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Top Series in United States

Showing 1 - 12 of 12 results for “thomas decker”
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  • Jak-Stat Signaling : From Basics to Disease

    Edited by Thomas Decker, Mathias Müller ...
    Series series Biomedical and Life Sciences (R0)
    JAK tyrosine kinases and STAT transcription factors constitute a signaling pathway, which is activated by cytokines. By activating gene transcription it regulates essential biological responses to environmental cues. The Jak-Stat pathway is involved in the regulation of cell development, differentiation, proliferation and apoptosis. Improper function may contribute to hematopoietic malignancies ... Read more

    $143.09 USD

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  • Lentiviral Vectors and Gene Therapy

    by David Escors, Karine Breckpot, Frederick Arce, Grazyna Kochan, Holly Stephenson ...
    Series series Biomedical and Life Sciences (R0)
    Gene therapy was conceived during the early and mid part of the 20th century. At first, it was considered a revolutionary biomedical procedure, which could potentially cure any disease for which the molecular bases were understood. Since then, gene therapy has gone through many stages and has evolved from a nearly unrealistic perspective to a real life application. Clinical efficacy in humans was ... Read more

    $49.49 USD

  • Introduction to Molecular Medicine

    by Dennis W. Ross ...
    How will increased understanding of the human genome affect our ability to diagnose and treat disease? The subject of recombinant DNA technology is no longer limited to the research laboratory; it is being discussed in ever-widening medical circles. Introduction to Molecular Medicine is especially written for the physician who is not a genetics expert but wishes to understand this new science and ... Read more

    $80.09 USD

  • Decoding the Antibody Repertoire

    High Throughput Sequencing of Multiple Transcripts from Single B Cells

    by Brandon DeKosky ...
    Series series Biomedical and Life Sciences (R0)
    This thesis outlines the development of the very first technology for high-throughput analysis of paired heavy and light-chain antibody sequences, opening an entirely new window for antibody discovery and the investigation of adaptive immune responses to vaccines and diseases.Previous methods for high-throughput immune repertoire sequencing have been unable to provide information on the identity ... Read more

    $89.09 USD

  • Hematopoietic Stem Cell Biology

    Edited by Motonari Kondo ...
    Series series Biomedical and Life Sciences (R0)
    In the summer of 1988, my developmental biology professor announced to the class that hematopoietic stem cells (HSCs) had finally been purified. Somehow, I never forgot the professor’s words. When I started working in Dr. Irv Weissman’s labo- tory at Stanford as a postdoctoral fellow, I realized that the findings mentioned by the professor were from Weissman’s laboratory and had been published in ... Read more

    $98.09 USD

  • Umbilical Cord Blood Banking and Transplantation

    Edited by Karen Ballen ...
    Series series Biomedical and Life Sciences (R0)
    This comprehensive volume discusses the current scope of umbilical cord blood transplantation (UCBT), including recent controversies and future developments for improving clinical outcomes. Its twenty chapters introduce new applications in regenerative medicine and discuss the latest scientific, regulatory, clinical and investigational aspects of cord blood banking. Physicians from around the ... Read more

    $143.09 USD

  • DNA Methylation and Complex Human Disease

    by Michel Neidhart ...
    Series series Translational Epigenetics
    DNA Methylation and Complex Human Disease reviews the possibilities of methyl-group-based epigenetic biomarkers of major diseases, tailored epigenetic therapies, and the future uses of high-throughput methylome technologies. This volume includes many pertinent advances in disease-bearing research, including obesity, type II diabetes, schizophrenia, and autoimmunity. DNA methylation is also ... Read more

    $112.49 USD

  • Regulation of Cytokine Gene Expression in Immunity and Diseases

    Edited by Xiaojing Ma ...
    Series series Biomedical and Life Sciences (R0)
    This book explores the major cytokines, such as IL-1 and IFN-γ, with respect to the regulation of their gene expression and protein production in specific immune cell types. It discusses both healthy physiological settings and in pathological situations in which the expression of some cytokines could be dysregulated, resulting in either immunodeficiency or exacerbated inflammatory sequelae in ... Read more

    $143.09 USD

  • Albinism in Africa

    Historical, Geographic, Medical, Genetic, and Psychosocial Aspects

    Edited by Jennifer Kromberg, Prashiela Manga ...
    Albinism in Africa: Historical, Geographic, Medical, Genetic, and Psychosocial Aspects provides the first in-depth reference for understanding and treating patients of human albinism in Africa. Leading international contributors examine the historical, geographic, psychosocial, genetic and molecular considerations of importance in effectively and sensitively managing this genetic disorder. ... Read more

    $112.49 USD

  • Molecular and Cellular Biology of Platelet Formation

    Implications in Health and Disease

    Edited by Harald Schulze, Joseph Italiano ...
    This book gives a comprehensive insight into platelet biogenesis, platelet signal transduction, involvement of platelets in disease, the use of diverse animal models for platelet research and future perspectives in regard to platelet production and gene therapy. Being written by international experts, the book is a concise state-of-the art work in the field of platelet biogenesis, biology and ... Read more

    $206.99 USD

  • Human Mast Cells

    by Ann M. Dvorak ...
    Series series Medicine (R0)

    $89.09 USD

  • Stem Cells in Modeling Human Genetic Diseases

    Edited by Mayana Zatz, Oswaldo Keith Okamoto ...
    Series series Biomedical and Life Sciences (R0)
    While most stem cell books focus on basic aspects and/or cell therapy, this book emphasizes the relevance of stem cells obtained from patients, the so-called “patients in a petri dish” as tools to investigate human genetic diseases for which there are no available effective treatment. Chapters embrace several examples of the use of iPS cell technology, a recent Nobel Prize-winning scientific ... Read more

    $89.09 USD