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Showing 1 - 12 of 12 results for “toshiro tango”
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  • Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials

    by Toshiro Tango ...
    Series series Chapman & Hall/CRC Biostatistics Series
    Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials is the first book focused on the application of generalized linear mixed models and its related models in the statistical design and analysis of repeated measures from randomized controlled trials. The author introduces a new repeated measures design called S:T design combined with mixed models as a ... Read more

    $68.99 USD

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  • Biostatistics and Epidemiology

    A Primer for Health and Biomedical Professionals

    by Sylvia Wassertheil-Smoller, Jordan Smoller ...
    Since the publication of the first edition, Biostatistics and Epidemiology has attracted loyal readers from across specialty areas in the biomedical community. Not only does this textbook teach foundations of epidemiological design and statistical methods, but it also includes topics applicable to new areas of research. Areas covered in the fourth edition include a new chapter on risk prediction, ... Read more

    $80.99 USD

  • Nonclinical Statistics for Pharmaceutical and Biotechnology Industries

    by Max Kuhn, Ian Peers, Stan Altan ...
    Series series Mathematics and Statistics (R0)
    This book serves as a reference text for regulatory, industry and academic statisticians and also a handy manual for entry level Statisticians. Additionally it aims to stimulate academic interest in the field of Nonclinical Statistics and promote this as an important discipline in its own right. This text brings together for the first time in a single volume a comprehensive survey of methods ... Read more

    $170.09 USD

  • Applied Survival Analysis Using R

    by Dirk F. Moore ...
    Series series Mathematics and Statistics (R0)
    Applied Survival Analysis Using R covers the main principles of survival analysis, gives examples of how it is applied, and teaches how to put those principles to use to analyze data using R as a vehicle. Survival data, where the primary outcome is time to a specific event, arise in many areas of biomedical research, including clinical trials, epidemiological studies, and studies of animals. Many ... Read more

    $53.99 USD

  • Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models

    by Joel S. Owen, Jill Fiedler-Kelly ...
    This book provides a user-friendly, hands-on introduction to the Nonlinear Mixed Effects Modeling (NONMEM) system, the most powerful tool for pharmacokinetic / pharmacodynamic analysis.• Introduces requisite background to using Nonlinear Mixed Effects Modeling (NONMEM), covering data requirements, model building and evaluation, and quality control aspects• Provides examples of nonlinear modeling ... Read more

    $102.00 USD

  • Biostatistics with R

    An Introduction to Statistics Through Biological Data

    by Babak Shahbaba ...
    Series series Mathematics and Statistics (R0)
    Biostatistics with R is designed around the dynamic interplay among statistical methods, their applications in biology, and their implementation. The book explains basic statistical concepts with a simple yet rigorous language. The development of ideas is in the context of real applied problems, for which step-by-step instructions for using R and R-Commander are provided. Topics include data ... Read more

    $80.99 USD

  • Bayesian Designs for Phase I-II Clinical Trials

    by Ying Yuan, Hoang Q. Nguyen, Peter F. Thall ...
    Series series Chapman & Hall/CRC Biostatistics Series
    Reliably optimizing a new treatment in humans is a critical first step in clinical evaluation since choosing a suboptimal dose or schedule may lead to failure in later trials. At the same time, if promising preclinical results do not translate into a real treatment advance, it is important to determine this quickly and terminate the clinical evaluation process to avoid wasting resources.Bayesian ... Read more

    $61.99 USD

  • Benefit-Risk Assessment Methods in Medical Product Development

    Bridging Qualitative and Quantitative Assessments

    Edited by Qi Jiang, Weili He ...
    Series series Chapman & Hall/CRC Biostatistics Series
    Guides You on the Development and Implementation of B–R EvaluationsBenefit–Risk Assessment Methods in Medical Product Development: Bridging Qualitative and Quantitative Assessments provides general guidance and case studies to aid practitioners in selecting specific benefit–risk (B–R) frameworks and quantitative methods. Leading experts from industry, regulatory agencies, and academia present ... Read more

    $68.99 USD

  • Practical Considerations for Adaptive Trial Design and Implementation

    Edited by Weili He, Olga M. Kuznetsova, José Pinheiro ...
    Series series Mathematics and Statistics (R0)
    This edited volume is a definitive text on adaptive clinical trial designs from creation and customization to utilization. As this book covers the full spectrum of topics involved in the adaptive designs arena, it will serve as a valuable reference for researchers working in industry, government and academia. The target audience is anyone involved in the planning and execution of clinical trials, ... Read more

    $170.99 USD

  • The Design and Statistical Analysis of Animal Experiments

    by Simon T. Bate, Robin A. Clark ...
    Written for animal researchers, this book provides a comprehensive guide to the design and statistical analysis of animal experiments. It has long been recognised that the proper implementation of these techniques helps reduce the number of animals needed. By using real-life examples to make them more accessible, this book explains the statistical tools employed by practitioners. A wide range of ... Read more

    $63.99 USD

  • Quick Guide to Good Clinical Practice

    How to Meet International Quality Standard in Clinical Research

    by Cemal Cingi, Nuray Bayar Muluk ...
    Series series Medicine (R0)
    This brand-new book offers a reference guide to understanding and applying the rules for properly conducting clinical trials to meet the international quality standard – Good Clinical Practice – provided by the International Conference on Harmonization (ICH).The work offers an updated perspective on the clinical research landscape within the context of the clinical trial regulatory frameworks in ... Read more

    $89.09 USD

  • Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials

    Edited by John O'Quigley, Alexia Iasonos, Björn Bornkamp ...
    Series series Chapman & Hall/CRC Handbooks of Modern Statistical Methods
    Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials gives a thorough presentation of state-of-the-art methods for early phase clinical trials. The methodology of clinical trials has advanced greatly over the last 20 years and, arguably, nowhere greater than that of early phase studies. The need to accelerate drug development in a rapidly evolving context of targeted ... Read more

    $104.99 USD