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  • PI3K-mTOR in Cancer and Cancer Therapy

    Series series Medicine (R0)
    In the post human-genome project era, cancer specific genomic maps are redesigning tumor taxonomy by evolving from histopathology to molecular pathology. The success of a cancer drug today is fundamentally based on the success in identifying target genes that control beneficial pathways. The overwhelming power of genomics and proteomics has enlightened researchers about the fact that the PI3K-mTOR ... Leer más

    $143.99 USD

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  • Anticancer Genes

    Edición de Stefan Grimm ...
    Series series Biomedical and Life Sciences (R0)
    This book discusses the emergence of a new class of genes with a specific anticancer activity. These genes, recently defined as “Anticancer Genes”, are reviewed in individual chapters on their mode of action, the specific cell death signals they induce, and the status of attempts to translate them into clinical application.Anticancer Genes provides an overview of this nascent field, its genesis, ... Leer más

    $89.99 USD

  • Platelets in Thrombotic and Non-Thrombotic Disorders

    Pathophysiology, Pharmacology and Therapeutics: an Update

    Series series Biomedical and Life Sciences (R0)
    This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is ... Leer más

    $332.09 USD

  • Resistance of Cancer Cells to CTL-Mediated Immunotherapy

    Edición de Benjamin Bonavida, Salem Chouaib ...
    Series series Biomedical and Life Sciences (R0)
    This comprehensive volume explores the latest research on the mechanisms of resistance in cancer cells to CTL-mediated immunotherapy. Chapter topics discuss cell-mediated immunity as the result of cytotoxic T-lymphocytes (CTL) directed specifically against cancer cells. In addition, the volume reviews how CTL mediate the cytotoxic activity, in large part, by the indication of apoptosis; hence, ... Leer más

    $89.09 USD

  • Arterial Chemoreceptors in Physiology and Pathophysiology

    Series series Biomedical and Life Sciences (R0)
    Every three years, the International Society for Arterial Chemoreception (ISAC) arranges a Meeting to bring together all of the major International research groups investigating the general topic of oxygen sensing in health and disease, with a prime focus upon systemic level hypoxia and carotid body function. This volume summarises the proceedings of the XIXth meeting of the Society, held in Leeds ... Leer más

    $89.99 USD

  • Rabies in Man and Animals

    Rabies is the deadliest zoonotic disease that threatens humans and animals on all continents except Antarctica. Asia and Africa are worst affected as more than 95 per cent of rabies associated human deaths occur in these regions. India alone bears about 36 per cent of the global human rabies burden. Dogs are the main transmitters of rabies that potentially threaten over 3 billion people in Asia ... Leer más

    $143.99 USD

  • Antitumor Potential and other Emerging Medicinal Properties of Natural Compounds

    Edición de Evandro Fei Fang, Tzi Bun Ng ...
    Series series Biomedical and Life Sciences (R0)
    The modern unhealthy diet and lifestyle in conjunction with pathogens, environmental carcinogens and multiple other risk factors increase humans’ susceptibility to different diseases exemplified by elevated levels of cancers, cardiovascular and communicable diseases. Screening of potential drugs from medicinal plants and animals provides a promising strategy for the alleviation of the impact of ... Leer más

    $143.99 USD

  • Metabolic Control

    Edición de Stephan Herzig ...
    Series series Biomedical and Life Sciences (R0)
    The HEP issue on Metabolic Control provides a state-of the art overview over both classical concepts and emerging areas in metabolism and associated disorders. In this context, metabolic control is highlighted at various levels of complexity ranging from transcriptional mechanisms in metabolic pathway control over metabolic communication routes in physiology and pathophysiology to current ... Leer más

    $188.09 USD

  • Resistance to Proteasome Inhibitors in Cancer

    Molecular Mechanisms and Strategies to Overcome Resistance

    Edición de Q. Ping Dou ...
    Series series Biomedical and Life Sciences (R0)
    The book explores cutting-edge strategies to overcome proteasome inhibitor resistance, including the second generation 20S proteasome inhibitors, novel combinational therapies, and new targets in the ubiquitin-proteasome pathway (e.g., ubiquitin E3 ligases, deubiquitinases, 19S proteasomal ATPases, histone deacetylases, oxidative stress and proteotoxic stress pathways and pharmacogenomic signature ... Leer más

    $143.99 USD

  • High Throughput Screening for Novel Anti-Inflammatories

    Edición de Michael Kahn ...
    Series series Progress in Inflammation Research
    Combinatorial chemistry in conjunction with High Throughput Screening (HTS) is revolutionizing the drug discovery process. Yet, we have much to learn about the integration of these powerful techniques with information from genomics, proteomics, computation and pharmacokinetics before dramatic increases in the drug discovery/development processes can be achieved. The chapters in this book represent ... Leer más

    $143.99 USD

  • Textbook of Cell Signalling in Cancer

    An Educational Approach

    Series series Biomedical and Life Sciences (R0)
    This book provides a simplified, yet comprehensive, overview of the signalling pathways operating between and inside cells, which will help younger oncologists find their way in the labyrinth of signalling pathways and in the multitude of signals and signal receptors, transducers and effectors that contribute to oncogenesis.This comprehensive reference text is based on the master’s courses ... Leer más

    $49.49 USD

  • PARP Inhibitors for Cancer Therapy

    Series series Medicine (R0)
    PARP Inhibitors for Cancer Therapy provides a comprehensive overview of the role of PARP in cancer therapy. The volume covers the history of the discovery of PARP (poly ADP ribose polymerase) and its role in DNA repair. In addition, a description of discovery of the PARP family, and other DNA maintenance-associated PARPs will also be discussed. The volume also features a section on accessible ... Leer más

    $143.09 USD