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  • Induced Pluripotent Stem Cells in Brain Diseases

    Understanding the Methods, Epigenetic Basis, and Applications for Regenerative Medicine.

    Series series Biomedical and Life Sciences (R0)
    Brain diseases can have a large impact on patients and society, and treatment is often not available. A new approach in which somatic cells are reprogrammed into induced pluripotent cells (iPS cells) is a significant breakthrough for regenerative medicine. This promises patient-specific tissue for replacement therapies, as well as disease-specific cells for developmental modeling and drug ... Read more

    $49.49 USD

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  • Trinucleotide Diseases and Instability

    Edited by Ben A. Oostra ...
    Series series Biomedical and Life Sciences (R0)
    Till recently, mutations in genes were described in textbooks as deletions or point mutations. These mutations can be inherited from a parent or they are de novo alterations. The discovery in 1991 that human disease can be caused by large-scale ex pansion of highly unstable trinucleotide repeats has elucidated a new mutation mechanism, heritable unstable DNA. In the subsequent years more then 10 ... Read more

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  • Stem Cell Biology in Neoplasms of the Central Nervous System

    Edited by Moneeb Ehtesham ...
    Series series Biomedical and Life Sciences (R0)
    This volume presents the most current reviews on how cancer stem cells (CSCs) hypothesis dictates that the continued proliferation of a tumor is dependent on a sub-population of self-renewing and asymmetrically dividing neoplastic stem cells that supply a largely differentiated tumor. This volume provides a comprehensive overview of the characteristics of CSCs, their role in central nervous system ... Read more

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  • The Custom-Made Brain

    Cerebral Plasticity, Regeneration, and Enhancement

    Two leading neuroscientists examine how the brain is in flux and how this applies to addressing neurological, cognitive, and emotional health.Beginning with a survey of the fundamental scientific developments that led to our current understanding of the regenerative mind, the authors elucidate the breakthrough neurobiological studies that paved the way for our present understanding of the brain's ... Read more

    $12.99 USD or Free with Kobo Plus

  • Bone marrow stem cell therapy for stroke

    This book covers recent advances in all aspects of bone marrow-derived stem cells (BMSCs) for stroke treatment, while also providing comprehensive information on human clinical trials and animal models of stroke. In addition, it reviews the optimal conditions of transplantation for stroke therapy and potential mechanisms underlying transplanted cell-mediated functional recovery after stroke. As ... Read more

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  • From Molecules to Networks

    An Introduction to Cellular and Molecular Neuroscience

    An understanding of the nervous system at virtually any level of analysis requires an understanding of its basic building block, the neuron. From Molecules to Networks provides the solid foundation of the morphologic, biochemical, and biophysical properties of nerve cells. All chapters have been thoroughly revised for this second edition to reflect the significant advances of the past 5 years. The ... Read more

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  • Perspectives of Stem Cells

    From tools for studying mechanisms of neuronal differentiation towards therapy

    Edited by Henning Ulrich ...
    Series series Biomedical and Life Sciences (R0)
    Stem cells are fascinating cell types. They can replicate themselves forever while retaining the potential to generate progeny with speci?c functions. Because of these special properties, stem cells have been subjects of intensive investigation, from understanding basic mechanisms underlying tissue generation, to modeling human diseases, to application for cell replacement therapy. Stem cells come ... Read more

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  • Cell Therapy for Brain Injury

    Edited by David C. Hess ...
    Series series Biomedical and Life Sciences (R0)
    Cell Therapy for Brain Injury is a thorough examination of using state-of-the-art cell therapy in the treatment of strokes and other traumatic brain injuries. This invaluable book covers this niche topic in depth from basic stem cell biology and principles of cell therapy through proposed mechanisms of action of cell therapy in stroke, pre-clinical data in stroke models, ongoing clinical trials, ... Read more

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  • Stem Cells and Cancer Stem Cells, Volume 4

    Therapeutic Applications in Disease and Injury

    Edited by M.A. Hayat ...
    Series series Biomedical and Life Sciences (R0)
    Vast therapeutic applications of the following specific stem cells in disease and tissue injury are discussed: embryonic stem cells, induced pluripotent stem cells, human hair follicle stem cells, bone marrow-derived human mesenchymal stem cells, adipose-derived stem cells, periodontal/progenitor cells, cancer stem cells, and breast cancer stem cells. Because human embryonic stem cells possess the ... Read more

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  • Programmed Cells from Basic Neuroscience to Therapy

    Edited by Fred H. Gage, Yves Christen ...
    Series series Biomedical and Life Sciences (R0)
    The recent advances in Programming Somatic Cell (PSC) including induced Pluripotent Stem Cells (iPS) and Induced Neuronal phenotypes (iN), has changed our experimental landscape and opened new possibilities. The advances in PSC have provided an important tool for the study of human neuronal function as well as neurodegenerative and neurodevelopmental diseases in live human neurons in a controlled ... Read more

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  • Neural Stem Cells in Development, Adulthood and Disease

    Series series Biomedical and Life Sciences (R0)
    This comprehensive volume is the first to specifically target developing, adult and diseased neural stem cells. It explores recent advances in the understanding of neural stem cell biology along with strategies that use these cells to tackle neurological diseases and brain aging. Ten inclusive chapters discuss a wide range of topics including neurogenesis, neurodegeneration, demyelinating disease, ... Read more

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  • Endogenous Stem Cell-Based Brain Remodeling in Mammals

    Series series Stem Cell Biology and Regenerative Medicine
    This text highlights the endogenous regenerative potential of the central nervous system in neonates and juveniles and discusses possible ways it might be manipulated for medical purposes. The first section provides a descriptive summary of the salient steps of human brain development with a discussion of comparisons with other mammalian brains. It also provides a historical perspective on our ... Read more

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