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1 - 12 de 12 resultados para “adrian hobson”
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  • The Medicinal Chemistry of Glucocorticoid Receptor Modulators

    de Adrian Hobson ...
    Series series Chemistry and Material Science (R0)
    This book covers the design and development of glucocorticoid receptor modulators (GRM) from cortisol to antibody-drug conjugate payloads over the last 70 years. The author starts with an introduction to the background of glucocorticoid receptor modulators as potential therapeutic modalities. This is followed by seven chapters in which he collates and discusses the medicinal chemistry journey of ... Leer más

    $44.99 USD

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  • Tumor Microenvironment

    Edición de Dietmar W. Siemann ...
    The microenvironment in which a tumor originates plays a critical role in its initiation and progression. Tumor Microenvironment reviews the importance of tumor microenvironment in cancer management. Particular emphasis is placed on discussing how the unique characteristics of the tumor microenvironment not only impact disease progression and response to conventional anticancer therapies, but have ... Leer más

    $148.00 USD

  • Platelet Proteomics

    Principles, Analysis, and Applications

    Edición de Yotis Senis, Ángel García-Alonso ...
    Series Libro 47 - Wiley Series on Mass Spectrometry
    The purpose of the book is to introduce platelets, and their functional role in thrombotic and cardiovascular disease, justifying the relevance of platelet proteomics research. Focus then shifts to the recent developments on mass spectrometry (MS)-based proteomics. This chapter shows potential applications for platelet proteomics not yet carried out. It includes examples of post-translational ... Leer más

    $107.00 USD

  • Monoclonal Antibody and Peptide-Targeted Radiotherapy of Cancer

    Edición de Raymond M. Reilly ...
    Oncology Book of 2011, British Medical Association's Medical Book AwardsAwarded first prize in the Oncology category at the 2011 BMA Medical Book Awards, Monoclonal Antibody and Peptide-Targeted Radiotherapy of Cancer helps readers understand this hot pharmaceutical field with up-to-date developments. Expert discussion covers a range of diverse topics associated with this field, including the ... Leer más

    $168.00 USD

  • Prodrugs and Targeted Delivery

    Towards Better ADME Properties

    de Raimund Mannhold, Hugo Kubinyi, Gerd Folkers ...
    Series Libro 47 - Methods & Principles in Medicinal Chemistry
    This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational design of prodrugs, beginning at the early stages of the development process, as well as discussing organ- and site-selective prodrugs ... Leer más

    $166.00 USD

  • Analogue-based Drug Discovery II

    Edición de C. Robin Ganellin, János Fischer ...
    Born out of a project of the IUPAC's committee on Medicinal Chemistry and Drug Development, this reference addresses past and current strategies for successful drug analog development, extending the previously published volume by nine new analog classes and eight case studies. Like its precursor, this volume also contains a general section discussing universally applicable strategies for analog ... Leer más

    $212.00 USD

  • Handbook Of Porphyrin Science: With Applications To Chemistry, Physics, Materials Science, Engineering, Biology And Medicine (Volumes 26-30)

    de Gloria C Ferreira ...
    Series Libro 6 - Handbook Of Porphyrin Science
    This is the sixth set of Handbook of Porphyrin Science.This 5-volume set provides a comprehensive review of the most up-to-date research on porphyrin, heme and chlorophyll biochemistry, as well as applications to biomedicine and bio-inspired energy. In-depth coverage of topics along with perspectives on outstanding questions and future research directions by the authors make these volumes an ... Leer más

    $1,331.99 USD

  • Case Studies in Modern Drug Discovery and Development

    Edición de Xianhai Huang, Robert G. Aslanian ...
    Learn why some drug discovery and development efforts succeed . . . and others failWritten by international experts in drug discovery and development, this book sets forth carefully researched and analyzed case studies of both successful and failed drug discovery and development efforts, enabling medicinal chemists and pharmaceutical scientists to learn from actual examples. Each case study ... Leer más

    $133.00 USD

  • Drug Delivery in Oncology

    From Basic Research to Cancer Therapy

    Edición de Felix Kratz, Peter Senter, Henning Steinhagen ...
    In this first authoritative overview on modern cancer chemotherapy 121 international specialists have contributed their experience and recent data for what is likely to become the gold standard in the field.The authors summarize knowledge gained over the past decade, from basic concepts to successful applications in the clinic, covering active and passive targeting strategies as well as tissue ... Leer más

    $549.00 USD

  • Peptide-based Drug Discovery

    Challenges and New Therapeutics

    Edición de Ved Srivastava ...
    Series Libro 59 - Drug Discovery Series
    With potentially high specificity and low toxicity, biologicals offer promising alternatives to small-molecule drugs. Peptide therapeutics have again become the focus of innovative drug development efforts backed up by a resurgence of venture funds and small biotechnology companies.What does it take to develop a peptide-based medicine? What are the key challenges and how are they overcome? What ... Leer más

    $225.99 USD

  • Therapeutic Proteins

    Strategies to Modulate Their Plasma Half-lives

    Edición de Roland Kontermann ...
    For this ready reference, the internationally renowned authority in the field, Roland Kontermann, has assembled a team of outstanding contributors from industry and academia to convey the worldwide knowledge on modifying therapeutic proteins in order to optimize their pharmacological potential. The result is a comprehensive work covering all approaches and aspects of the topic in one handy volume, ... Leer más

    $117.00 USD

  • Drug Delivery

    Edición de Monika Schäfer-Korting ...
    Series series Biomedical and Life Sciences (R0)
    In the view of most experts pharmacology is on drugs, targets, and actions. In the context the drug as a rule is seen as an active pharmaceutical ingredient and not as a complex mixture of chemical entities of a well defined structure. Today, we are becoming more and more aware of the fact that delivery of the active compound to the target site is a key. The present volume gives a topical overview ... Leer más

    $287.09 USD