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  • BetaSys

    Systems Biology of Regulated Exocytosis in Pancreatic ß-Cells

    Series series Biomedical and Life Sciences (R0)
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  • Next Generation Sequencing Technologies and Challenges in Sequence Assembly

    Series series Biomedical and Life Sciences (R0)
    The introduction of Next Generation Sequencing (NGS) technologies resulted in a major transformation in the way scientists extract genetic information from biological systems, revealing limitless insight about the genome, transcriptome and epigenome of any species. However, with NGS, came its own challenges that require continuous development in the sequencing technologies and bioinformatics ... Leer más

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  • Basics of Bioinformatics

    Lecture Notes of the Graduate Summer School on Bioinformatics of China

    Series series Computer Science (R0)
    This book outlines 11 courses and 15 research topics in bioinformatics, based on curriculums and talks in a graduate summer school on bioinformatics that was held in Tsinghua University. The courses include: Basics for Bioinformatics, Basic Statistics for Bioinformatics, Topics in Computational Genomics, Statistical Methods in Bioinformatics, Algorithms in Computational Biology, Multivariate ... Leer más

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  • Longevity Genes

    A Blueprint for Aging

    Edición de Gil Atzmon, PhD ...
    Series series Biomedical and Life Sciences (R0)
    The release of the complete version of the human genome sequence in 2003 has paved the way for defining gene function and genetic background for phenotypic variation in humans and allowed us to study the aging process in a new light. This new volume results from that research and focuses on the genetic and epigenetic process of aging. While the interpretation of the genome data is still in its ... Leer más

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  • Weighted Network Analysis

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    de Steve Horvath ...
    Series series Biomedical and Life Sciences (R0)
    High-throughput measurements of gene expression and genetic marker data facilitate systems biologic and systems genetic data analysis strategies. Gene co-expression networks have been used to study a variety of biological systems, bridging the gap from individual genes to biologically or clinically important emergent phenotypes. ... Leer más

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  • Soft Computing for Biological Systems

    Series series Biomedical and Life Sciences (R0)
    This book explains how the biological systems and their functions are driven by genetic information stored in the DNA, and their expression driven by different factors. The soft computing approach recognizes the different patterns in DNA sequence and try to assign the biological relevance with available information.The book also focuses on using the soft-computing approach to predict protein ... Leer más

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  • Gene Network Inference

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    Series series Biomedical and Life Sciences (R0)
    This book presents recent methods for Systems Genetics (SG) data analysis, applying them to a suite of simulated SG benchmark datasets. Each of the chapter authors received the same datasets to evaluate the performance of their method to better understand which algorithms are most useful for obtaining reliable models from SG datasets. The knowledge gained from this benchmarking study will ... Leer más

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  • Discriminative Pattern Discovery on Biological Networks

    Series series Computer Science (R0)
    This work provides a review of biological networks as a model for analysis, presenting and discussing a number of illuminating analyses. Biological networks are an effective model for providing insights about biological mechanisms. Networks with different characteristics are employed for representing different scenarios. This powerful model allows analysts to perform many kinds of analyses which ... Leer más

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  • Genome-Wide Prediction and Analysis of Protein-Protein Functional Linkages in Bacteria

    Series series Biomedical and Life Sciences (R0)
    Using genome sequencing, one can predict possible interactions among proteins. There are very few titles that focus on protein-protein interaction predictions in bacteria. The authors will describe these methods and further highlight its use to predict various biological pathways and complexity of the cellular response to various environmental conditions. Topics include analysis of complex genome ... Leer más

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  • MicroRNA Cancer Regulation

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    Series series Biomedical and Life Sciences (R0)
    This edited reflects the current state of knowledge about the role of microRNAs in the formation and progression of solid tumours. The main focus lies on computational methods and applications, together with cutting edge experimental techniques that are used to approach all aspects of microRNA regulation in cancer. We are sure that the emergence of high-throughput quantitative techniques will make ... Leer más

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  • Translational Bioinformatics and Its Application

    Series series Biomedical and Life Sciences (R0)
    This book offers a detailed overview of translational bioinformatics together with real-case applications. Translational bioinformatics integrates the areas of basic bioinformatics, clinical informatics, statistical genetics and informatics in order to further our understanding of the molecular basis of diseases. By analyzing voluminous amounts of molecular and clinical data, it also provides ... Leer más

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  • Genomics and Proteomics for Clinical Discovery and Development

    Edición de György Marko-Varga ...
    Series series Biomedical and Life Sciences (R0)
    The book is intended to be a resource for students as well as scientists in education and for the general public to learn about proteomics and genomics. Chromosomes form the basis for our genetic heritage and are the code for protein synthesis. The Human Genome Map came out in 2002, and the Proteome Sequence Map is under currently being created by a global consortia initiative. Proteome and genome ... Leer más

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