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  • p53 Suppressor Gene

    Series series Molecular Biology Intelligence Unit
    This book is about the p53 gene, one of the most frequently mutated or deleted genes in human cancers. The frequent occurrence of inactivated p53 implicates this gene product in the genesis of many human cancers. The p53 gene can suppress the growth of cancer cells and the transformation process by oncogenes. The p53 protein is a transcription factor that can repress or activate promoters ... Read more

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  • Phosphoinositides I: Enzymes of Synthesis and Degradation

    Series series Biomedical and Life Sciences (R0)
    Phosphoinositides play a major role in cellular signaling and membrane organization. During the last three decades we have learned that enzymes turning over phosphoinositides control vital physiological processes and are involved in the initiation and progression of cancer, inflammation, neurodegenerative, cardiovascular, metabolic disease and more. In two volumes, this book elucidates the crucial ... Read more

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  • Oocyte Biology in Fertility Preservation

    Edited by S. Samuel Kim ...
    Series series Biomedical and Life Sciences (R0)
    Fertility preservation has become one of the most important and fast growing fields of reproductive medicine. Although there are several strategies for fertility preservation in female, most of them are still considered experimental. It is important to perfect the existing technologies, but also developing new strategies should be actively sought. The future development of fertility preservation ... Read more

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  • Fundamentals of Protein Structure and Function

    Series series Biomedical and Life Sciences (R0)
    This book serves as an introduction to protein structure and function. Starting with their makeup from simple building blocks, called amino acids, the 3-dimensional structure of proteins is explained. This leads to a discussion how misfolding of proteins causes diseases like cancer, various encephalopathies, or diabetes. Enzymology and modern concepts of enzyme kinetics are then introduced, taking ... Read more

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  • The Big Book on Small Heat Shock Proteins

    Series Book 8 - Heat Shock Proteins
    Based upon a workshop entitled “The Small HSP World” held in Québec 2-5 October 2014. Twenty-five scientists provided chapters for the book. The chapters are from the best scientists currently working in this field. These colleagues include Arrigo, Benesch, Benjamin, Buchner-Haslbeck-Weinkauf, Benndorf, Boelens, Carra, Chang, Currie, Ecroyd, Emanuelsson, Fu, Garrido, Golenhofen, Gusev, Hightower, ... Read more

    $170.09 USD

  • Computational and Statistical Epigenomics

    Edited by Andrew E. Teschendorff ...
    Series series Biomedical and Life Sciences (R0)
    This book introduces the reader to modern computational and statistical tools for translational epigenomics research. Over the last decade, epigenomics has emerged as a key area of molecular biology, epidemiology and genome medicine. Epigenomics not only offers us a deeper understanding of fundamental cellular biology, but also provides us with the basis for an improved understanding and ... Read more

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  • Surface Active Monomers

    Synthesis, Properties, and Application

    Series series Chemistry and Material Science (R0)
    This brief includes information on the background of and development of synthesis of various types of surface active monomers. The authors explain the importance of utilization of surface active monomers for creation of surface active polymers and the various biomedical applications of such compounds . This brief introduces techniques for the synthesis of novel types of surface active monomers, ... Read more

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  • Molecular Targets and Strategies in Cancer Prevention

    Edited by Malay Chatterjee ...
    The book focuses on the understanding of molecular pathways by which normal cell progress to the definable stage of cancer. The chapters explore microbiota and chronic inflammation, multiple myeloma chemoprevention, microRNAs, cancer regulation, liquid biopsies, and angiogenesis. Recent advances of molecular risk assessment, tumor microenvironment, microneoplasia, malignant gene expressions are ... Read more

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  • Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy

    New Perspectives and Opportunities

    Edited by Christopher D. Gregory ...
    Series series Biomedical and Life Sciences (R0)
    This book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment. Its nine chapters discuss modulation of anti-tumor inflammatory and immune responses, effects on the tumor microenvironment, to strategies for improving pro-apoptotic therapies, mechanisms and implications for disease pathogenesis, axl and mer receptor tyrosine kinases, immunogenic ... Read more

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  • Principles of Molecular Oncology

    Series series Medicine (R0)
    Drawing on years of significant scientific advances and clinical developments, the editors of POMO III have thoroughly updated the highly praised first and second editions and added new chapters to reflect the knowledge emerging from research on genomics, proteomics, chemoprevention strategies, new molecular targets, therapeutic monoclonal antibodies, and innovative cytotoxic and cytostatic small ... Read more

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  • Tactics in Contemporary Drug Design

    Edited by Nicholas A. Meanwell ...
    Series series Chemistry and Material Science (R0)
    Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. ... Read more

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  • MHC Class I Antigens In Malignant Cells

    Immune Escape And Response To Immunotherapy

    Series series Biomedical and Life Sciences (R0)
    Abnormal expression of MHC class I molecules in malignant cells is a frequent occurrence that ranges from total loss of all class I antigens to partial loss of MHC specific haplotypes or alleles. Different mechanisms are described to be responsible for these alterations, requiring different therapeutic approaches. A complete characterization of these molecular defects is important for improvement ... Read more

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