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  • Chemical Genomics

    Edición de Haian Fu, PhD ...
    Advances in chemistry, biology and genomics coupled with laboratory automation and computational technologies have led to the rapid emergence of the multidisciplinary field of chemical genomics. This edited text, with contributions from experts in the field, discusses the new techniques and applications that help further the study of chemical genomics. The beginning chapters provide an overview of ... Leer más

    $113.99 USD

  • Protein–Protein Interaction Regulators

    Edición de Siddhartha Roy, Haian Fu ...
    Series Libro 78 - Drug Discovery Series
    New genomic information has revealed the crucial role that protein–protein interactions (PPIs) play in regulating numerous cellular functions. Aberrant forms of these interactions are common in numerous diseases and thus PPIs have emerged as a vast class of critical drug targets. Despite the importance of PPIs in biology, it has been extremely challenging to convert targets into therapeutics and ... Leer más

    $247.99 USD

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  • Epigenetics in Cancer

    de Wiley ...
    Series series Life Science Research Fundamentals
    Epigenetics is the study of heritable changes in gene expression or cellular phenotype, caused by mechanisms other than changes in the DNA sequence. Examples include DNA methylation and histone modification. These changes may remain through cell divisions and multiple generations. Epigenetic differences among individuals may account for some of the differences between monozygotic (identical) twins ... Leer más

    $29.00 USD

  • Protein Surface Recognition

    Approaches for Drug Discovery

    A new perspective on the design of molecular therapeutics is emerging. This new strategy emphasizes the rational complementation of functionality along extended patches of a protein surface with the aim of inhibiting protein/protein interactions. The successful development of compounds able to inhibit these interactions offers a unique chance to selectively intervene in a large number of key ... Leer más

    $142.00 USD

  • Structural Aspects Of Protein Synthesis (2nd Edition)

    Series Libro 1 - Series In Structural Biology
    This highly illustrated book provides an up-to-date description of the structure and function of the translation system including ribosomes, tRNAs, translation factors, antibiotics and aminoacyl-tRNA synthetases.Research on translation is undergoing rapid changes and is receiving significant attention as evidenced by the Nobel Prize in Chemistry 2009. The structural research by crystallography and ... Leer más

    $63.99 USD

  • Molecular Analysis and Genome Discovery

    Edición de Ralph Rapley, Stuart Harbron ...
    Molecular Analysis and Genome Discovery, Second Edition is a completely revised and updated new edition of this successful book. The text provides a comprehensive overview of recent developments in the fast moving field of molecular based diagnostics of disease markers. Key concepts and applications are provided alongside practical information on current techniques currently being researched and ... Leer más

    $124.00 USD

  • Peptide-based Drug Discovery

    Challenges and New Therapeutics

    Edición de Ved Srivastava ...
    Series Libro 59 - Drug Discovery Series
    With potentially high specificity and low toxicity, biologicals offer promising alternatives to small-molecule drugs. Peptide therapeutics have again become the focus of innovative drug development efforts backed up by a resurgence of venture funds and small biotechnology companies.What does it take to develop a peptide-based medicine? What are the key challenges and how are they overcome? What ... Leer más

    $225.99 USD

  • Advances in Nucleic Acid Therapeutics

    Edición de Sudhir Agrawal, Michael J Gait ...
    Series Libro 68 - Drug Discovery Series
    The sequencing of the human genome and subsequent elucidation of the molecular pathways that are important in the pathology of disease have provided unprecedented opportunities for the development of new therapeutics. Nucleic acid-based drugs have emerged in recent years to yield extremely promising candidates for drug therapy to a wide range of diseases. Advances in Nucleic Acid Therapeutics is a ... Leer más

    $247.99 USD

  • GPCR Molecular Pharmacology and Drug Targeting

    Shifting Paradigms and New Directions

    Edición de Annette Gilchrist ...
    G protein-coupled receptors (GPCRs) are a large protein family of transmembrane receptors vital in dictating cellular responses. GPCRs are involved in many diseases, but are also the target of around half of all modern medicinal drugs. Shifting Paradigms in G Protein Coupled Receptors takes a look at the way GPCRs are examined today, how they react, how their mutations lead to disease, and the ... Leer más

    $168.00 USD

  • Fundamentals of Advanced Omics Technologies: From Genes to Metabolites

    Series Libro 63 - Comprehensive Analytical Chemistry
    Fundamentals of Advanced Omics Technologies: From Genes to Metabolites covers the fundamental aspects of the new instrumental and methodological developments in omics technologies, including those related to genomics, transcriptomics, epigenetics, proteomics and metabolomics, as well as other omics approaches such as glycomics, peptidomics and foodomics. The principal applications are presented in ... Leer más

    $229.99 USD

  • Disruption of Protein-Protein Interfaces

    In Search of New Inhibitors

    Edición de Stefano Mangani ...
    Series series Chemistry and Material Science (R0)
    "Disruption of Protein-Protein Interfaces" reviews the latest developments and future perspectives in drug discovery at protein-protein interfaces. The authors detail experimental and computational tools to tackle the subject and highlight the contribution of the Italian research community to the field. Evidence shows that blocking or modulating protein-protein interactions might lead to the ... Leer más

    $89.09 USD

  • Targeted Biomarker Quantitation by LC-MS

    Edición de Naidong Weng, Wenying Jian ...
    Series series Wiley Series on Pharmaceutical Science and Biotechnology: Practices, Applications and Methods
    The first book to offer a blueprint for overcoming the challenges to successfully quantifying biomarkers in living organismsThe demand among scientists and clinicians for targeted quantitation experiments has experienced explosive growth in recent years. While there are a few books dedicated to bioanalysis and biomarkers in general, until now there were none devoted exclusively to addressing ... Leer más

    $181.00 USD