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“frank peter theil”

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  • ADME and Translational Pharmacokinetics / Pharmacodynamics of Therapeutic Proteins

    Applications in Drug Discovery and Development

    de Honghui Zhou, Frank-Peter Theil ...
    With an emphasis on the fundamental and practical aspects of ADME for therapeutic proteins, this book helps readers strategize, plan and implement translational research for biologic drugs.Details cutting-edge ADME (absorption, distribution, metabolism and excretion) and PKPD (pharmacokinetic / pharmacodynamics) modeling for biologic drugsCombines theoretical with practical aspects of ADME in ... Leer más

    $133.00 USD

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  • Biological Drug Products

    Development and Strategies

    Edición de Wei Wang, Manmohan Singh ...
    Tested and proven solutions to the challenges of biological drug product developmentBiological drug products play a central role in combating human diseases; however, developing new successful biological drugs presents many challenges, including labor intensive production processes, tighter regulatory controls, and increased market competition. This book reviews the current state of the science, ... Leer más

    $166.00 USD

  • Antibody-Drug Conjugates

    Fundamentals, Drug Development, and Clinical Outcomes to Target Cancer

    Edición de Kenneth J. Olivier Jr., Sara A. Hurvitz ...
    Providing practical and proven solutions for antibody-drug conjugate (ADC) drug discovery success in oncology, this book helps readers improve the drug safety and therapeutic efficacy of ADCs to kill targeted tumor cells.• Discusses the basics, drug delivery strategies, pharmacology and toxicology, and regulatory approval strategies• Covers the conduct and design of oncology clinical trials and ... Leer más

    $138.00 USD

  • Drug Discovery Toxicology

    From Target Assessment to Translational Biomarkers

    Edición de J. Eric McDuffie, Andrew J. Olaharski, Brandon D. Jeffy, Yvonne Will ...
    As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process.• Guides researchers as to what drug safety experiments are both practical and useful• Covers a variety of key topics – safety lead optimization, in vitro-in vivo ... Leer más

    $181.00 USD

  • Biosimilars of Monoclonal Antibodies

    A Practical Guide to Manufacturing, Preclinical, and Clinical Development

    Edición de Cheng Liu, K. John Morrow Jr. ...
    Addressing a significant need by describing the science and process involved to develop biosimilars of monoclonal antibody (mAb) drugs, this book covers all aspects of biosimilar development: preclinical, clinical, regulatory, manufacturing.• Guides readers through the complex landscape involved with developing biosimilar versions of monoclonal antibody (mAb) drugs• Features flow charts, tables, ... Leer más

    $172.00 USD

  • Cardiovascular Diseases

    From Molecular Pharmacology to Evidence-Based Therapeutics

    de Y. Robert Li ...
    Written in an accessible style and consistent format, the book covers both the fundamentals and advances in the pharmacology of cardiovascular drugs, as well as their integrated applications in the management of individual cardiovascular diseases.• Integrates fundamentals and recent advances regarding cardiovascular drugs, blending basic and clinical sciences needed to effectively understand and ... Leer más

    $123.00 USD

  • Nanobiomaterials in Cancer Therapy

    Applications of Nanobiomaterials

    Edición de Alexandru Grumezescu ...
    Nanobiomaterials in Cancer Therapy presents the major applications of nanobiomaterials in oncology, offering an up-to-date overview of the latest research in this field. Utilizing nanobiomaterials, novel therapeutic approaches enable significant improvements in drug-loading capacity, formulation stability and drug efficiency. In this book, leading researchers from around the world share their ... Leer más

    $175.99 USD

  • Translational Biology in Medicine

    de M. Montano ...
    Series series Woodhead Publishing Series in Biomedicine
    The recent emphasis in biomedical research on translational biology and personalized medicine is revolutionizing conceptual and experimental approaches to understanding and improving human health. Translational Biology in Medicine begins with an introduction to experimental model systems for disease, such as cell lines, primary cells, stem cells and animal models for disease, followed by a ... Leer más

    $179.99 USD

  • Attrition in the Pharmaceutical Industry

    Reasons, Implications, and Pathways Forward

    de Alexander Alex, C. John Harris, Dennis A. Smith ...
    With a focus on case studies of R&D programs in a variety of disease areas, the book highlights fundamental productivity issues the pharmaceutical industry has been facing and explores potential ways of improving research effectiveness and efficiency.Takes a comprehensive and holistic approach to the problems and potential solutions to drug compound attritionTackles a problem that adds billions of ... Leer más

    $126.00 USD

  • High-Throughput Screening Methods in Toxicity Testing

    Edición de Pablo Steinberg ...
    Explores the benefits and limitations of the latest high-throughput screening methodsWith its expert coverage of high-throughput in vitro screening methods for toxicity testing, this book makes it possible for researchers to accelerate and streamline the evaluation and risk assessment of chemicals and drugs for toxicity. Moreover, it enables them to comply with the latest standards set forth by ... Leer más

    $152.00 USD

  • Preserving the Promise

    Improving the Culture of Biotech Investment

    de Scott Dessain, Scott E. Fishman ...
    Preserving the Promise: Improving the Culture of Biotech Investment critically examines why most biotech startups fail, as they emerge from universities into an ecosystem that inhibits rather than encourages innovation. This "Valley of Death" squanders our public investments in medical research and with them, the promise of longer and healthier lives. The authors explicate the Translation Gap ... Leer más

    $44.99 USD

  • Rare Earth Elements in Human and Environmental Health

    At the Crossroads Between Toxicity and Safety

    de Giovanni Pagano ...
    This book presents the multifaceted aspects of rare earth elements (REEs), focusing on both their potential benefits and adverse health effects. The adverse impacts of REEs on human and environmental health raise a growing concern not only in the scientific community but also among a number of stakeholders, potentially including students, media workers, and decision makers. The recognized and ... Leer más

    $160.99 USD