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  • Non-coding RNAs in the Vasculature

    Series series Biomedical and Life Sciences (R0)
    This volume describes important functions and roles of micro RNAs in the vasculature in health, disease, therapeutics and diagnostics. It shows how miRNAs can be used to improve stem cell-based regenerative therapies of cardiovascular diseases; further the role of miRNAs as regulators in lipoprotein metabolism in the liver and reverse cholesterol transport is depicted, as well as their ... Read more

    $89.09 USD

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  • Laron Syndrome - From Man to Mouse

    Lessons from Clinical and Experimental Experience

    Edited by Zvi Laron, J. Kopchick ...
    Series series Medicine (R0)
    Laron syndrome (LS), or primary growth hormone (GH) insensitivity, was first described in 1966. Since then, many patients worldwide have been diagnosed with LS, which involves defects in the GH receptor that cause combined congenital deficiency of GH and IGF-I activities. In this comprehensive book the authors draw upon 50 years of multidisciplinary clinical and investigative follow-up of the ... Read more

    $215.09 USD

  • Impact of Sleep and Sleep Disturbances on Obesity and Cancer

    Series series Biomedical and Life Sciences (R0)
    Sleep has recently been recognized as a critical determinant of energy balance regulating, restoration and repair of many of the physiologic and psychologic processes involved in modulating energy intake and utilization. In addition to having an impact on obesity, sleep abnormalities, both quantitative and qualitative, have now been shown to have significant effects on obesity associated ... Read more

    $89.09 USD

  • Introduction to Molecular Medicine

    How will increased understanding of the human genome affect our ability to diagnose and treat disease? The subject of recombinant DNA technology is no longer limited to the research laboratory; it is being discussed in ever-widening medical circles. Introduction to Molecular Medicine is especially written for the physician who is not a genetics expert but wishes to understand this new science and ... Read more

    $80.09 USD

  • Molecular mechanisms and physiology of disease

    Implications for Epigenetics and Health

    Series series Biomedical and Life Sciences (R0)
    In a simplified form, epigenetics refers to heritable changes in phenotype that are not due to changes in the underlying DNA sequence. In this book, epigenetic mechanisms of regulation and dysregulation in health and disease are explored in great depth. Detailed chapters on epigenetic processes including DNA methylation and chromatin post-translational modifications including potential ... Read more

    $188.09 USD

  • Methods in Endothelial Cell Biology

    Edited by Hellmut G. Augustin ...
    Series series Biomedical and Life Sciences (R0)
    Endothelial cell biology has developed into a vibrant discipline and has become a critical instrument to study several disease processes on the cellular and molecular level. It is now widely recognized that dysfunctions of normal endothelial cell homeostasis are involved in some of the most important human diseases, including ischemic heart diseases, hypertension, atherosclerosis, tumors, diabetes ... Read more

    $188.09 USD

  • Molecular and Cellular Biology of Platelet Formation

    Implications in Health and Disease

    This book gives a comprehensive insight into platelet biogenesis, platelet signal transduction, involvement of platelets in disease, the use of diverse animal models for platelet research and future perspectives in regard to platelet production and gene therapy. Being written by international experts, the book is a concise state-of-the art work in the field of platelet biogenesis, biology and ... Read more

    $206.99 USD

  • Advances in Down Syndrome Research

    Edited by Gert Lubec ...
    Series series Medicine (R0)
    "Advances in Down Syndrome Research” represents updated research in several areas of Down Syndrome (DS). A new promising animal model of DS is reported and this opens new opportunities to study pathomechanisms and pharmacological approaches as it is more than difficult to carry out studies in humans and the clinical features are highly variable. In terms of biology, cell cycle and stem cell ... Read more

    $143.09 USD

  • Arterial Stiffness

    Implications and Interventions

    Series series Biomedical and Life Sciences (R0)
    Arterial stiffness is an emerging risk factor with important implications for cardiovascular disease risk. Herein, we concisely summarize the physiological and pathophysiological aspects of arterial stiffening, and highlight the importance of increased arterial stiffness for future cardiovascular events. Factors contributing to increased arterial stiffness such as advancing age, obesity, race, sex ... Read more

    $49.49 USD

  • Epigenetics in Cardiac Disease

    Series Book 1 - Cardiac and Vascular Biology
    This book describes important advances in our understanding of how environmental conditions affect cardiac gene expression through epigenetic mechanisms. Further, it discusses the roles of chromatin modifications (in particular DNA methylation and histone modifications) and of chromatin regulators in the context of cardiac diseases. The book provides readers with an overview of our current ... Read more

    $143.99 USD