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  • Uncultivated Microorganisms

    Edición de Slava S. Epstein ...
    Series series Biomedical and Life Sciences (R0)
    In 1898, an Austrian microbiologist Heinrich Winterberg made a curious observation: the number of microbial cells in his samples did not match the number of colonies formed on nutrient media (Winterberg 1898). About a decade later, J. Amann qu- tified this mismatch, which turned out to be surprisingly large, with non-growing cells outnumbering the cultivable ones almost 150 times (Amann 1911). ... Leer más

    $215.09 USD

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  • Metabolic Engineering

    Principles and Methodologies

    Metabolic engineering is a new field with applications in the production of chemicals, fuels, materials, pharmaceuticals, and medicine at the genetic level. The field's novelty is in the synthesis of molecular biology techniques and the tools of mathematical analysis, which allow rational selection of targets for genetic modification through measurements and control of metabolic fluxes. The ... Leer más

    $188.99 USD

  • Iron Uptake in Bacteria with Emphasis on E. coli and Pseudomonas

    Series series Chemistry and Material Science (R0)
    Iron is essential for the growth of most bacteria because it serves as a cofactor for vital enzymes and for the components of the electron transport chain. Moreover, Iron plays an important role in bacterial pathogenicity; in fact, the iron transport systems in bacteria works as target for designing novel antibiotics. Because iron is not soluble under aerobic conditions, bacteria have had to find ... Leer más

    $49.49 USD

  • Biology of C Reactive Protein in Health and Disease

    Series series Biomedical and Life Sciences (R0)
    This book offers a comprehensive study of C-reactive protein (CRP) belonging to the pentraxin family, including a brief history of CRP, its structure, synthesis and evolution. Focusing on the emerging role of CRP and its clinical application in the field of disease biology, it details the pathophysiological role of CRP in a host of diseases such as cardiovascular disease, diabetes, cancers, ... Leer más

    $89.09 USD

  • Reprogramming Microbial Metabolic Pathways

    Edición de Xiaoyuan Wang, Peter Quinn, Jian Chen ...
    Series series Biomedical and Life Sciences (R0)
    Metabolic engineering has been developed over the past 20 years to become an important tool for the rational engineering of industrial microorganisms. This book has a particular interest in the methods and applications of metabolic engineering to improve the production and yield of a variety of different metabolites. The overall goal is to achieve a better understanding of the metabolism in ... Leer más

    $143.09 USD

  • A Systems Biology Approach to Study Metabolic Syndrome

    Series series Biomedical and Life Sciences (R0)
    The aim of this book is to provide the target audience, specifically students of Medicine, Biology, Systems Biology and Bioinformatics, as well as experienced researchers in research fields relevant to metabolic syndrome (MetS) with an overview of the challenges and opportunities in systems biology and how it can be used to tackle MetS. In particular, the aims are: (1) to provide an introduction ... Leer más

    $143.09 USD

  • Molecular mechanisms and physiology of disease

    Implications for Epigenetics and Health

    Series series Biomedical and Life Sciences (R0)
    In a simplified form, epigenetics refers to heritable changes in phenotype that are not due to changes in the underlying DNA sequence. In this book, epigenetic mechanisms of regulation and dysregulation in health and disease are explored in great depth. Detailed chapters on epigenetic processes including DNA methylation and chromatin post-translational modifications including potential ... Leer más

    $188.09 USD

  • Of Fish, Fly, Worm, and Man

    Lessons from Developmental Biology for Human Gene Function and Disease

    Series series Medicine (R0)
    The first complete genome sequence of a multicellular organism, Caenorhabditis elegans, has been determined recently. Several more will follow soon, among them the genome sequences of Drosophila melanogaster and the human. With these achievements, the stage is set for the next phase of "large-scale" biology, the study of the function of genes and the interactions between their protein products. ... Leer más

    $49.49 USD

  • Phosphoinositide 3-kinase in Health and Disease

    Volume 1

    Series series Biomedical and Life Sciences (R0)
    From humble beginnings over 25 years ago as a lipid kinase activity associated with certain oncoproteins, PI3K (phosphoinositide 3-kinase) has been catapulted to the forefront of drug development in cancer, immunity and thrombosis, with the first clinical trials of PI3K pathway inhibitors now in progress. Here we give a brief overview of some key discoveries in the PI3K area and their impact, and ... Leer más

    $188.09 USD

  • Microbial Biochemistry

    de G.N. Cohen ...
    Series series Biomedical and Life Sciences (R0)
    Microbial physiology, biochemistry, and genetics allowed the formulation of concepts that turned out to be important in the study of higher organisms. In the first section, the principles of bacterial growth are given, as well as the description of the different layers that enclose the bacterial cytoplasm, and their role in obtaining nutrients from the outside media through different permeability ... Leer más

    $206.99 USD

  • Inorganic Polyphosphates in Eukaryotic Cells

    Series series Biomedical and Life Sciences (R0)
    The book elucidates the role of inorganic polyphosphates in eukaryotic cells, from fungi and protozoa to human being. To date, there is plenty of evidence that these anionic biopolymers occurring in the cells of all living organisms, from bacteria to humans, perform numerous regulatory functions. The book describes the evolution of PolyPs, their role in lower eukaryotes and their involvement in ... Leer más

    $143.09 USD

  • The Minimal Cell

    The Biophysics of Cell Compartment and the Origin of Cell Functionality

    Edición de Pier Luigi Luisi, Pasquale Stano ...
    Series series Biomedical and Life Sciences (R0)
    In the last ten years there has been a considerable increase of interest on the notion of the minimal cell. With this term we usually mean a cell-like structure containing the minimal and sufficient number of components to be defined as alive, or at least capable of displaying some of the fundamental functions of a living cell. In fact, when we look at extant living cells we realize that thousands ... Leer más

    $143.09 USD