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  • DNA Helicases and DNA Motor Proteins

    Edición de Maria Spies ...
    Series series Biomedical and Life Sciences (R0)
    In recent years, a number of groundbreaking structural and mechanistic studies deepened our understanding of helicase mechanisms and established new approaches for their analyses. Many fundamental mechanistic questions ranging from the mechanism of force generation, mechanochemical coupling to distinct mechanisms by which the same enzyme translocates on DNA removing obstacles, unwinds DNA and/or ... Leer más

    $143.09 USD

  • Single-Molecule Enzymology: Nanomechanical Manipulation and Hybrid Methods

    Series Libro 582 - Methods in Enzymology
    Single-Molecule Enzymology, Part B, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in single-molecule enzymology, and includes sections on such topics as force-based and hybrid approaches, fluorescence, high-throughput sm enzymology, and nanopore and ... Leer más

    $179.09 USD

  • Single-Molecule Enzymology: Fluorescence-Based and High-Throughput Methods

    Series Libro 581 - Methods in Enzymology
    Single-Molecule Enzymology, Part A, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in single-molecule enzymology, and includes sections on such topics as force-based and hybrid approaches, fluorescence, high-throughput sm enzymology, nanopores, and ... Leer más

    $179.09 USD

  • Mechanisms of DNA Recombination and Genome Rearrangements: Methods to Study Homologous Recombination

    Series Libro 600 - Methods in Enzymology
    Mechanisms of DNA Recombination and Genome Rearrangements: Methods to Study Homologous Recombination, Volume 600, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Homologous genetic recombination remains the most enigmatic process in DNA metabolism. The molecular machines of recombination ... Leer más

    $179.09 USD

  • Mechanisms of DNA Recombination and Genome Rearrangements: Intersection Between Homologous Recombination, DNA Replication and DNA Repair

    Series Libro 601 - Methods in Enzymology
    Mechanisms of DNA Recombination and Genome Rearrangements: Intersection between Homologous Recombination, DNA Replication and DNA Repair, Volume 601, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Homologous genetic recombination remains the most enigmatic process in DNA metabolism. The ... Leer más

    $179.09 USD

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  • Introduction to Molecular Medicine

    Series series Medicine (R0)
    How will increased understanding of the human genome affect our ability to diagnose and treat disease? The subject of recombinant DNA technology is no longer limited to the research laboratory; it is being discussed in ever-widening medical circles. Introduction to Molecular Medicine is especially written for the physician who is not a genetics expert but wishes to understand this new science and ... Leer más

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  • Non Coding RNAs in Plants

    Series series Biomedical and Life Sciences (R0)
    In the most recent years, each of the RNA silencing pathways of plants have appeared to generate ncRNAs with dedicated functions, specialized biological activities and specific functional scopes. RNA silencing plays a crucial role in coordinating the expression, stability, protection and inheritance of eukaryotic genomes. It compromises several mechanisms, that invariably depend on core small non ... Leer más

    $188.99 USD

  • Cystogenesis

    Edición de Jong Hoon Park, Curie Ahn ...
    Series series Biomedical and Life Sciences (R0)
    Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating ... Leer más

    $89.09 USD

  • Trinucleotide Diseases and Instability

    Edición de Ben A. Oostra ...
    Series series Biomedical and Life Sciences (R0)
    Till recently, mutations in genes were described in textbooks as deletions or point mutations. These mutations can be inherited from a parent or they are de novo alterations. The discovery in 1991 that human disease can be caused by large-scale ex pansion of highly unstable trinucleotide repeats has elucidated a new mutation mechanism, heritable unstable DNA. In the subsequent years more then 10 ... Leer más

    $49.49 USD

  • Molecular Genetic Epidemiology

    A Laboratory Perspective

    Edición de Ian N.M. Day ...
    Series series Biomedical and Life Sciences (R0)
    This volume describes high-throughput approaches to a series of robust, established methodologies in molecular genetic studies of population samples. Such developments have been essential not only to linkage and association studies of single-gene and complex traits in humans, animals and plants, but also to the characterisation of clone banks, for example in mapping of genomes. Chapters have been ... Leer más

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  • Long Non-Coding RNAs

    Edición de Durdica Ugarkovic ...
    Series series Biomedical and Life Sciences (R0)
    Long non-coding RNAs (lncRNAs), tentatively defined as ncRNAs of more than two hundred nucleotides in length, are characterized by the complexity and diversity of their sequences and mechanisms of action. Based on genome-wide studies, more than 3,300 of them exist, but to date only the limited number of functional lncRNAs have been identified and characterized. Nonetheless, lncRNAs have emerged as ... Leer más

    $143.09 USD