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  • Influenza Virus Sialidase - A Drug Discovery Target

    Edited by Mark Itzstein ...
    Series series Biomedical and Life Sciences (R0)
    Influenza continues to be an ongoing problem despite the existence of vaccines and drugs. Disease outbreaks can occur relatively quickly as witnessed with the recent emergence of the influenza virus A/H1N1 pandemic. The development of new anti-influenza drugs is thus a major challenge.This volume describes all aspects of the virus structure and function relevant to infection. The focus is on drug ... Read more

    $143.09 USD

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  • Antimicrobial Therapy Guide®, 19th edition

    The leading clinical reference source on therapeutic antimicrobials, this latest edition contains up-to-date treatment guidelines and algorithms for most infections in an expanded, easy-to-read format. Composed by a team of expert contributing editors, this book is conveniently organized and tabbed for quick reference of drug toxicities, prophylaxis strategies, and dosage options. Now available ... Read more

    $14.99 USD

  • Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics

    Series series Medicine (R0)
    Over the past decade, significant progress has been made in the theory and applications of pharmacodynamics of antimicrobial agents. On the basis of pharmacokinetic-pharmacodynamic modeling concepts it has become possible to describe and predict the time course of antimicrobial effects under normal and pathophysiological conditions. The study of pharmacokinetic-pharmacodynamic relationships can be ... Read more

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  • Crossroads Between Innate and Adaptive Immunity IV

    Series series Biomedical and Life Sciences (R0)
    This volume presents a collection of reviews derived from work presented at the Aegean Conference: “4th Crossroads between innate and adaptive immunity”. This meeting was the fourth in a series, and assembled a team of scientists working on mechanisms by which the innate immune system of the host senses pathogens, the cellular and signaling networks that orchestrate the innate response and antigen ... Read more

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  • Novel Strategies in the Design and Production of Vaccines

    Series series Biomedical and Life Sciences (R0)
    Vaccination is one of the most efficient and cost effective methods of promoting human health and has been in clinical use for at least 200 years. Nevertheless, infectious diseases continue to constitute a constant threat to the well being of humanity. Common pathogens, once believed to be under control, acquire increased virulence and resistance to drugs, while exotic microorganisms emerged from ... Read more

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  • Modern Vaccinology

    Edited by Edouard Kurstak ...
    The recent developments in modern vaccinology are mainly based on: (i) cloning of microbial genes into recombinant vectors containing genetic information for expression of desired neutralizing immunogens; (ii) alternatives of attenuated vectors with deleted genes permitting the insertion of several foreign genes expressing antigens exposed to the host immune system during the abortive replication ... Read more

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  • Current Topics in Innate Immunity II

    Series series Biomedical and Life Sciences (R0)
    Mounting evidence in the past decade indicates that innate immunity mediates functions above and beyond first-line defense against infection. It is now appreciated that innate immune mechanisms are critically involved in the development of adaptive immunity and, moreover, the regulation of diverse physiological and homeostatic processes. The latter explains why deregulation of innate immunity may ... Read more

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  • Macrolide Antibiotics

    Edited by W. Schönfeld, H.A. Kirst ...
    Series series Milestones in Drug Therapy
    There are only very few chemical classes of antibiotics in medical use, and these have originated over a span of more than 60 years of research. Almost half a century ago, the first member of the macrolides, erythromycin, was introduced as a treatment option for bacterial infections. Erythromycin is a very complex fermentation product obtained from the soil bacterium Saccharopolyspora ery thraea ... Read more

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  • Endotoxins: Structure, Function and Recognition

    Edited by Peter J. Quinn, Xiaoyuan Wang ...
    Series series Biomedical and Life Sciences (R0)
    Endotoxins are potentially toxic compounds produced by Gram-negative bacteria including some pathogens. Unlike exotoxins, which are secreted in soluble form by live bacteria, endotoxins are comprised of structural components of bacteria. Endotoxins can cause a whole-body inflammatory state, sepsis, leading to low blood pressure, multiple organ dysfunction syndrome and death. This book brings ... Read more

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  • Diabetes and Viruses

    Series series Biomedical and Life Sciences (R0)
    This book will assemble the views of many of the world's experts in the field of viruses and diabetes. It will look critically at some unanswered questions, in the field. Among these, How do viruses destroy or modify the pancreatic islet? Which viruses are involved? What is the role of virus-induced cytokines> Could vaccines prevent virus-induced diabetes? Until recent technological advances, ... Read more

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  • Systemic Vasculitides: Current Status and Perspectives

    Series series Biomedical and Life Sciences (R0)
    In spite of their relatively low prevalence, systemic vasculitides have been the object of intensive basic and clinical investigations over the last few years. As a consequence, important advancements have been achieved: from updated diagnostic and classification criteria and a more rational nomenclature to the recognition of an expanding spectrum of clinical manifestations and potentially ... Read more

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  • Antibiotic Policies

    Controlling Hospital Acquired Infection

    Series series Medicine (R0)
    The first book was on "Theory and Practice" of antibiotic stewardship in its broadest sense -the how to do it and the do's and don’ts. The second, on "Controlling resistance" was very much on the relationships between use and resistance and beginning to home in on the hospital as the main generator of resistance, but mainly looking at it from a disease/clinical perspective. The last 3 chapters on ... Read more

    $143.09 USD