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“j eric mcduffie”

1 - 12 de 12 resultados para “j eric mcduffie”
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  • Drug Discovery Toxicology

    From Target Assessment to Translational Biomarkers

    Edición de J. Eric McDuffie, Andrew J. Olaharski, Brandon D. Jeffy, Yvonne Will ...
    As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process.• Guides researchers as to what drug safety experiments are both practical and useful• Covers a variety of key topics – safety lead optimization, in vitro-in vivo ... Leer más

    $181.00 USD

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  • The Future of Drug Discovery

    Who Decides Which Diseases to Treat?

    de Tamas Bartfai, Graham V. Lees ...
    The Future of Drug Discovery: Who decides which diseases to treat? provides a timely and detailed look at the efforts of the pharmaceutical industry and how they relate, or should relate, to societal needs. The authors posit that as a result of increasing risk aversion and accelerated savings in research and development, the industry is not developing drugs for increasingly prevalent diseases, ... Leer más

    $40.99 USD

  • Cardiovascular Diseases

    From Molecular Pharmacology to Evidence-Based Therapeutics

    de Y. Robert Li ...
    Written in an accessible style and consistent format, the book covers both the fundamentals and advances in the pharmacology of cardiovascular drugs, as well as their integrated applications in the management of individual cardiovascular diseases.• Integrates fundamentals and recent advances regarding cardiovascular drugs, blending basic and clinical sciences needed to effectively understand and ... Leer más

    $123.00 USD

  • ADME and Translational Pharmacokinetics / Pharmacodynamics of Therapeutic Proteins

    Applications in Drug Discovery and Development

    de Honghui Zhou, Frank-Peter Theil ...
    With an emphasis on the fundamental and practical aspects of ADME for therapeutic proteins, this book helps readers strategize, plan and implement translational research for biologic drugs.Details cutting-edge ADME (absorption, distribution, metabolism and excretion) and PKPD (pharmacokinetic / pharmacodynamics) modeling for biologic drugsCombines theoretical with practical aspects of ADME in ... Leer más

    $133.00 USD

  • Attrition in the Pharmaceutical Industry

    Reasons, Implications, and Pathways Forward

    de Alexander Alex, C. John Harris, Dennis A. Smith ...
    With a focus on case studies of R&D programs in a variety of disease areas, the book highlights fundamental productivity issues the pharmaceutical industry has been facing and explores potential ways of improving research effectiveness and efficiency.Takes a comprehensive and holistic approach to the problems and potential solutions to drug compound attritionTackles a problem that adds billions of ... Leer más

    $126.00 USD

  • High-Throughput Screening Methods in Toxicity Testing

    Edición de Pablo Steinberg ...
    Explores the benefits and limitations of the latest high-throughput screening methodsWith its expert coverage of high-throughput in vitro screening methods for toxicity testing, this book makes it possible for researchers to accelerate and streamline the evaluation and risk assessment of chemicals and drugs for toxicity. Moreover, it enables them to comply with the latest standards set forth by ... Leer más

    $152.00 USD

  • Predictive ADMET

    Integrated Approaches in Drug Discovery and Development

    de Jianling Wang, Laszlo Urban ...
    This book helps readers integrate in silico, in vitro, and in vivo ADMET (absorption, distribution, metabolism, elimination and toxicity) and PK (pharmacokinetics) data with routine testing applications so that pharmaceutical scientists can diagnose ADMET problems and present appropriate recommendations to move drug discovery programs forward.The book introduces the current clinical practice for ... Leer más

    $143.00 USD

  • Oral Formulation Roadmap from Early Drug Discovery to Development

    Edición de Elizabeth Kwong ...
    Detailing formulation approaches by stage of discovery to early development, this book gives a “playbook” of practical and efficient strategies to formulate drug candidates with the least chance of failing in clinical development.• Comes from contributing authors with experience developing formulations on the frontlines of the pharmaceutical industry• Focuses on pre (or non-) clinical and early ... Leer más

    $138.00 USD

  • Oral Bioavailability Assessment

    Basics and Strategies for Drug Discovery and Development

    de Ayman F. El-Kattan, Mike S. Lee ...
    Series series Wiley Series on Pharmaceutical Science and Biotechnology: Practices, Applications and Methods
    Specifically geared to personnel in the pharmaceutical and biotechnology industries, this book describes the basics and challenges of oral bioavailability – one of the most significant hurdles in drug discovery and development.• Describes approaches to assess pharmacokinetics and how drug efflux and uptake transporters impact oral bioavailability• Helps readers reduce the failure rate of drug ... Leer más

    $155.00 USD

  • Antibody-Drug Conjugates

    Fundamentals, Drug Development, and Clinical Outcomes to Target Cancer

    Edición de Kenneth J. Olivier Jr., Sara A. Hurvitz ...
    Providing practical and proven solutions for antibody-drug conjugate (ADC) drug discovery success in oncology, this book helps readers improve the drug safety and therapeutic efficacy of ADCs to kill targeted tumor cells.• Discusses the basics, drug delivery strategies, pharmacology and toxicology, and regulatory approval strategies• Covers the conduct and design of oncology clinical trials and ... Leer más

    $138.00 USD

  • From Artemisia annua L. to Artemisinins

    The Discovery and Development of Artemisinins and Antimalarial Agents

    de Youyou Tu ...
    From Artemisia annua L. to Artemisinins: The Discovery and Development of Artemisinins and Antimalarial Agents is the first book that systematically introduces the origin and development of artemisinine and artemisinine-based drugs. It includes four distinct sections, including Artemisia annua L., Artemisinin, Dihydroartemisinin, and other artemisinin derivatives. Tu Youyou, the chief inventor of ... Leer más

    $134.99 USD

  • Handbook on the Toxicology of Metals

    Edición de Gunnar F. Nordberg, Bruce A. Fowler, Monica Nordberg ...
    Handbook on the Toxicology of Metals, Fourth Edition bridges the gap between established knowledgebase and new advances in metal toxicology to provide one essential reference for all those involved in the field. This book provides comprehensive coverage of basic toxicological data, emphasizing toxic effects primarily in humans, but also those of animals and biological systems in vitro. The fourth ... Leer más

    $368.99 USD