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1 - 12 de 12 resultados para “shuyen ho”
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  • Design and Analysis of Subgroups with Biopharmaceutical Applications

    Edición de Naitee Ting, Joseph C. Cappelleri, Shuyen Ho, (Din) Ding-Geng Chen ...
    Series series Mathematics and Statistics (R0)
    This book provides an overview of the theories and applications on subgroups in the biopharmaceutical industry. Drawing from a range of expert perspectives in academia and industry, this collection offers an overarching dialogue about recent advances in biopharmaceutical applications, novel statistical and methodological developments, and potential future directions.The volume covers topics in ... Leer más

    $80.99 USD

  • Phase II Clinical Development of New Drugs

    de Ding-Geng Chen, Joseph C. Cappelleri, Naitee Ting, Shuyen Ho ...
    Series series Mathematics and Statistics (R0)
    This book focuses on how to appropriately plan and develop a Phase II program, and how to design Phase II clinical trials and analyze their data. It provides a comprehensive overview of the entire drug development process and highlights key questions that need to be addressed for the successful execution of Phase II, so as to increase its success in Phase III and for drug approval. Lastly it warns ... Leer más

    $107.09 USD

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  • Decision Making in a World of Comparative Effectiveness Research

    A Practical Guide

    Edición de Howard G. Birnbaum, Paul E. Greenberg ...
    Series series Medicine (R0)
    In the past decade there has been a worldwide evolution in evidence-based medicine that focuses on real-world Comparative Effectiveness Research (CER) to compare the effects of one medical treatment versus another in real world settings. While most of this burgeoning literature has focused on research findings, data and methods, Howard Birnbaum and Paul Greenberg (both of Analysis Group) have ... Leer más

    $89.09 USD

  • Biosimulation in Biomedical Research, Health Care and Drug Development

    Edición de Erik Mosekilde, Olga Sosnovtseva, Amin Rostami-Hodjegan ...
    Series series Biomedical and Life Sciences (R0)
    Biosimulation is an approach to biomedical research and the treatment of patients in which computer modeling goes hand in hand with experimental and clinical work. Constructed models are used to interpret experimental results and to accumulate information from experiment to experiment.This book explains the concepts used in the modeling of biological phenomena and goes on to present a series of ... Leer más

    $143.99 USD

  • Quantitative Decisions in Drug Development

    de Christy Chuang-Stein, Simon Kirby ...
    Series series Mathematics and Statistics (R0)
    This book offers a high-level treatise of evidence-based decisions in drug development. Because of the inseparable relationship between designs and decisions, a good portion of this book is devoted to the design of clinical trials. The book begins with an overview of product development and regulatory approval pathways. It then discusses how to incorporate prior knowledge into study design and ... Leer más

    $62.99 USD

  • Statistical Applications for Chemistry, Manufacturing and Controls (CMC) in the Pharmaceutical Industry

    de Richard K. Burdick, Jorge Quiroz, Lori B. Pfahler, Lanju Zhang, Leslie Sidor, Kimberly Vukovinsky, David J. LeBlond ...
    Series series Mathematics and Statistics (R0)
    This book examines statistical techniques that are critically important to Chemistry, Manufacturing, and Control (CMC) activities. Statistical methods are presented with a focus on applications unique to the CMC in the pharmaceutical industry.The target audience consists of statisticians and other scientists who are responsible for performing statistical analyses within a CMC environment. Basic ... Leer más

    $80.99 USD

  • Group Sequential and Confirmatory Adaptive Designs in Clinical Trials

    de Gernot Wassmer, Werner Brannath ...
    Series series Mathematics and Statistics (R0)
    This book provides an up-to-date review of the general principles of and techniques for confirmatory adaptive designs. Confirmatory adaptive designs are a generalization of group sequential designs. With these designs, interim analyses are performed in order to stop the trial prematurely under control of the Type I error rate. In adaptive designs, it is also permissible to perform a data-driven ... Leer más

    $134.99 USD

  • Nonclinical Statistics for Pharmaceutical and Biotechnology Industries

    de Max Kuhn, Ian Peers, Stan Altan ...
    Series series Mathematics and Statistics (R0)
    This book serves as a reference text for regulatory, industry and academic statisticians and also a handy manual for entry level Statisticians. Additionally it aims to stimulate academic interest in the field of Nonclinical Statistics and promote this as an important discipline in its own right. This text brings together for the first time in a single volume a comprehensive survey of methods ... Leer más

    $170.99 USD

  • Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

    Order-Restricted Analysis of Microarray Data

    Edición de Dan Lin, Ziv Shkedy, Daniel Yekutieli, Dhammika Amaratunga, Luc Bijnens ...
    Series series Mathematics and Statistics (R0)
    This book focuses on the analysis of dose-response microarray data in pharmaceutical settings, the goal being to cover this important topic for early drug development experiments and to provide user-friendly R packages that can be used to analyze this data. It is intended for biostatisticians and bioinformaticians in the pharmaceutical industry, biologists, and biostatistics/bioinformatics ... Leer más

    $49.49 USD

  • Clinical Data Analysis on a Pocket Calculator

    Understanding the Scientific Methods of Statistical Reasoning and Hypothesis Testing

    de Ton J. Cleophas, Aeilko H. Zwinderman ...
    Series series Biomedical and Life Sciences (R0)
    In medical and health care the scientific method is little used, and statistical software programs are experienced as black box programs producing lots of p-values, but little answers to scientific questions. The pocket calculator analyses appears to be, particularly, appreciated, because they enable medical and health professionals and students for the first time to understand the scientific ... Leer más

    $80.99 USD

  • The Essential Guide to N-of-1 Trials in Health

    Edición de Jane Nikles, Geoffrey Mitchell ...
    Series series Biomedical and Life Sciences (R0)
    N-of-1 trials, a type of individualized randomized controlled trial, are relevant to almost every discipline in medicine and psychology. They can tell the clinician with precision whether a treatment works in that individual, which distinguishes from the information available from most other trial designs. They have the potential to revolutionize the way clinical medicine is practiced.Whether you ... Leer más

    $152.99 USD

  • Permutation Testing for Isotonic Inference on Association Studies in Genetics

    de Luigi Salmaso, Rosa Arboretti, Livio Corain, Dario Mazzaro ...
    Series series Mathematics and Statistics (R0)
    The purpose of this book is to illustrate a new statistical approach to test allelic association and genotype-specific effects in the genetic study of diseases. There are some parametric and non-parametric methods available for this purpose. We deal with population-based association studies, but comparisons with other methods will also be drawn, analysing the advantages and disadvantages of each ... Leer más

    $40.99 USD