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Showing 1 - 12 of 12 results for “leonid gorb”
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  • Application of Computational Techniques in Pharmacy and Medicine

    Edited by Eugene Muratov, Victor Kuz'min, Leonid Gorb ...
    Series series Chemistry and Material Science (R0)
    The proposed volume provides both fundamental and detailed information about the computational and computational-experimental studies which improve our knowledge of how leaving matter functions, the different properties of drugs (including the calculation and the design of new ones), and the creation of completely new ways of treating numerical diseases. Whenever it is possible, the interplay ... Read more

    $188.09 USD

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  • Supramolecular Chemistry

    From Biological Inspiration to Biomedical Applications

    by Peter J. Cragg ...
    The aim of this book is to return to the biomimicry and medicinal potential that inspired many of the early supramolecular chemists and to set it in the context of current advances in the field.Following an overview of supramolecular chemistry, the first section considers the efforts made to synthesize artificial systems that mimic biological entities. The second section addresses the application ... Read more

    $89.09 USD

  • Advance in Structural Bioinformatics

    Edited by Dongqing Wei, Qin Xu, Tangzhen Zhao, Hao Dai ...
    Series series Biomedical and Life Sciences (R0)
    This text examines in detail mathematical and physical modeling, computational methods and systems for obtaining and analyzing biological structures, using pioneering research cases as examples. As such, it emphasizes programming and problem-solving skills. It provides information on structure bioinformatics at various levels, with individual chapters covering introductory to advanced aspects, ... Read more

    $143.09 USD

  • Validation of Alternative Methods for Toxicity Testing

    Edited by Chantra Eskes, Maurice Whelan ...
    Series series Biomedical and Life Sciences (R0)
    This book provides information on best practices and new thinking regarding the validation of alternative methods for toxicity testing. It covers the validation of experimental and computational methods and integrated approaches to testing and assessment. Validation strategies are discussed for methods employing the latest technologies such as tissue-on-a-chip systems, stem cells and ... Read more

    $170.09 USD

  • Multifaceted Roles of Crystallography in Modern Drug Discovery

    Edited by Giovanna Scapin, Disha Patel, Eddy Arnold ...
    Series series Springer Nature Proceedings excluding Computer Science
    The present work offers a snapshot of the state-of-the-art of crystallographic, analytical, and computational methods used in modern drug design and development. Topics discussed include: drug design against complex systems (membrane proteins, cell surface receptors, epigenetic targets, and ribosomes); modulation of protein-protein interactions; the impact of small molecule structures in drug ... Read more

    $89.09 USD

  • Molecular Science of Fluctuations Toward Biological Functions

    Edited by Mikio Kataoka, Ryuichi Ueoka, Yuko Okamoto, Mazahide Terazima ...
    Series series Chemistry and Material Science (R0)
    In this monograph, the importance of fluctuations for biological reactions is discussed from various points of view. Understanding the biological reactions at the molecular level is one of the major targets in many scientific fields, including not only basic biology but also physics, physical chemistry, and medical science. One of the key factors in the process is “fluctuation”. Thermal energy ... Read more

    $89.09 USD

  • Physics at the Biomolecular Interface

    Fundamentals for Molecular Targeted Therapy

    by Ariel Fernández ...
    Series series Physics and Astronomy (R0)
    This book focuses primarily on the role of interfacial forces in understanding biological phenomena at the molecular scale. By providing a suitable statistical mechanical apparatus to handle the biomolecular interface, the book becomes uniquely positioned to address core problems in molecular biophysics. It highlights the importance of interfacial tension in delineating a solution to the protein ... Read more

    $89.99 USD

  • Ion Channels and Their Inhibitors

    Edited by Satya Prakash Gupta ...
    Series series Chemistry and Material Science (R0)
    Being the crucial components of living cells, ion channels are important targets of therapeutic agents. Historically, it has been challenging to develop drugs on this target class. A major issue with target based ion channel drug development is the identification of effective small chemical leads for medicinal chemistry optimization to the clinical candidate status. Thus enough attention has been ... Read more

    $89.09 USD

  • Modelling of GPCRs

    A Practical Handbook

    by Andrea Strasser, Hans-Joachim Wittmann ...
    Series series Biomedical and Life Sciences (R0)
    G protein coupled receptors (GPCRs) comprise an important protein family, which is involved in signal transduction in the cell. Besides that a large number of drugs, available on market, address GPCRs. For an efficient and improved development of appropriate drugs, molecular modelling of GPCRs is – in order to understand the ligand-receptor interactions and functionality of GPCRs on molecular ... Read more

    $143.99 USD

  • Bioinformatics for High Throughput Sequencing

    Edited by Naiara Rodríguez-Ezpeleta, Michael Hackenberg, Ana M. Aransay ...
    Series series Biomedical and Life Sciences (R0)
    Next generation sequencing is revolutionizing molecular biology. Owing to this new technology it is now possible to carry out a panoply of experiments at an unprecedented low cost and high speed. These go from sequencing whole genomes, transcriptomes and small non-coding RNAs to description of methylated regions, identification protein – DNA interaction sites and detection of structural variation. ... Read more

    $143.09 USD

  • Understanding Depression

    Volume 1. Biomedical and Neurobiological Background

    Edited by Yong-Ku Kim ...
    Series series Medicine (R0)
    This book, in two volumes, focuses on contemporary issues and dilemmas in relation to depression. The aim is to equip readers with an up-to-date understanding of the clinical and neurobiological underpinnings of depression and their relation to clinical manifestations and the development of more effective treatments. This first volume is devoted specifically to biomedical and neurobiological ... Read more

    $170.99 USD

  • Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics

    Edited by Hae Won Kim, A. Gerson Greenburg ...
    Series series Chemistry and Material Science (R0)
    Currently, hemoglobin (Hb)-based oxygen carriers (HBOCs) are leading candidates as red blood cell substitutes. In addition, HBOCs are also potential oxygen therapeutics for treatment of patients with critical ischemic conditions due to atherosclerosis, diabetes and other conditions. This book will provide readers a comprehensive review of topics involved in the HBOC development. It focusses on ... Read more

    $143.09 USD