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  • BRAF Targets in Melanoma

    Biological Mechanisms, Resistance, and Drug Discovery

    Edición de Ryan J. Sullivan ...
    Series series Medicine (R0)
    This volume contains a collection of writings from the leaders in the fields of Molecular Biology and Melanoma Research which will begin to tell the ever-expanding story of the most recent findings, discoveries, and potential of BRAF-directed targets in melanoma. Recent research has shown that BRAF inhibitors are effective for a short period of time, but there is little hope that this drugs as ... Leer más

    $89.99 USD

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  • Principles and Practice of Clinical Research

    The third edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory ... Leer más

    $112.49 USD

  • Platelets in Thrombotic and Non-Thrombotic Disorders

    Pathophysiology, Pharmacology and Therapeutics: an Update

    Series series Biomedical and Life Sciences (R0)
    This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is ... Leer más

    $332.09 USD

  • Anticancer Genes

    Edición de Stefan Grimm ...
    Series series Biomedical and Life Sciences (R0)
    This book discusses the emergence of a new class of genes with a specific anticancer activity. These genes, recently defined as “Anticancer Genes”, are reviewed in individual chapters on their mode of action, the specific cell death signals they induce, and the status of attempts to translate them into clinical application.Anticancer Genes provides an overview of this nascent field, its genesis, ... Leer más

    $89.99 USD

  • Pathogenesis of Mycobacterium tuberculosis and its Interaction with the Host Organism

    Edición de John D. McKinney, Jean Pieters ...
    Series series Biomedical and Life Sciences (R0)
    Mycobacterium tuberculosis is one of the most notorious pathogens on earth, causing the death of approximately 1.5 million people annually. A major problem in the fight against tuberculosis is the emergence of strains that have acquired resistance to all available antibiotics. One key to the success of M. tuberculosis as a pathogen is its ability to circumvent host immune responses at different ... Leer más

    $143.09 USD

  • Antibiotic Discovery and Development

    Series series Biomedical and Life Sciences (R0)
    This volume covers all aspects of the antibiotic discovery and development process through Phase II/III. The contributors, a group of highly experienced individuals in both academics and industry, include chapters on the need for new antibiotic compounds, strategies for screening for new antibiotics, sources of novel synthetic and natural antibiotics, discovery phases of lead development and ... Leer más

    $215.99 USD

  • Blue Biotechnology

    From Gene to Bioactive Product

    Series series Biomedical and Life Sciences (R0)
    This book describes the discovery of molecules from unexploited extreme marine environments, and presents new approaches in marine genomics. It combines the current state of knowledge in marine genomics and advanced natural products’ chemistry to pursue the sustainable production of novel secondary metabolites (lead compounds), as well as pharmacologically active peptides/proteins, with ... Leer más

    $170.99 USD

  • Arterial Chemoreceptors in Physiology and Pathophysiology

    Series series Biomedical and Life Sciences (R0)
    Every three years, the International Society for Arterial Chemoreception (ISAC) arranges a Meeting to bring together all of the major International research groups investigating the general topic of oxygen sensing in health and disease, with a prime focus upon systemic level hypoxia and carotid body function. This volume summarises the proceedings of the XIXth meeting of the Society, held in Leeds ... Leer más

    $89.99 USD

  • Therapeutic Vaccination Strategies

    Edición de P. Walden, W. Sterry, H. Hennekes ...
    Series series Medicine (R0)
    The induction of immune responses against tumor cells by vaccination is rapidly evolving as a therapeutic modality with new potentials for the treatment of cancer. It is based on the fact that our immune system can identify tumor cells and, once activated, is capable of developing specific immunity against the neoplastic cells. Numerous observations and intense research clearly document the major ... Leer más

    $49.99 USD

  • New Strategies in Stroke Intervention

    Ionic Transporters, Pumps, and New Channels

    Edición de Lucio Annunziato ...
    Series series Biomedical and Life Sciences (R0)
    Ischemic brain damage represents a major source of morbidity and mortality in westernized society and poses a significant financial burden on the health care system. To date, few effective therapies have been realized. Recent evidence, however, suggests that channels, pumps, and ionic exchangers are involved in CNS ischemia and ischemic stroke, but the potential contribution of these channels for ... Leer más

    $98.09 USD

  • Safety and Efficacy of Gene-Based Therapeutics for Inherited Disorders

    Edición de Nicola Brunetti-Pierri ...
    Series series Biomedical and Life Sciences (R0)
    In this book, leading international experts analyze state-of-the-art advances in gene transfer vectors for applications in inherited disorders and also examine the toxicity profiles of these methods. The authors discuss the strengths and weaknesses of available vectors in the clinical setting, and specifically focus on the challenges and possible solutions that researchers are testing in order to ... Leer más

    $143.09 USD