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  • Unlocking Sirtuins

    Cellular Biology to Translational Research

    Unlocking Sirtuins: Cellular Biology to Translational Research explores the intricate roles of sirtuins, from basic principles to clinical significance. The book is organized into six parts, covering foundational concepts, roles in aging and metabolism, disease pathology, therapeutic strategies, future research directions, and potential challenges. Topics include the structure and evolution of ... Read more

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  • Mitochondria and Cancer

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    Mitochondria and Cancer: From Basic Science to Clinical Applications—Understanding Pathogenesis, Therapy Resistance, and Disease Relapse offers comprehensive perspectives about the role of mitochondria in cancer biology and treatment. This book integrates fundamental scientific knowledge with clinical relevance, presenting recent findings that will engage oncology researchers and provide valuable ... Read more

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  • Reactive Oxygen Species in Metabolic Inflammation

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    Series series Biomedical and Life Sciences (R0)
    Reactive oxygen species (ROS)-mediated inflammation plays a critical role in the onset and progression of various metabolic disorders, including obesity, diabetes, and non-alcoholic fatty liver disease (NAFLD). Dysregulated ROS production leads to oxidative stress, which triggers chronic low-grade inflammation, disrupting cellular homeostasis and metabolic functions. This pathological interplay ... Read more

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  • Extrachromosomal DNA in Cancer

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    This book provides a comprehensive review of the emerging role of extrachromosomal DNA (ecDNA) in cancer, highlighting its significance in tumor progression, oncogene amplification, drug resistance, and clinical applications. Extrachromosomal DNA in Cancer: Mechanisms, Biomarkers, and Therapeutic Implications explores the structural and functional characteristics of ecDNA, emphasizing its role in ... Read more

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  • Cancer Metabolism

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    Series series Medicine (R0)
    Cancer cells survive and thrive by radically reshaping the way they use energy, nutrients, and metabolic pathways. This book offers a clear and comprehensive exploration of this rapidly evolving field, revealing how tumors rewire core biochemical processes to sustain proliferation, evade cell death, and adapt to the pressures of the tumor microenvironment. From foundational concepts to cutting ... Read more

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  • Role of Gut Microbiota and Postbiotics for Colorectal Cancer

    Advancing Therapeutic Strategies

    Series series Biomedical and Life Sciences (R0)
    The emerging role of gut microbiota and postbiotics has implications for the management of not only human health and diseases, but also colorectal cancer in particular, as these elements influence colorectal cancer pathogenesis, treatment, and prevention. This book bridges the gap between cutting-edge research and practical clinical applications in the management of colorectal cancer by offering a ... Read more

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  • Biotics and the Gut–Brain Axis in Neurological Disorders

    This book reviews the pivotal role of prebiotics, probiotics, and postbiotics in modulating the gut–brain axis, offering insights into their potential therapeutic applications and impact on neurological health. The initial chapters provide a foundational overview of prebiotics and introduce readers to the concept of the gut–brain axis. These chapters discuss bidirectional communication within the ... Read more

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  • Pharmaceutical Regulatory Affairs

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    This book provides concepts, procedures, guidelines, and regulatory affairs in drug development. Pharmaceutical Regulatory Affairs: Principles and Practices begins with a detailed overview of the drug development life cycle, from initial discovery and preclinical research to clinical trials and market approval, addressing scientific, regulatory, and ethical considerations at each stage. The book ... Read more

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  • Stem Cell Therapeutics

    Discover the revolutionary potential of stem cell therapy and gain a comprehensive understanding of its applications, challenges, and ethical considerations across various medical fields with Stem Cell Therapeutics, a must-read for anyone interested in the future of medicine.Stem Cell Therapeutics delves into the forefront of medical research, exploring the revolutionary potential of stem cell ... Read more

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  • Gastrointestinal Inflammations and Gut Microbiota

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    This book offers a wide perspective on the fundamental and state-of-the-art knowledge in radiobiology, radiation oncology, and the connection between both fields. Chapters incorporate basic concepts of cancer biology and radiobiology with advances in radiotherapy in cancer treatment for various types of cancer. Chapters review one or more areas of radiation oncology with topics ranging from the ... Read more

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  • Postbiotics in Metabolic Disorders

    This book discusses the role of postbiotics in human health. The initial chapter highlights the potential of postbiotics beyond traditional prebiotics and probiotics. Subsequent chapters present the beneficial effects on various health conditions, including cardiovascular disorders, cancer, diabetes, gestational diabetes, obesity, and mitochondrial disorders.The book covers the role of postbiotics ... Read more

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