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  • Epigenetic Regulation in Overcoming Chemoresistance

    Edición de Chunfu Wu, Lihui Wang ...
    Series Libro 16 - Cancer Sensitizing Agents for Chemotherapy
    Epigenetic Regulation in Overcoming Chemoresistance, Volume 19, explains how epigenetic agents can enhance the chemotherapy sensitivity of diverse types of cancers. The book provides a comprehensive delineation and the recent development of the scientific studies on the epigenetic regulation in enhancing chemo-sensitivity. In addition, it discusses several topics such as DNA methyltransferase ... Leer más

    $157.99 USD

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  • DNA Repair of Cancer Stem Cells

    Series series Biomedical and Life Sciences (R0)
    The existence of ‘cancer stem cells’ (CSCs) has been a topic of heated debate for the last few years within the field of cancer biology. Their continuous characterization in a variety of solid tumors has lead to an abundance of evidence supporting their existence. CSCs are believed to be responsible for resistance against conventional treatment regimes of chemotherapy and radiation, ultimately, ... Leer más

    $143.99 USD

  • Pharmacogenomics of Human Drug Transporters

    Clinical Impacts

    Sets the foundation for safer, more effective drug therapiesWith this book as their guide, readers will discover how to apply our current understanding of the pharmacogenomics of drug transporters to advance their own drug discovery and development efforts. In particular, the book explains how new findings in the field now enable researchers to more accurately predict drug interactions and adverse ... Leer más

    $148.00 USD

  • Telomeres, Diet and Human Disease

    Advances and Therapeutic Opportunities

    Edición de Amelia Marti, Guillermo Zalba ...
    The maintenance of telomeres—repetitive sequences at the end of chromosome—is essential to health. Dysfunction in telomere maintenance pathways plays a role in aging, cancer, atherosclerosis and other diseases. This has led to telomere maintenance as a prime target for patient therapies. This book describes the advances in telomere research as it applies to human health and especially how ... Leer más

    $70.99 USD

  • YY1 in the Control of the Pathogenesis and Drug Resistance of Cancer

    A Critical Therapeutic Target

    Edición de Benjamin Bonavida ...
    YY1 Is Pivotal in the Control of the Pathogenesis and Drug Resistance of Cancer: A Critical Therapeutic Target describes the current state-of-the-art of the transcription factor YY1 that is overexpressed in the majority of cancers and a central factor that regulates all of the major features and characteristics of human cancers. This book emphasizes the biochemical, molecular and genetic ... Leer más

    $157.99 USD

  • Targeting Autophagy in Cancer Therapy

    Edición de Jin-Ming Yang ...
    Series series Medicine (R0)
    This volume will detail the current state and perspectives of autophagy-based cancer therapy. Covering a wide range of topics, it will include an overview of autophagy as a therapeutic target in cancer, autophagy modulators as cancer therapeutic agents, implications of micro-RNA-regulated autophagy in cancer therapy, modulation of autophagy through targeting PI3 kinase in cancer therapy, targeting ... Leer más

    $89.99 USD

  • Non-coding RNAs in Colorectal Cancer

    Edición de Ondrej Slaby, George A. Calin ...
    Series series Biomedical and Life Sciences (R0)
    This is the first book to provide a broad framework for obtaining an in depth understanding of the state-of-the-art knowledge on abnormalities of non-coding RNAs found to be associated with colorectal cancer pathogenesis. Readers will discover possible mechanisms underlying the substantial roles played by non-coding RNAs in molecular hallmarks of colorectal cancer.This work further provides the ... Leer más

    $143.09 USD

  • Cancer Stem Cell Markers and Related Network Pathways

    Edición de Shihori Tanabe ...
    Series series Biomedical and Life Sciences (R0)
    This book entitled “Cancer Stem Cell Markers and Related Network Path-ways” is about cancer stem cell (CSC) markers and the molecular network pathways. CSCs play an important role in the cancer drug resistance, metastasis and recurrence. Epithelial-mesenchymal transition (EMT) is closely related to CSC phenotype.This book covers various aspects of the molecular networks related to CSCs including ... Leer más

    $116.99 USD

  • MicroRNAs: Key Regulators of Oncogenesis

    Edición de Sadegh Babashah ...
    Series series Biomedical and Life Sciences (R0)
    Aberrant expression and function of microRNAs (miRNAs) in cancer have added a new layer of complexity to the understanding of development and progression of the disease state. It has been demonstrated that miRNAs have a crucial function in oncogenesis by regulating cell proliferation and apoptosis as oncogenes or tumor suppressors. The expression signatures of miRNAs provide exciting opportunities ... Leer más

    $143.09 USD

  • Non-Canonical Autophagy

    Mechanisms and Pathophysiological Implications

    Edición de Giulia Petroni, Lorenzo Galluzzi ...
    Non-canonical Autophagy: Mechanisms and Pathophysiological Implications outlines the differences between 'canonical' and 'non-canonical' forms of autophagy, highlighting the discoveries concerning the molecular mechanisms underlying these unconventional forms of autophagy and the advancements in pathophysiological features of 'non-canonical' autophagy. The book discusses all forms of 'non ... Leer más

    $157.99 USD

  • Autophagy in tumor and tumor microenvironment

    Edición de Sujit Kumar Bhutia ...
    Series series Biomedical and Life Sciences (R0)
    This book deals with the paradoxical role of autophagy in tumor suppression and tumor promotion in cancer cells. Autophagy plays opposing, context-dependent roles in tumors; accordingly, strategies based on inhibiting or stimulating autophagy could offer as potential cancer therapies.The book elucidates the physiological role of autophagy in modulating cancer metastasis, which is the primary cause ... Leer más

    $89.99 USD

  • The Long and Short Non-coding RNAs in Cancer Biology

    Edición de Erwei Song ...
    Series series Biomedical and Life Sciences (R0)
    The book conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferation, ... Leer más

    $143.99 USD