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  • Signaling-Mediated Control of Cell Division

    From Oogenesis to Oocyte-to-Embryo Development

    Edited by Swathi Arur ...
    Series series Biomedical and Life Sciences (R0)
    This volume covers the current knowledge base on the role of signaling and environmental pathways that control the normal development of germline stem cells, meiotic progression of oocytes, events of oocyte maturation and fertilization, and the birth of an embryo.Germ cells are uniquely poised to sustain life across generations through the fusion of oocyte and sperm. Because of the central ... Read more

    $143.99 USD

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  • Is this Cell a Human Being?

    Exploring the Status of Embryos, Stem Cells and Human-Animal Hybrids

    Series series Biomedical and Life Sciences (R0)
    The central question of this book is whether or not particular cell entities of human origin ought to be considered human beings. The answer is crucial for making moral decisions for or against research and experimentation. Experts in the field discuss the production of embryonic-like pluripotent stem cells by altered nuclear transfer, parthenogenesis and reprogramming of adult somatic cells. They ... Read more

    $89.99 USD

  • Lentiviral Vectors and Gene Therapy

    Series series Biomedical and Life Sciences (R0)
    Gene therapy was conceived during the early and mid part of the 20th century. At first, it was considered a revolutionary biomedical procedure, which could potentially cure any disease for which the molecular bases were understood. Since then, gene therapy has gone through many stages and has evolved from a nearly unrealistic perspective to a real life application. Clinical efficacy in humans was ... Read more

    $49.99 USD

  • Molecular Mechanisms of Cell Differentiation in Gonad Development

    Edited by Rafal P. Piprek ...
    Series series Biomedical and Life Sciences (R0)
    This book presents the current state of knowledge on the origin and differentiation of cell lines involved in the development of the vertebrate male and female gonads with particular emphasis on the mouse. It also discusses the processes leading to the testis- and ovary-specific structures and functions.The individual chapters review the origin and differentiation of the somatic cells of the ... Read more

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  • Mouse Development

    From Oocyte to Stem Cells

    Edited by Jacek Z. Kubiak ...
    Series series Biomedical and Life Sciences (R0)
    The mouse is a perfect model organism to study mammalian, and thus indirectly also human, embryology. Most scientific achievements that have had an important impact on the understanding of basic mechanisms governing embryo development in humans, originated from mouse embryology. Stem cell research, which now offers the promise of regenerative medicine, began with the isolation and culture of mouse ... Read more

    $143.09 USD

  • Epigenetics: Development and Disease

    Edited by Tapas Kumar Kundu ...
    Series series Biomedical and Life Sciences (R0)
    Epigenetics is the phenomenon which fine tunes the processes associated with life, beyond that which is specified by the sequence of the genetic material; DNA. The covalent modification of DNA, DNA associated histones, several non histone proteins as well as non coding RNA coherently operate to establish the epigenetic regulation of gene expression in physiological and pathophysiological ... Read more

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  • Limits of Patentability

    Plant Sciences, Stem Cells and Nucleic Acids

    Series series Biomedical and Life Sciences (R0)
    SpringerBriefs in Biotech Patents presents timely reports on intellectual properties (IP) issues and patent aspects in the field of biotechnology. In this volume the limits of patentability are addressed, a question that is often raised when it comes to biotechnological inventions: The first section addresses current issues in the patentability of plants produced by essentially biological ... Read more

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  • Advanced Textbook On Gene Transfer, Gene Therapy And Genetic Pharmacology: Principles, Delivery And Pharmacological And Biomedical Applications Of Nucleotide-based Therapies

    Series Book 1 - Icp Textbooks In Biomolecular Sciences
    This unique advanced textbook provides a clear and comprehensive description of the field of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, along with safety considerations.The use of gene transfer is exponentially growing in the scientific and medical communities for day-to-day cell biology ... Read more

    $62.99 USD

  • Decoding the Antibody Repertoire

    High Throughput Sequencing of Multiple Transcripts from Single B Cells

    Series series Biomedical and Life Sciences (R0)
    This thesis outlines the development of the very first technology for high-throughput analysis of paired heavy and light-chain antibody sequences, opening an entirely new window for antibody discovery and the investigation of adaptive immune responses to vaccines and diseases.Previous methods for high-throughput immune repertoire sequencing have been unable to provide information on the identity ... Read more

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  • DNA Methylation and Complex Human Disease

    Series series Translational Epigenetics
    DNA Methylation and Complex Human Disease reviews the possibilities of methyl-group-based epigenetic biomarkers of major diseases, tailored epigenetic therapies, and the future uses of high-throughput methylome technologies. This volume includes many pertinent advances in disease-bearing research, including obesity, type II diabetes, schizophrenia, and autoimmunity. DNA methylation is also ... Read more

    $112.99 USD

  • Cilia

    Development and Disease

    Edited by Paraskevi Goggolidou ...
    The scope of the book is to highlight the diverse roles of cilia in human development and disease. Almost all cell types form cilia and although they were first detected about 200 years ago, their significance was unclear. In the past ten years, it has become obvious that cilia have got sensory functions, as well as roles in motility and their mis-formation or the deregulation of the signaling ... Read more

    $70.99 USD

  • Asymmetric Cell Division in Development, Differentiation and Cancer

    Series series Biomedical and Life Sciences (R0)
    This book provides readers with an overview of the frequent occurrence of asymmetric cell division. Employing a broad range of examples, it highlights how this mode of cell division constitutes the basis of multicellular organism development and how its misregulation can lead to cancer.To underline such developmental correlations, readers will for example gain insights into stem cell fate and ... Read more

    $170.99 USD