bayesian ... Leer más

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  • Statistical Analysis of Microbiome Data with R

    Series series Mathematics and Statistics (R0)
    This unique book addresses the statistical modelling and analysis of microbiome data using cutting-edge R software. It includes real-world data from the authors’ research and from the public domain, and discusses the implementation of R for data analysis step by step. The data and R computer programs are publicly available, allowing readers to replicate the model development and data analysis ... Leer más

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