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  • Airway Mucus: Basic Mechanisms and Clinical Perspectives

    Edited by D.F. Rogers, M.I. Lethem ...
    Series series Respiratory Pharmacology and Pharmacotherapy
    Conceptually unsavoury, airway mucus is vital to homeostasis in the respiratory tract. In contrast, when abnormal, mucus contributes significantly to the pathophysiology of a number of severe bronchial diseases, including asthma, chronic bronchitis and cystic fibrosis. This volume provides wide ranging and in-depth coverage of the scientific and clinical aspects of airway mucus. It commences with ... Read more

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  • Sustainable Innovation

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  • Antimicrobial Therapy Guide®, 19th edition

    The leading clinical reference source on therapeutic antimicrobials, this latest edition contains up-to-date treatment guidelines and algorithms for most infections in an expanded, easy-to-read format. Composed by a team of expert contributing editors, this book is conveniently organized and tabbed for quick reference of drug toxicities, prophylaxis strategies, and dosage options. Now available ... Read more

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  • Platelets in Thrombotic and Non-Thrombotic Disorders

    Pathophysiology, Pharmacology and Therapeutics: an Update

    Series series Biomedical and Life Sciences (R0)
    This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is ... Read more

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  • Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models

    This book provides a user-friendly, hands-on introduction to the Nonlinear Mixed Effects Modeling (NONMEM) system, the most powerful tool for pharmacokinetic / pharmacodynamic analysis.• Introduces requisite background to using Nonlinear Mixed Effects Modeling (NONMEM), covering data requirements, model building and evaluation, and quality control aspects• Provides examples of nonlinear modeling ... Read more

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    Edited by Rathnam Chaguturu ...
    Series series Wiley Series on Technologies for the Pharmaceutical Industry
    Can academia save the pharmaceutical industry?The pharmaceutical industry is at a crossroads. The urgent need for novel therapies cannot stem the skyrocketing costs and plummeting productivity plaguing R&D, and many key products are facing patent expiration. Dr. Rathnam Chaguturu presents a case for collaboration between the pharmaceutical industry and academia that could reverse the industry's ... Read more

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  • Cerebral Ischemia and Dementia

    In contrast to dementia of the Alzheimer type, the subject of dementia subsequent to cerebral ischemia has been discussed rather rarely. Now this book provides a summary of the brain morphology, neurochemistry and clinical aspects of dementia subsequent to cerebral ischemia. The contributions discuss the similarities and differences between the two predominant dementia types. The broad range of ... Read more

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  • Smart Pharmaceutical Nanocarriers

    Drug delivery systems and pharmaceutical nanocarriers that respond to different types of stimuli, such as internal ones, intrinsic for the pathological area (changes in pH, temperature, redox condition, activity of certain enzymes), or external, artificially applied (magnetic field, ultrasound, various irradiations), represent an important and continuously growing area of research. Smart ... Read more

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  • New Strategies in Stroke Intervention

    Ionic Transporters, Pumps, and New Channels

    Edited by Lucio Annunziato ...
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    Ischemic brain damage represents a major source of morbidity and mortality in westernized society and poses a significant financial burden on the health care system. To date, few effective therapies have been realized. Recent evidence, however, suggests that channels, pumps, and ionic exchangers are involved in CNS ischemia and ischemic stroke, but the potential contribution of these channels for ... Read more

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