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Showing 1 - 12 of 12 results for “tilman grune”
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  • The Proteasomal System in Aging and Disease

    by Tilman Grune ...
    Series Book 109 - Progress in Molecular Biology and Translational Science
    This volume of Progress in Molecular Biology and Translational Science discusses cutting-edge research of proteasomes and proteasome-associated proteins and cellular systems. The volume is split into two sections. The first part discusses the current knowledge of the structure, function, and regulation of the proteasomal system. The second part describes the role of the proteasome in aging and ... Read more

    $149.39 USD

  • Protein Oxidation and Aging

    by Tilman Grune, Betul Catalgol, Tobias Jung, Vladimir Uversky ...
    Series Book 15 - Wiley Series in Protein and Peptide Science
    Reviews our current understanding of the role of protein oxidation in aging and age-related diseasesProtein oxidation is at the core of the aging process. Setting forth a variety of new methods and approaches, this book helps researchers conveniently by exploring the aging process and developing more effective therapies to prevent or treat age-related diseases. There have been many studies ... Read more

    $152.00 USD

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  • Nutrition in Epigenetics

    Edited by Mihai D. Niculescu, Paul Haggarty ...
    The study of epigenetics, or how heritable changes in gene expression are regulated without modifying the coding DNA sequence, has become an increasingly important field of study in recent years. Rapid developments in our understanding of the way in which gene function is modulated by the environment has revolutionized the way we think about human development and health. Nutrition in Epigenetics ... Read more

    $209.00 USD

  • Protein Misfolding Diseases

    Current and Emerging Principles and Therapies

    Edited by Marina Ramirez-Alvarado, Jeffery W. Kelly, Christopher M. Dobson ...
    Series Book 14 - Wiley Series in Protein and Peptide Science
    An increasingly aging population will add to the number of individuals suffering from amyloid. Protein Misfolding Diseases provides a systematic overview of the current and emerging therapies for these types of protein misfolding diseases, including Alzheimer's, Parkinson's, and Mad Cow. The book emphasizes therapeutics in an amyloid disease context to help students, faculty, scientific ... Read more

    $218.00 USD

  • Metabolism of Drugs and Other Xenobiotics

    Edited by Pavel Anzenbacher, Ulrich M. Zanger ...
    A practice-oriented desktop reference for medical professionals, toxicologists and pharmaceutical researchers, this handbook providessystematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part comprehensively reviewsthe main enzyme systems involved in biotransformation and how they are orchestrated in the body, while parts two to four cover ... Read more

    $209.00 USD

  • Amino Acid Metabolism

    by David A. Bender ...
    Amino Acid Metabolism, 3rd Edition covers all aspects of the biochemistry and nutritional biochemistry of the amino acids. Starting with an overview of nitrogen fixation and the incorporation of inorganic nitrogen into amino acids, the book then details other major nitrogenous compounds in micro-organisms, plants and animals. Contents include a discussion of the catabolism of amino acids and other ... Read more

    $125.00 USD

  • Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants

    Edited by Yvonne Will, James A. Dykens ...
    Developed as a one-stop reference source for drug safety and toxicology professionals, this book explains why mitochondrial failure is a crucial step in drug toxicity and how it can be avoided.• Covers both basic science and applied technology / methods• Allows readers to understand the basis of mitochondrial function, the preclinical assessments used, and what they reveal about drug effects• ... Read more

    $334.00 USD

  • Medicinal Chemistry of Anticancer Drugs

    by Carmen Avendaño, J. Carlos Menéndez ...
    Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research ... Read more

    $179.99 USD

  • Reactive Drug Metabolites

    by Deepak Dalvie, R. Scott Obach, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers, Dennis A. Smith, Amit S. Kalgutkar ...
    Series Book 55 - Methods & Principles in Medicinal Chemistry
    Closing a gap in the scientifi c literature, this first comprehensive introduction to the topic is based on current best practice in one of the largestpharmaceutical companies worldwide. The first chapters trace the development of our understanding of drug metabolite toxicity, covering basic concepts and techniques in the process, while the second part details chemical toxicophores that are prone ... Read more

    $150.00 USD

  • Mitochondria and Cancer

    Edited by Keshav Singh, Leslie Costello ...
    Nearly a century of scientific research has revealed that mitochondrial dysfunction is one of the most common and consistent phenotypes of cancer cells. A number of notable differences in the mitochondria of normal and cancer cells have been described. These include differences in mitochondrial metabolic activity, molecular composition of mitochondria and mtDNA sequence, as well as in alteration ... Read more

    $134.99 USD

  • Cytochrome P450

    Structure, Mechanism, and Biochemistry

    Edited by Paul R. Ortiz de Montellano ...
    Series series Medicine (R0)
    This authoritative Fourth Edition summarizes the advances of the past decade concerning the structure, mechanism, and biochemistry of cytochrome P450 enzymes, with sufficient coverage of earlier work to make each chapter a comprehensive review of the field. Thirteen chapters are divided into two detailed volumes, the first covering the fundamentals of cytochrome P450 biochemistry, as well as the ... Read more

    $395.09 USD

  • The AH Receptor in Biology and Toxicology

    by Raimo Pohjanvirta ...
    This book provides a thorough and up-to-date overview of the aryl hydrocarbon receptor (AHR) and its unique dual role in toxicology and biology. The coverage includes epigenetic mechanisms, gene expression, reproductive and developmental toxicity, signal transduction, and transgenic animal models. Featuring an internationally recognized team of authors at the forefront of AHR research, this ... Read more

    $158.00 USD