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  • The Science of Stem Cells

    Introduces all of the essential cell biology and developmental biology background for the study of stem cellsThis book gives you all the important information you need to become a stem cell scientist. It covers the characterization of cells, genetic techniques for modifying cells and organisms, tissue culture technology, transplantation immunology, properties of pluripotent and tissue specific ... Leer más

    $93.00 USD

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  • Trends in Stem Cell Proliferation and Cancer Research

    Series series Biomedical and Life Sciences (R0)
    The book will discuss the molecular mechanisms of cancer diseases, stem cell proliferation and transformation into cancer cells beyond the physiological processes that occur in normal stem cell biology. Some of the key oncogenic events in cancer and their signaling pathways that regulate cell division cycle progression will be described considering prospects for using such knowledge in advanced ... Leer más

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  • New Approaches to Drug Discovery

    Series Libro 232 - Handbook of Experimental Pharmacology
    This volume gives an overview of state of the art technologies and future developments in the field of preclinical pharmaceutical research. A balanced mix of experts from academia and industry give insight in selected new developments in the drug discovery pathway. The topics cover the different parts of the drug discovery process, starting with new developments in the target identification and ... Leer más

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  • Jak-Stat Signaling : From Basics to Disease

    Edición de Thomas Decker, Mathias Müller ...
    Series series Biomedical and Life Sciences (R0)
    JAK tyrosine kinases and STAT transcription factors constitute a signaling pathway, which is activated by cytokines. By activating gene transcription it regulates essential biological responses to environmental cues. The Jak-Stat pathway is involved in the regulation of cell development, differentiation, proliferation and apoptosis. Improper function may contribute to hematopoietic malignancies ... Leer más

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  • Chromatin

    Structure & Function

    The Third Edition of Chromatin: Structure and Function brings the reader up-to-date with the remarkable progress in chromatin research over the past three years. It has been extensively rewritten to cover new material on chromatin remodeling, histone modification, nuclear compartmentalization, DNA methylation, and transcriptional co-activators and co-repressors. The book is written in a clear and ... Leer más

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  • Human Amniotic Membrane: Basic Science And Clinical Application

    This book is a comprehensive guide for all tissue bank operators to screen, procure and process amniotic membrane for clinical application.The amnion comes close to being the ideal biological membrane or dressing — readily available, inexpensive to procure and process. Its basic science is discussed in detail — anatomy, biological and biomechanical properties.It can be procured from the placenta ... Leer más

    $106.99 USD

  • Bioprobes

    Biochemical Tools for Investigating Cell Function

    Edición de H. Osada ...
    Series series Biomedical and Life Sciences (R0)
    Rapid advances in the study of the molecular basis of mammalian cell proliferation, differentiation, and apoptosis have made it possible to develop new screening systems for isolating from microbial metabolites specific inhibitors of mammalian cell functions. "Bioprobes" is the term used to describe these inhibitors, which are extremely useful agents in investigating the molecular and chemical ... Leer más

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  • Circadian Rhythms and Their Impact on Aging

    Series series Biomedical and Life Sciences (R0)
    Biological rhythms time the ebb and flow of virtually every physiological process, and their mutual coordination guarantees the integrity of the organism over space and time. Aging leads to the disintegration of this coordination, as well as to changes in the amplitude and/or frequency of the underlying rhythms. The results of this are accelerated loss of health during aging, and in experimental ... Leer más

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  • Hypoxia and Cancer

    Biological Implications and Therapeutic Opportunities

    Edición de Giovanni Melillo ...
    Series series Biomedical and Life Sciences (R0)
    The imbalance between rapidly proliferating tumor cells and inadequate and inefficient tumor vasculature leads to a decrease in oxygen levels (hypoxia and/or anoxia) in tumor tissues. Intra-tumor hypoxia profoundly affects the biological behavior of cancer cells, which become resistant to conventional therapies and acquire a more invasive and metastatic phenotype. Hypoxia is a hallmark of the ... Leer más

    $143.99 USD

  • Pluripotency in Domestic Animal Cells

    Series series Biomedical and Life Sciences (R0)
    This addition to the Springer Brief in Stem Cells series focuses on aspects related to the specific mechanisms that ensure and control pluripotency and cell commitment in domestic animal species. This topic is generating rapidly-increasing interest due to the great potential for domestic animal species to be used as intermediate biomedical models, between the mouse and the human. The Brief ... Leer más

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  • Safety, Ethics and Regulations

    Edición de Phuc Van Pham, Achim Rosemann ...
    Series series Biomedical and Life Sciences (R0)
    This invaluable resource discusses the saftey, ethics, and regulations of developing stem cell clinical applications. Each chapter is contributed by a preeminent scientist in the field and covers such topics as clinical safety of stem cell gene therapy, the patentability of hESC technologies, international guidelines, challenges to international stem cell clinical trials, worldwide regulations ... Leer más

    $143.99 USD