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  • Neuroscience Research and Textbook

    3

    Neuroscience is a fascinating field that explores the inner workings of the brain and nervous system. In this book, readers will delve into the complex world of neuroscience and discover how it relates to human behavior, cognition, and emotion.Starting with the basics of brain structure and function, the book provides an introduction to the major topics in neuroscience. ... Leer más

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  • Genome Editing in Neurosciences

    Series series Research and Perspectives in Neurosciences
    This book is open access under a CC BY 4.0 license.CRISPR-Cas9 is a rapid, efficient, versatile and relatively cheap method for dissecting the molecular pathways that are the basis of life, as well as for investigating and potentially rectifying faults in these pathways that result in disease.This book reviews how CRISPR-Cas9 and other genome editing techniques are advancing our understanding of ... Leer más

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  • Medicinal Chemistry Approaches to Personalized Medicine

    Series Libro 59 - Methods & Principles in Medicinal Chemistry
    Edited by two renowned medicinal chemists who have pioneered the development of personalized therapies in their respective fields, this authoritative analysis of what is already possible is the first of its kind, and the only one to focus on drug development issues.Numerous case studies from the first generation of "personalized drugs" are presented, highlighting the challenges and opportunities ... Leer más

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  • The Molecular and Cellular Basis of Neurodegenerative Diseases

    Underlying Mechanisms

    Edición de Michael S. Wolfe ...
    The Molecular and Cellular Basis of Neurodegenerative Diseases: Underlying Mechanisms presents the pathology, genetics, biochemistry and cell biology of the major human neurodegenerative diseases, including Alzheimer's, Parkinson's, frontotemporal dementia, ALS, Huntington's, and prion diseases. Edited and authored by internationally recognized leaders in the field, the book's chapters explore ... Leer más

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  • Handbook of Epigenetics

    The New Molecular and Medical Genetics

    Edición de Trygve O. Tollefsbol ...
    Handbook of Epigenetics: The New Molecular and Medical Genetics, Third Edition provides a comprehensive analysis of epigenetics, from basic biology to clinical application. This new edition has been fully revised to cover the latest and evolving topics in epigenetics, with chapters updated and new chapters added on topics such as single-cell epigenetics, DNA methylation clocks in age-related ... Leer más

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  • Mitochondrial Diseases

    de Wiley ...
    Series series Life Science Research Fundamentals
    This collection of reviews and protocols provides the reader with an introduction to the current state of knowledge on how various diseases are related to mitochondrial dysfunction. Mitochondria contain their own genome, a small, circular double-stranded DNA (mtDNA), and alterations in mtDNA may play an important role in the multistep carcinogenesis of at least some types of human cancer. In ... Leer más

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  • PAKs, RAC/CDC42 (p21)-activated Kinases

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    Edición de Hiroshi Maruta ...
    This book covers a variety of cutting-edge basic and clinical PAK research ranging from laboratory benches to hospital beds. The goal of this book is to inspire not only biomedical research scientists and university students, but also a variety of patients who suffer from PAK-dependent diseases and clinical doctors who try to cure or delay these PAK-dependent diseases.This book consists of 9 ... Leer más

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  • Handbook of Epigenetics

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    Edición de Trygve O. Tollefsbol ...
    Handbook of Epigenetics: The New Molecular and Medical Genetics, Second Edition, provides a comprehensive analysis of epigenetics, from basic biology, to clinical application. Epigenetics is considered by many to be the new genetics in that many biological phenomena are controlled, not through gene mutations, but rather through reversible and heritable epigenetic processes. These epigenetic ... Leer más

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  • Understanding PTMs in Neurodegenerative Diseases

    Edición de Victor Corasolla Carregari ...
    Series series Biomedical and Life Sciences (R0)
    This new volume, a part of the Proteomics, Metabolomics, Interactomics and Systems Biology series, will explain how proteomic studies of post-translational modifications (PTMs) can be applied to neurodegenerative diseases and relevant studies. The goal of the book is to increase awareness among researchers about how PTMs may be helpful in understanding mechanisms in various neurodegenerative ... Leer más

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  • Advances in Stem Cell Aging

    de S. Pahernik ...
    Adult stem cells are present in most postnatal tissues of mammals. Tissues with high rates of cell turnover depend on the functional capacity of stem cells for lifelong maintenance of tissue homeostasis. Adult stem cells are also required for the regeneration of tissues in response to injury as in, for example, the regeneration of skeletal muscle. In addition to its function in tissue homeostasis ... Leer más

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  • Long Non Coding RNA Biology

    Edición de M.R.S. Rao ...
    Series series Biomedical and Life Sciences (R0)
    This contributed volume offers a comprehensive and detailed overview of the various aspects of long non-coding RNAs and discusses their emerging significance. Written by leading experts in the field, it motivates young researchers around the globe, and offers graduate and postgraduate students fascinating insights into genes and their regulation in eukaryotes and higher organisms. ... Leer más

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