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  • Stem Cell and Gene Therapy for Cardiovascular Disease

    Stem Cell and Gene Therapy for Cardiovascular Disease is a state-of-the-art reference that combines, in one place, the breadth and depth of information available on the topic. As stem cell and gene therapies are the most cutting-edge therapies currently available for patients with heart failure, each section of the book provides information on medical trials from contributors and specialists from ... Leer más

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  • Principles and Practice of Clinical Research

    The third edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory ... Leer más

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  • DNA Repair in Cancer Therapy

    Molecular Targets and Clinical Applications

    Edición de Mark R. Kelley ...
    Cancer therapeutics include an ever-increasing array of tools at the disposal of clinicians in their treatment of this disease. However, cancer is a tough opponent in this battle, and current treatments, which typically include radiotherapy, chemotherapy and surgery, are not often enough to rid the patient of his or her cancer. Cancer cells can become resistant to the treatments directed at them, ... Leer más

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  • Platelets in Thrombotic and Non-Thrombotic Disorders

    Pathophysiology, Pharmacology and Therapeutics: an Update

    Series series Biomedical and Life Sciences (R0)
    This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is ... Leer más

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  • Anticancer Genes

    Edición de Stefan Grimm ...
    Series series Biomedical and Life Sciences (R0)
    This book discusses the emergence of a new class of genes with a specific anticancer activity. These genes, recently defined as “Anticancer Genes”, are reviewed in individual chapters on their mode of action, the specific cell death signals they induce, and the status of attempts to translate them into clinical application.Anticancer Genes provides an overview of this nascent field, its genesis, ... Leer más

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  • Post-Genomic Cardiology

    In this second edition of Post-Genomic Cardiology, developing and new technologies such as translational genomics, next generation sequencing (NGS), bioinformatics, and systems biology in molecular cardiology are assessed in light of their therapeutic potential. As new methods of mutation screening emerge, both for the genome and for the "epigenome, comprehensive understanding of the many ... Leer más

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  • Gene Therapy of Cancer

    Translational Approaches from Preclinical Studies to Clinical Implementation

    Gene therapy as a treatment for cancer is at a critical point in its evolution. Exciting new developments in gene targeting and vector technology, coupled with results from the first generation of preclinical and clinical studies have led to the design and testing of new therapeutic approaches. The Third Edition of Gene Therapy of Cancer provides crucial updates on the basic and applied sciences ... Leer más

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  • Arterial Chemoreceptors in Physiology and Pathophysiology

    Series series Biomedical and Life Sciences (R0)
    Every three years, the International Society for Arterial Chemoreception (ISAC) arranges a Meeting to bring together all of the major International research groups investigating the general topic of oxygen sensing in health and disease, with a prime focus upon systemic level hypoxia and carotid body function. This volume summarises the proceedings of the XIXth meeting of the Society, held in Leeds ... Leer más

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  • Biochemical Basis and Therapeutic Implications of Angiogenesis

    Series series Biomedical and Life Sciences (R0)
    Angiogenesis is a highly complex phenomenon where new blood vessels are formed for the supply of oxygen and nutrients in different organs of the body. It plays a critical role in both physiological processes such as growth and development as well as pathological processes including cancer and different types of tumors. Angiogenesis is also essential for the regeneration and survival of cells in ... Leer más

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  • New Strategies in Stroke Intervention

    Ionic Transporters, Pumps, and New Channels

    Edición de Lucio Annunziato ...
    Series series Biomedical and Life Sciences (R0)
    Ischemic brain damage represents a major source of morbidity and mortality in westernized society and poses a significant financial burden on the health care system. To date, few effective therapies have been realized. Recent evidence, however, suggests that channels, pumps, and ionic exchangers are involved in CNS ischemia and ischemic stroke, but the potential contribution of these channels for ... Leer más

    $98.99 USD

  • Tobacco Smoking Addiction: Epidemiology, Genetics, Mechanisms, and Treatment

    de Ming D. Li ...
    Series series Biomedical and Life Sciences (R0)
    This book provides the most recent knowledge on almost all key aspects of the health impact of tobacco smoking. Its 21 chapters focus on both preclinical and clinical studies. The contents are broad, covering the epidemiology of tobacco smoking; genetic epidemiology; identification of susceptibility genomic regions, genes, and pathways as determined by both human and animal studies; evolutionary ... Leer más

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  • Safety and Efficacy of Gene-Based Therapeutics for Inherited Disorders

    Edición de Nicola Brunetti-Pierri ...
    Series series Biomedical and Life Sciences (R0)
    In this book, leading international experts analyze state-of-the-art advances in gene transfer vectors for applications in inherited disorders and also examine the toxicity profiles of these methods. The authors discuss the strengths and weaknesses of available vectors in the clinical setting, and specifically focus on the challenges and possible solutions that researchers are testing in order to ... Leer más

    $143.99 USD