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  • Studies on Arthritis and Joint Disorders

    Series series Biomedical and Life Sciences (R0)
    This next volume in our established series proposes to systematically review the basic science and clinical knowledge of the role of free radicals and antioxidants, collectively known as “oxidative stress”, in the pathology of arthritis and other joint diseases. It will describe the most current diagnostic tools , laboratory methods and technology, to suggest ways of prevention and treatment and ... Read more

    $152.09 USD

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    A Very Short Introduction

    Series series Very Short Introductions
    How does the brain work? How different is a human brain from other creatures' brains? Is the human brain still evolving? In this fascinating book, Michael O'Shea provides a non-technical introduction to the main issues and findings in current brain research, and gives a sense of how neuroscience addresses questions about the relationship between the brain and the mind. Chapters tackle subjects ... Read more

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  • Arachidonate Remodeling and Inflammation

    Series series Progress in Inflammation Research
    Arachidonic acid (AA) and other 20 or 22-carbon polyunsaturated fatty acids (PUFAs) are precursors of lipid mediators of inflammation known as eicosanoids. These mediators are critical in disease processes and in regulating normal cell function. Remodeling is important in maintaining homeostasis and in regulating cell function by dictating how PUFAs are converted to lipid mediators of inflammation ... Read more

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  • RNA Methodologies

    Laboratory Guide for Isolation and Characterization

    This is the fourth edition of the successful laboratory guide which has translated the rich story of riboneucleic acid for over fifteen years. RNA Methodologies 4e presents the latest collection of tested laboratory protocols for the isolation and characterization of eukaryotic and prokaryotic RNA with greater emphasis on transcript profiling, including quantification issues and elucidation of ... Read more

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  • Agammaglobulinemia

    Series series Medicine (R0)
    This book provides an updated overview of agammaglobulinemia, a rare form of primary immunodeficiency which is considered the prototype of the congenital humoral defects, and which is characterized by the absence of peripheral B cells and very low serum immunoglobulin levels. The book opens by discussing the highly orchestrated early B cell development in the bone marrow and the genes involved ... Read more

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  • Bone Morphogenetic Proteins: Regeneration of Bone and Beyond

    Series series Medicine (R0)
    Since the discovery of the bone morphogenetic proteins (BMPs) more than 15 years ago, there has been an unpredicted explosion of both basic scientific discoveries and clinical reports on their use from institutions all over the world. The potent effica cy of BMPs in almost all crucial developmental events as well as during regenera tion of various organs such as bone, kidney, brain, liver, heart ... Read more

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  • Cytokines and Joint Injury

    Series series Progress in Inflammation Research
    The purpose of this volume in the Progress in Inflammation Research series is to provide the biomedical and clinical researcher with a state-of-the-art insight in the role of cytokines in joint inflammation and joint destruction. This is of relevance for better understanding of key processes in diseases such as rheumatoid arthritis (RA) and osteoarthritis (OA). Apart from the impact of old and ... Read more

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  • Hormone Resistance and Other Endocrine Paradoxes

    Edited by Margo P. Cohen, Piero P. Foa ...
    Series series Medicine (R0)
    Endocrinology and Metabolism: Progress in Research and Clinical Prac tice is a new series that has been designed to present timely, critical reviews of constantly evolving fields; to provide practical and up-to-date guidance in the solution of pertinent clinical problems; to offer an alterna tive to the laborious search of the literature (and the often frustrating reading of highly technical ... Read more

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  • Jak-Stat Signaling : From Basics to Disease

    Series series Biomedical and Life Sciences (R0)
    JAK tyrosine kinases and STAT transcription factors constitute a signaling pathway, which is activated by cytokines. By activating gene transcription it regulates essential biological responses to environmental cues. The Jak-Stat pathway is involved in the regulation of cell development, differentiation, proliferation and apoptosis. Improper function may contribute to hematopoietic malignancies ... Read more

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  • Biobanking in the 21st Century

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    Series series Biomedical and Life Sciences (R0)
    Biobanking, an emerging field supported by academia, industry and health administrators alike, is distinctly different today from the practice that once defined it. The science of Biobanking, which initially involved simply storing blood or tissue samples in a freezer, is now a highly sophisticated field of research, and expected to grow exponentially over the next decade or two. This book aims to ... Read more

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  • DNA Replication

    From Old Principles to New Discoveries

    Edited by Hisao Masai, Marco Foiani ...
    Series series Biomedical and Life Sciences (R0)
    This book reviews the latest trends and future directions of DNA replication research. The contents reflect upon the principles that have been established through the genetic and enzymatic studies of bacterial, viral, and cellular replication during the past decades. The book begins with a historical overview of the studies on eukaryotic DNA replication by Professor Thomas Kelly, a pioneer of the ... Read more

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  • Chromatin

    Structure & Function

    The Third Edition of Chromatin: Structure and Function brings the reader up-to-date with the remarkable progress in chromatin research over the past three years. It has been extensively rewritten to cover new material on chromatin remodeling, histone modification, nuclear compartmentalization, DNA methylation, and transcriptional co-activators and co-repressors. The book is written in a clear and ... Read more

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