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Showing 1 - 12 of 12 results for “peter f thall”
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  • Bayesian Precision Medicine

    by Peter F. Thall ...
    Series series Chapman & Hall/CRC Biostatistics Series
    Bayesian Precision Medicine presents modern Bayesian statistical models and methods for identifying treatments tailored to individual patients using their prognostic variables and predictive biomarkers. The process of evaluating and comparing treatments is explained and illustrated by practical examples, followed by a discussion of causal analysis and its relationship to statistical inference. A ... Read more

    $77.99 USD

  • Statistical Remedies for Medical Researchers

    by Peter F. Thall ...
    Series series Mathematics and Statistics (R0)
    This book illustrates numerous statistical practices that are commonly used by medical researchers, but which have severe flaws that may not be obvious. For each example, it provides one or more alternative statistical methods that avoid misleading or incorrect inferences being made. The technical level is kept to a minimum to make the book accessible to non-statisticians. At the same time, since ... Read more

    $80.99 USD

  • Bayesian Designs for Phase I-II Clinical Trials

    by Ying Yuan, Hoang Q. Nguyen, Peter F. Thall ...
    Series series Chapman & Hall/CRC Biostatistics Series
    Reliably optimizing a new treatment in humans is a critical first step in clinical evaluation since choosing a suboptimal dose or schedule may lead to failure in later trials. At the same time, if promising preclinical results do not translate into a real treatment advance, it is important to determine this quickly and terminate the clinical evaluation process to avoid wasting resources.Bayesian ... Read more

    $64.99 USD

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  • Applied Statistical Inference

    Likelihood and Bayes

    by Leonhard Held, Daniel Sabanés Bové ...
    Series series Mathematics and Statistics (R0)
    This book covers modern statistical inference based on likelihood with applications in medicine, epidemiology and biology. Two introductory chapters discuss the importance of statistical models in applied quantitative research and the central role of the likelihood function. The rest of the book is divided into three parts. The first describes likelihood-based inference from a frequentist ... Read more

    $62.99 USD

  • Nonclinical Statistics for Pharmaceutical and Biotechnology Industries

    by Max Kuhn, Ian Peers, Stan Altan ...
    Series series Mathematics and Statistics (R0)
    This book serves as a reference text for regulatory, industry and academic statisticians and also a handy manual for entry level Statisticians. Additionally it aims to stimulate academic interest in the field of Nonclinical Statistics and promote this as an important discipline in its own right. This text brings together for the first time in a single volume a comprehensive survey of methods ... Read more

    $170.09 USD

  • Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models

    by Joel S. Owen, Jill Fiedler-Kelly ...
    This book provides a user-friendly, hands-on introduction to the Nonlinear Mixed Effects Modeling (NONMEM) system, the most powerful tool for pharmacokinetic / pharmacodynamic analysis.• Introduces requisite background to using Nonlinear Mixed Effects Modeling (NONMEM), covering data requirements, model building and evaluation, and quality control aspects• Provides examples of nonlinear modeling ... Read more

    $102.00 USD

  • Expect The Unexpected: A First Course In Biostatistics (Second Edition)

    by Raluca Balan, Gilles Lamothe ...
    This textbook introduces the basic concepts from probability theory and statistics which are needed for statistical analysis of data encountered in the biological and health sciences. No previous study is required. Advanced mathematical tools, such as integration and differentiation, are kept to a minimum. The emphasis is put on the examples. Probabilistic methods are discussed at length, but the ... Read more

    $31.49 USD

  • Benefit-Risk Assessment Methods in Medical Product Development

    Bridging Qualitative and Quantitative Assessments

    Edited by Qi Jiang, Weili He ...
    Series series Chapman & Hall/CRC Biostatistics Series
    Guides You on the Development and Implementation of B–R EvaluationsBenefit–Risk Assessment Methods in Medical Product Development: Bridging Qualitative and Quantitative Assessments provides general guidance and case studies to aid practitioners in selecting specific benefit–risk (B–R) frameworks and quantitative methods. Leading experts from industry, regulatory agencies, and academia present ... Read more

    $72.99 USD

  • Practical Considerations for Adaptive Trial Design and Implementation

    Edited by Weili He, Olga M. Kuznetsova, José Pinheiro ...
    Series series Mathematics and Statistics (R0)
    This edited volume is a definitive text on adaptive clinical trial designs from creation and customization to utilization. As this book covers the full spectrum of topics involved in the adaptive designs arena, it will serve as a valuable reference for researchers working in industry, government and academia. The target audience is anyone involved in the planning and execution of clinical trials, ... Read more

    $170.09 USD

  • Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials

    by Toshiro Tango ...
    Series series Chapman & Hall/CRC Biostatistics Series
    Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials is the first book focused on the application of generalized linear mixed models and its related models in the statistical design and analysis of repeated measures from randomized controlled trials. The author introduces a new repeated measures design called S:T design combined with mixed models as a ... Read more

    Was $72.99 USD Now $64.99 USD

  • Quick Guide to Good Clinical Practice

    How to Meet International Quality Standard in Clinical Research

    by Cemal Cingi, Nuray Bayar Muluk ...
    Series series Medicine (R0)
    This brand-new book offers a reference guide to understanding and applying the rules for properly conducting clinical trials to meet the international quality standard – Good Clinical Practice – provided by the International Conference on Harmonization (ICH).The work offers an updated perspective on the clinical research landscape within the context of the clinical trial regulatory frameworks in ... Read more

    $89.09 USD

  • Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials

    Edited by John O'Quigley, Alexia Iasonos, Björn Bornkamp ...
    Series series Chapman & Hall/CRC Handbooks of Modern Statistical Methods
    Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials gives a thorough presentation of state-of-the-art methods for early phase clinical trials. The methodology of clinical trials has advanced greatly over the last 20 years and, arguably, nowhere greater than that of early phase studies. The need to accelerate drug development in a rapidly evolving context of targeted ... Read more

    $110.99 USD