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Top Series in United States

Showing 1 - 12 of 12 results for “s pahernik”
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  • Innate Immunity: Resistance and Disease-Promoting Principles

    by S. Pahernik ...
    Series series
    Our understanding of the complex innate immune response is increasing rapidly. Its role in the protection against viral or bacterial pathogens is essential for the survival of an organism. However, it is equally important to avoid unregulated inflammation because innate immune responses can cause or promote chronic autoinflammatory diseases such as gout, atherosclerosis, type 2 diabetes or certain ... Read more

    $83.69 USD

  • Advances in Stem Cell Aging

    by S. Pahernik ...
    Series series
    Adult stem cells are present in most postnatal tissues of mammals. Tissues with high rates of cell turnover depend on the functional capacity of stem cells for lifelong maintenance of tissue homeostasis. Adult stem cells are also required for the regeneration of tissues in response to injury as in, for example, the regeneration of skeletal muscle. In addition to its function in tissue homeostasis ... Read more

    $83.69 USD

  • Adult Stem Cells in Aging, Diseases and Cancer

    by S. Pahernik ...
    Series series
    The functionality of adult tissue stem cells from various organ systems declines during aging. This publication summarizes novel molecular mechanisms responsible for the development of aging-associated deficiencies as discussed by leading experts during the 5th Else Kröner-Fresenius Symposium. It is the first book that explicitly focuses on molecular mechanisms of stem cell aging and its ... Read more

    $83.69 USD

  • Molecular Mechanisms of Adult Stem Cell Aging

    by S. Pahernik ...
    Series series Else Kröner-Fresenius Symposia
    There is growing evidence that adult stem cells age. This process can result in alterations in the number and function of stem cells, leading to distinct phenotypic outcomes in different organ systems. This publication provides an outstanding overview of this emerging field. The molecular causes of stem cell aging remain to be defined. Stem cell aging can involve cell-intrinsic as well as cell ... Read more

    $100.79 USD

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  • Cancer Stem Cells

    Edited by William L. Farrar, PhD ...
    A remarkable paradigm shift has occurred in recent years regarding the biological origins of cancer. The cancer stem cell hypothesis challenged the foundational notions of cancer, and the therapeutic implications have been profound. Compelling evidence indicates that errors in the development of a small subset of adult stem cells can lead to cancer. Only this small sub-population of cells has the ... Read more

    $109.09 USD

  • Lentiviral Vectors and Gene Therapy

    by David Escors, Karine Breckpot, Frederick Arce, Grazyna Kochan, Holly Stephenson ...
    Series series Biomedical and Life Sciences (R0)
    Gene therapy was conceived during the early and mid part of the 20th century. At first, it was considered a revolutionary biomedical procedure, which could potentially cure any disease for which the molecular bases were understood. Since then, gene therapy has gone through many stages and has evolved from a nearly unrealistic perspective to a real life application. Clinical efficacy in humans was ... Read more

    $49.49 USD

  • Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants

    Edited by Yvonne Will, James A. Dykens ...
    Developed as a one-stop reference source for drug safety and toxicology professionals, this book explains why mitochondrial failure is a crucial step in drug toxicity and how it can be avoided.• Covers both basic science and applied technology / methods• Allows readers to understand the basis of mitochondrial function, the preclinical assessments used, and what they reveal about drug effects• ... Read more

    $334.00 USD

  • Stem Cells

    From Biology to Therapy, 2 Volumes

    Edited by Robert A. Meyers ...
    Series series Advances in Molecular Biology and Medicine
    This third in the Current Topics in Molecular Cell Biology and Molecular Medicine Series contains a careful selection of new and updated, high-quality articles from the well-known Meyer's Encyclopedia, describing new perspectives in stem cell research. The 26 chapters are divided into four sections: Basic Biology, Stem Cells and Disease, Stem Cell Therapy Approaches, and Laboratory Methods, with ... Read more

    $256.00 USD

  • Analogue-based Drug Discovery II

    Edited by C. Robin Ganellin, János Fischer ...
    Born out of a project of the IUPAC's committee on Medicinal Chemistry and Drug Development, this reference addresses past and current strategies for successful drug analog development, extending the previously published volume by nine new analog classes and eight case studies. Like its precursor, this volume also contains a general section discussing universally applicable strategies for analog ... Read more

    $212.00 USD

  • Cancer Stem Cells

    by Vinagolu K. Rajasekhar ...
    Cancer Stem Cells covers a wide range of topics in cancer stem cell biology, including the functional characteristics of cancer stem cells and how they're generated, where they are localized, the means by which cancer stem cells can be targeted, and how cancer stem cells can be reprogrammed back to normal tissue stem cells. Each chapter begins with a brief historical note and concept summary, ... Read more

    $178.00 USD

  • Medicinal Chemistry Approaches to Personalized Medicine

    by Raimund Mannhold, Hugo Kubinyi, Gerd Folkers ...
    Series Book 59 - Methods & Principles in Medicinal Chemistry
    Edited by two renowned medicinal chemists who have pioneered the development of personalized therapies in their respective fields, this authoritative analysis of what is already possible is the first of its kind, and the only one to focus on drug development issues.Numerous case studies from the first generation of "personalized drugs" are presented, highlighting the challenges and opportunities ... Read more

    $126.00 USD

  • Peptide-based Drug Discovery

    Challenges and New Therapeutics

    Edited by Ved Srivastava ...
    Series Book 59 - Drug Discovery Series
    With potentially high specificity and low toxicity, biologicals offer promising alternatives to small-molecule drugs. Peptide therapeutics have again become the focus of innovative drug development efforts backed up by a resurgence of venture funds and small biotechnology companies.What does it take to develop a peptide-based medicine? What are the key challenges and how are they overcome? What ... Read more

    $225.89 USD