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  • Human Immunodeficiency Virus Reverse Transcriptase

    Series series Biomedical and Life Sciences (R0)
    The Reverse Transcriptase (RT) of Human Immunodeficiency Virus Type 1 (HIV-1) arguably ranks amongst one of the most extensively studied retroviral enzymes. Heterologous expression and purification of HIV-1 RT in the early eighties, approval of the first nucleoside analogue RT inhibitor (NRTI) in 1987, discovery of resistance to RT inhibitors, approval of the first non-nucleoside analogue RT ... Read more

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    Edited by Ben Adler ...
    Series series Biomedical and Life Sciences (R0)
    This volume covers all aspects of infection by pathogenic Leptospira species, the causative agents of the world’s most widespread zoonosis. Topics include aspects of human and animal leptospirosis as well as detailed analyses of our current knowledge of leptospiral structure and physiology, epidemiology, pathogenesis, genomics, immunity and vaccines. Updates are presented on leptospiral ... Read more

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  • Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics

    Series series Medicine (R0)
    Over the past decade, significant progress has been made in the theory and applications of pharmacodynamics of antimicrobial agents. On the basis of pharmacokinetic-pharmacodynamic modeling concepts it has become possible to describe and predict the time course of antimicrobial effects under normal and pathophysiological conditions. The study of pharmacokinetic-pharmacodynamic relationships can be ... Read more

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  • Crossroads Between Innate and Adaptive Immunity IV

    Series series Biomedical and Life Sciences (R0)
    This volume presents a collection of reviews derived from work presented at the Aegean Conference: “4th Crossroads between innate and adaptive immunity”. This meeting was the fourth in a series, and assembled a team of scientists working on mechanisms by which the innate immune system of the host senses pathogens, the cellular and signaling networks that orchestrate the innate response and antigen ... Read more

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  • Pathology and Pathogenesis of Human Viral Disease

    Pathology and Pathogenesis of Human Viral Disease is a comprehensive reference that examines virus-induced clinical disease of humans in the context of the responsible virus and its epidemiology. Encompassing everything from cold and flu viruses to sexually transmitted diseases, this important resource describes the cellular and tissue pathological changes attributable to infection in the context ... Read more

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  • Hot Topics in Infection and Immunity in Children V

    Series series Biomedical and Life Sciences (R0)
    Course covers topics in infectious diseases in children and is intended for Pediatric Infectious disease trainees, trainers, and all those who manage children with infections.This conference is being supported by several societies and is sponsored by several pharmaceutical companies, such as Aventis, Baxter, Chiron Vaccines, Wyeth, etc. ... Read more

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  • Modern Vaccinology

    Edited by Edouard Kurstak ...
    The recent developments in modern vaccinology are mainly based on: (i) cloning of microbial genes into recombinant vectors containing genetic information for expression of desired neutralizing immunogens; (ii) alternatives of attenuated vectors with deleted genes permitting the insertion of several foreign genes expressing antigens exposed to the host immune system during the abortive replication ... Read more

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  • Reemergence of Established Pathogens in the 21st Century

    Edited by Karl Drlica, I.W. Fong ...
    Series series Medicine (R0)
    In the closing decade of the last century, we saw warnings that infectious diseases will require much more attention from patients and physicians in the 21 st century. Recently d- covered diseases such as AIDS pose a major threat to the population at large, and to that threat has been added the re-emergence of established pathogens, microbes that were re- ily treatable in the past. Since ... Read more

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  • Molecular Mechanisms in Legionella Pathogenesis

    Edited by Hubert Hilbi ...
    Series series Biomedical and Life Sciences (R0)
    Legionnaires’ disease, a potentially fatal type of pneumonia primarily affecting elderly and immuno-compromised persons, is caused by the ubiquitous environmental bacterium Legionella pneumophila. This book offers authoritative reviews of different facets of its virulence, focusing on comparative phagocyte infection, virulence gene regulation, biochemical functions of effector proteins and ... Read more

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  • Vaccines: A Biography

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    Why another book about vaccines? There are already a few extremely well-written medical textbooks that provide comprehensive, state-of-the-art technical reviews regarding vaccine science. Additionally, in the past decade alone, a number of engrossing, provocative books have been published on various related issues ra- ing from vaccines against specific diseases to vaccine safety and policy. Yet ... Read more

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  • Clinical Use of Anti-infective Agents

    A Guide on How to Prescribe Drugs Used to Treat Infections

    Series series Biomedical and Life Sciences (R0)
    This book was designed as a reference tool for pharmacists involved in the treatment of patients with infections. It is clinically oriented and designed to help students in all medical disciplines, and especially pharmacists and students of pharmacy who need information on choosing the correct drug, dose, and method of administration of an agent to patients with infectious diseases. Nurse ... Read more

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  • Antibiotics – Are They Curing Us or Killing Us?

    The Catastrophic Impact of the Over-prescription of Antibiotics on Our Health

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    Antibiotics: Are they curing us or killing us? 'Without urgent, co-ordinated action by many stakeholders, the world is headed for a post-antibiotic era, in which common infections and minor injuries which have been treatable for decades can once again kill.' Dr Keiji Fukuda, World Health Organization For anyone reeling from this recent, shocking statement from WHO, Dr John McKenna is here to help. ... Read more

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