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  • Gasotransmitters: Physiology and Pathophysiology

    Series series Biomedical and Life Sciences (R0)
    Since the epochal discovery of the radical and highly toxic gas nitric oxide (NO) as a signaling molecule, two other no less toxic gases – carbon monoxide (CO) and hydrogen sulfide (H2S) – have been found to also be involved in a plethora of physiological and pathophysiological functions. The gases termed gasotransmitters play an increasingly important role in understanding how signalling into and ... Read more

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    Series series Medicine (R0)
    This first volume in a projected series contains the proceedings of the first of the Keio University International Symposia for Life Sciences and Medicine under the sponsorship of the Keio University Medical Science Fund. As stated in the address by the President of Keio University at the opening of the 1996 symposium, the fund of Dr. Mitsunada Sakaguchi. The Keio was established by the generous ... Read more

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  • Growth Hormone II

    Basic and Clinical Aspects

    Series series Serono Symposia USA
    This book is a compendium of proceedings from the Symposium on Growth Hormone II: Basic and Clinical Aspects. The intent of the sym posium was to review current aspects of the rapidly expanding science of growth hormone (GH) neuroendocrinology, especially those develop ments that occurred since our last meeting in 1985. The meeting was timely since there have been many new and exciting ... Read more

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  • The Cadherin Superfamily

    Key Regulators of Animal Development and Physiology

    Series series Biomedical and Life Sciences (R0)
    This book presents an overview of the entire field of cadherin research and provides the current basic concept of cadherins. Cadherins have been widely accepted as key regulators of animal development and physiological functions, and it also has become clear that they play essential roles in various human diseases. With contributions by leading scientists, the book covers various aspects of the ... Read more

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  • The Anatomy of Manual Dexterity

    The New Connectivity of the Primate Sensorimotor Thalamus and Cerebral Cortex

    Series Book 133 - Advances in Anatomy, Embryology and Cell Biology
    1 Purpose and Plan of This Review This review is focused on the topography and connections of some of the neuron populations that determine the manual dexterity of the macaque monkey. The populations selected for examination are the following: 1. The corticospinal neuron populations 2. The thalamocortical and corticothalamic neuron populations associated with the sensorimotor cortex 3. The ... Read more

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  • Oxidative Neural Injury

    Edited by Sigrid C. Veasey ...
    Series series Biomedical and Life Sciences (R0)
    Twenty-five years ago, Earl R. Stadtman, PhD discovered that specific enzymes regulating metabolism can be inactivated by oxidation [1]. He later showed that age-related oxidative modification contributes, at least in part, to age-related loss of function of the enzymes [2, 3]. Dr. Stadtman broke the ground for a new field of study to discover how oxidative stress contributes in significant ways ... Read more

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  • The Catecholaminergic Innervation of the Rat Amygdala

    by Esther Asan ...
    Series Book 142 - Advances in Anatomy, Embryology and Cell Biology
    Experimental evidence indicated that catecholamines are able to modulate information processing in the amygdaloid complex. The present study provides a detailed documentation of ultrastructural and neurochmical characteristics of dopaminergic, noradrinergic, and adrenergic afferent fibers and of their target structures in central, basal and intercalated amygdaloid nuclei. ... Read more

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  • Microglia in the Regenerating and Degenerating Central Nervous System

    Edited by Wolfgang J. Streit ...
    Over the past decade, the study of microglial cells has gained increasing importance, in particular for those working in the fields of degeneration and regeneration. Microglia in the Regenerating and Degenerating CNS supports the assertion that understanding microglial biology could perhaps be pivotal for unraveling the pathogenetic mechanisms that underlie Alzheimer's disease, currently the most ... Read more

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  • Annual, Lunar, and Tidal Clocks

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    Edited by Hideharu Numata, Barbara Helm ...
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    There is more to biological rhythms than circadian clocks. This book aims at promoting the exciting potential of a deeper understanding of circannual, circatidal, and circalunar clocks. It highlights new developments, summarizes existing knowledge, and integrates different perspectives with the tools and ideas of diverse fields of current biology.For predominantly pragmatic reasons, research in ... Read more

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  • Folding for the Synapse

    Folding for the Synapse addresses the current view on how protein folding and misfolding, controlled by molecular chaperones, contribute to synapse function and dysfunction. Molecular chaperones have been studied in relation to de novo protein folding, but there is increasing awareness that chaperone function is required for the regulation of protein dynamics when functioning physiologically as an ... Read more

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  • Myelinated Fibers and Saltatory Conduction in the Shrimp

    The Fastest Impulse Conduction in the Animal Kingdom

    Series series Biomedical and Life Sciences (R0)
    In 1961, neurobiologists found that the conduction velocity of the nerve impulse in the giant nerve fiber of the Penaeus shrimp abdominal nerve cord was over 200 m/s, the highest speed of information transmission ever observed in the animal kingdom. The peculiar myelin sheath with its unique nodal structure and the electrical properties of the nerve fibers of the shrimp have continued to be ... Read more

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  • Development of the Rat Spinal Cord: Immuno- and Enzyme Histochemical Approaches

    Series Book 129 - Advances in Anatomy, Embryology and Cell Biology
    The studies described here were carried out in the Neuroregul ation Group, Department of Physiology, University of Leiden, the Netherlands. Over the last decade, this group, in close collaboration with the Department of Neurosurgery of the Academic Hospital of Leiden, has studied the development of the central nervous system from a neuroanatomical as well as a clinical perspective. During this ... Read more

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