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  • Genetic Polymorphisms and Susceptibility to Disease

    Genetic Polymorphisms and Susceptibity to Disease provides a reference for established researchers in genetic research. The book provides a broad but thorough overview of how allelic gene differences influence disease susceptibility in the human population, and will be a useful reference to researchers across a range of disciplines, for example, on ... Leer más

    $325.00 USD

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  • The Molecular Basis of Cancer E-Book

    The Molecular Basis of Cancer E-Book

    2015 BMA Medical Book Awards Highly Commended in Oncology Category!The Molecular Basis of Cancer arms you with the latest knowledge and cutting-edge advances in the battle against cancer. This thoroughly revised, comprehensive oncology reference explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of this disease. A team of ... Leer más

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  • DNA Repair in Cancer Therapy

    Molecular Targets and Clinical Applications

    Edición de Mark R. Kelley ...
    Cancer therapeutics include an ever-increasing array of tools at the disposal of clinicians in their treatment of this disease. However, cancer is a tough opponent in this battle, and current treatments, which typically include radiotherapy, chemotherapy and surgery, are not often enough to rid the patient of his or her cancer. Cancer cells can become resistant to the treatments directed at them, ... Leer más

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  • DNA Repair in Cancer Therapy

    Molecular Targets and Clinical Applications

    DNA Repair and Cancer Therapy: Molecular Targets and Clinical Applications, Second Edition provides a comprehensive and timely reference that focuses on the translational and clinical use of DNA repair as a target area for the development of diagnostic biomarkers and the enhancement of cancer treatment. Experts on DNA repair proteins from all areas of cancer biology research take readers from ... Leer más

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  • RNA Interference

    Application to Drug Discovery and Challenges to Pharmaceutical Development

    Edición de Paul H. Johnson ...
    RNA Interference: Application to Drug Discovery and Challenges to Pharmaceutical Development provides a general overview of this rapidly emerging field, with a strong emphasis on issues and aspects that are important to a drug development team. The first part covers more general background of RNA interference and its application in drug discovery. In the second part, the book addresses siRNA ... Leer más

    $129.00 USD

  • Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants

    Edición de Yvonne Will, James A. Dykens ...
    Developed as a one-stop reference source for drug safety and toxicology professionals, this book explains why mitochondrial failure is a crucial step in drug toxicity and how it can be avoided.• Covers both basic science and applied technology / methods• Allows readers to understand the basis of mitochondrial function, the preclinical assessments used, and what they reveal about drug effects• ... Leer más

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  • Therapeutic Monoclonal Antibodies

    From Bench to Clinic

    Edición de Zhiqiang An ...
    70-chapter authoritative reference that covers therapeutic monoclonal antibody discovery, development, and clinical applications while incorporating principles, experimental data, and methodologies.First book to address the discovery and development of antibody therapeutics in their entirety.Most chapters contain experimental data to illustrate the principles described in them.Authors provide ... Leer más

    $198.00 USD

  • Progress in Genomic Medicine

    From Research to Clinical Application

    de Moyra Smith ...
    Progress in Genomic Medicine: From Research to Clinical Application provides a careful synthesis of the foundations, current trends and translational challenges in genomic medicine, clarifying pathways forward and enabling genomic medicine research and implementation across clinical settings and treatment development. Sections address the history and growth of genetic medicine, with a discussion ... Leer más

    $134.99 USD

  • Mitochondrial DNA, Mitochondria, Disease and Stem Cells

    Edición de Justin C. St. John ...
    Series series Biomedical and Life Sciences (R0)
    This volume investigates how the mitochondrial genome is transmitted, segregated, and inherited. It starts by describing mtDNA mutations and deletions and how these impact on the offspring’s well-being. It progresses to discuss how mutations to the mtDNA-nuclear-encoded transcription, replication and translational factors lead to mtDNA-depletion syndromes and how these affect cellular function and ... Leer más

    $98.99 USD

  • Mitochondrial Diseases

    de Wiley ...
    Series series Life Science Research Fundamentals
    This collection of reviews and protocols provides the reader with an introduction to the current state of knowledge on how various diseases are related to mitochondrial dysfunction. Mitochondria contain their own genome, a small, circular double-stranded DNA (mtDNA), and alterations in mtDNA may play an important role in the multistep carcinogenesis of at least some types of human cancer. In ... Leer más

    $32.00 USD

  • Molecular Biology of Cancer

    Series series Advanced Texts
    Molecular Biology of Cancer has been extensively revised and covers heredity cancer, microarray technology and increased study of childhood cancers. It continues to provide a detailed overview of the process which lead to the development and proliferation of cancer cells, including the techniques available for their study. It also describes the means by which tumor suppressor genes and oncogenes ... Leer más

    $140.99 USD

  • Systems Biology of Cancer

    Edición de Sam Thiagalingam ...
    With over two hundred types of cancer diagnosed to date, researchers the world over have been forced to rapidly update their understanding of the biology of cancer. In fact, only the study of the basic cellular processes, and how these are altered in cancer cells, can ultimately provide a background for rational therapies. Bringing together the state-of-the-art contributions of international ... Leer más

    $92.99 USD