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  • Molecular Genetics of Pediatric Orthopaedic Disorders

    Edición de Carol A. Wise, Jonathan J. Rios ...
    Series series Biomedical and Life Sciences (R0)
    In the past two decades we have seen a surge forward in understanding the genetics and biochemistry underlying many pediatric orthopaedic disorders. A few projects have even progressed into the realm of clinical trials that are primarily aimed at controlling progressive disease. Meanwhile, genomic technology development has outpaced expectations and is enabling gene discovery for disorders that ... Leer más

    $89.99 USD

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  • Introduction to Molecular Medicine

    Series series Medicine (R0)
    How will increased understanding of the human genome affect our ability to diagnose and treat disease? The subject of recombinant DNA technology is no longer limited to the research laboratory; it is being discussed in ever-widening medical circles. Introduction to Molecular Medicine is especially written for the physician who is not a genetics expert but wishes to understand this new science and ... Leer más

    $80.09 USD

  • Gene Therapy in Inflammatory Diseases

    Series series Progress in Inflammation Research
    Gene therapy for inflammatory diseases is a new , burgeoning field of medicine. Edited by the undisputed pioneers of this area of research, this volume is the first devoted to its topic. It contains thirteen chapters, each written by leaders in their respective fields, that summarize the state of the art in developing novel, gene based treatments for inflammatory diseases. As well as providing an ... Leer más

    $143.99 USD

  • Molecular Genetics of Inflammatory Bowel Disease

    Edición de Mauro D'Amato, John D Rioux ...
    Series series Biomedical and Life Sciences (R0)
    Research in Crohn’s disease (CD) and ulcerative colitis (UC), together known as the inflammatory bowel diseases (IBD), has truly seen a revolution in the last 5-10 years. This book examines how these genetic discoveries have led to the identification of biological functions not previously associated with IBD pathophysiology (e.g. autophagy), how multiple genetic risk factors for IBD converge on ... Leer más

    $143.99 USD

  • Cystogenesis

    Edición de Jong Hoon Park, Curie Ahn ...
    Series series Biomedical and Life Sciences (R0)
    Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating ... Leer más

    $89.09 USD

  • Dupuytren Disease and Related Diseases - The Cutting Edge

    Series series Medicine (R0)
    In this book, leading international experts showcase the latest advances in research into Dupuytren disease and its clinical management. The coverage spans all relevant specialties, including cell biology, biomechanics, genomics, surgery, pharmacotherapy, and radiotherapy. The opening sections address epidemiology, cellular and extracellular events, and genetics. Treatment by means of collagenase ... Leer más

    $98.09 USD

  • Safety and Efficacy of Gene-Based Therapeutics for Inherited Disorders

    Edición de Nicola Brunetti-Pierri ...
    Series series Biomedical and Life Sciences (R0)
    In this book, leading international experts analyze state-of-the-art advances in gene transfer vectors for applications in inherited disorders and also examine the toxicity profiles of these methods. The authors discuss the strengths and weaknesses of available vectors in the clinical setting, and specifically focus on the challenges and possible solutions that researchers are testing in order to ... Leer más

    $143.09 USD

  • Chemical Biology of Nucleic Acids

    Fundamentals and Clinical Applications

    Series series Biomedical and Life Sciences (R0)
    This volume contains 29 engrossing chapters contributed by worldwide, leading research groups in the field of chemical biology. Topics include pre-biology; the establishment of the genetic code; isomerization of RNA; damage of nucleobases in RNA; the dynamic structure of nucleic acids and their analogs in DNA replication, extra- and intra-cellular transport; molecular crowding by the use of ionic ... Leer más

    $188.99 USD

  • Cancer Stem Cells: Emerging Concepts and Future Perspectives in Translational Oncology

    Edición de Sadegh Babashah ...
    Series series Biomedical and Life Sciences (R0)
    The concept of cancer stem cells has great clinical implications. This is due to the fact that small subpopulations of these cells have been identified in a variety of neoplastic conditions ranging from solid tumors to liquid malignancies. Although there are some huge gaps in our current understanding of the role played by cancer stem cells in cancer biology, a growing body of evidence provides ... Leer más

    $143.09 USD

  • Histone Deacetylases: the Biology and Clinical Implication

    Edición de Tso-Pang Yao, Edward Seto ...
    Series series Biomedical and Life Sciences (R0)
    The book highlights work from many different labs that taught us abnormal HDACs potentially contribute to the development or progression of many human diseases including immune dysfunctions, heart disease, cancer, memory impairment, aging, and metabolic disorders. ... Leer más

    $287.99 USD

  • Next Generation Sequencing Technologies in Medical Genetics

    Series series Biomedical and Life Sciences (R0)
    This book introduces readers to Next Generation Sequencing applications in medical genetics. The authors discuss the direct application of next-generation sequencing to medicine, specifically, laboratory medicine or molecular diagnostics. The first part of the book contains chapters on sanger sequencing, NGS technologies, targeted-amplification and capture, and exome sequencing. The second part of ... Leer más

    $71.99 USD