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  • Brown Adipose Tissue

    Series Book 251 - Handbook of Experimental Pharmacology
    The main focus of this book is on brown adipose tissue and its metabolic function. The book provides a timely update on the latest research and shows where the field is heading. Brown adipose tissue (BAT) dissipates energy and has received considerable attention in the last few years, having been re-discovered in adult humans in 2007/9. Moreover, BAT might offer a target for novel therapies to ... Read more

    $188.09 USD

  • Metabolic Control

    Edited by Stephan Herzig ...
    Series Book 233 - Handbook of Experimental Pharmacology
    The HEP issue on Metabolic Control provides a state-of the art overview over both classical concepts and emerging areas in metabolism and associated disorders. In this context, metabolic control is highlighted at various levels of complexity ranging from transcriptional mechanisms in metabolic pathway control over metabolic communication routes in physiology and pathophysiology to current ... Read more

    $188.99 USD

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    Pathophysiology, Pharmacology and Therapeutics: an Update

    Series series Biomedical and Life Sciences (R0)
    This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is ... Read more

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  • Progestins and the Mammary Gland

    From Basic Science to Clinical Applications

    Series series Springer Nature Proceedings excluding Computer Science
    Progestins play a key role in reproductive endocrinology and as pharmaceutical drugs for contraception and in combined hormone therapy. To further our understanding of progestin action in the mammary gland, an international symposium, attended by leading researchers from academia and industry, was held in Berlin, 21–23 March 2007. Genetic mouse models helped to elucidate the role of progestins, ... Read more

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  • New Molecular Mechanisms of Estrogen Action and Their Impact on Future Perspectives in Estrogen Therapy

    Series series Medicine (R0)
    From our current knowledge, it is obvious that estrogen action in volves more than reproduction and fertility. Rather, estrogens affect and influence a number of other organ systems such as the immune, cardiovascular and central nervous system as well as the gastrointes tinal tract, urinary tract and skeleton. The importance of estrogens and estrogen receptor activity is appreciated from the ... Read more

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  • Tissue-Specific Estrogen Action

    Novel Mechanisms, Novel Ligands, Novel Therapies

    Series series Springer Nature Proceedings excluding Computer Science
    Nuclear hormone receptors are not only important drug targets, but have also been the focus of decades of active and highly insightful research. Ten years ago, a review on nuclear receptors was entitled “The Second Decade” and a special issue of Molecular Endocrinology in 2005 dealt with the results of these research efforts. The consensus from nuclear receptor research was of course that the ... Read more

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  • Tryptophan Metabolism: Implications for Biological Processes, Health and Disease

    Series series Molecular and Integrative Toxicology
    This book discusses the relationship between cellular immunity and tryptophan metabolism, as well as its products, serotonin and melatonin, in the development of several diseases and reappraises the common signal transduction pathways of the neurodegenerative diseases, carcinogenesis, immune tolerance, inflammation, hypersensitivity reactions, neuropsychiatric disorders, in addition to bacterial ... Read more

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  • Cell Culture in Pharmaceutical Research

    Edited by N.E. Fusenig, H. Graf ...
    Series series Medicine (R0)
    Cell biology has made an appreciable impact on the evaluation of physiological and pathophysiological processes leading to a more detailed understanding of the signaling mechanisms by which cells communicate in vivo and in vitro and modify adaptively. By using cell culture models in addition to animal experiments we are now able to better define the overall and the selective potential of drugs. ... Read more

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  • Molecular Diagnostics: Promises and Possibilities

    Series series Biomedical and Life Sciences (R0)
    A rapid development in diverse areas of molecular biology and genetic engineering resulted in emergence of variety of tools. These tools are not only applicable to basic researches being carried out world over, but also exploited for precise detection of abnormal conditions in plants, animals and human body. Although a basic researcher is well versed with few techniques used by him/her in the ... Read more

    $170.99 USD

  • Therapeutic Vaccination Strategies

    Edited by P. Walden, W. Sterry, H. Hennekes ...
    Series series Medicine (R0)
    The induction of immune responses against tumor cells by vaccination is rapidly evolving as a therapeutic modality with new potentials for the treatment of cancer. It is based on the fact that our immune system can identify tumor cells and, once activated, is capable of developing specific immunity against the neoplastic cells. Numerous observations and intense research clearly document the major ... Read more

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  • JIMD Reports, Volume 25

    Series series Biomedical and Life Sciences (R0)
    JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder. ... Read more

    $89.09 USD