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jianling wang

Showing 1 - 12 of 12 results for “jianling wang
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  • Predictive ADMET

    Integrated Approaches in Drug Discovery and Development

    This book helps readers integrate in silico, in vitro, and in vivo ADMET (absorption, distribution, metabolism, elimination and toxicity) and PK (pharmacokinetics) data with routine testing applications so that pharmaceutical scientists can diagnose ADMET problems and present appropriate recommendations to move drug discovery programs forward.The book introduces the current clinical practice for ... Read more

    $143.00 USD

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  • Specification of Drug Substances and Products

    Development and Validation of Analytical Methods

    Specification of Drug Substances and Products: Development and Validation of Analytical Methods is a comprehensive and critical analysis of the requirements and approaches to setting specifications for new pharmaceutical products, with an emphasis on phase-appropriate development and validation of analytical methods. This book is intended as more than a review of new regional guidelines, existing ... Read more

    $107.99 USD

  • Peptide and Protein Interaction with Membrane Systems

    Applications to Antimicrobial Therapy and Protein Drug Delivery

    by Sara Bobone ...
    Series series Chemistry and Material Science (R0)
    In her thesis, Sara Bobone outlines spectroscopic studies of antimicrobial peptides (AMPs) which are promising lead compounds for drugs used to fight multidrug resistant bacteria. Bobone shows that AMPs interact with liposomes and she clarifies the structure of pores formed by one of these molecules. These results help us to understand how AMPs are selective for bacterial membranes and how their ... Read more

    $89.09 USD

  • Drug Discovery Toxicology

    From Target Assessment to Translational Biomarkers

    As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process.• Guides researchers as to what drug safety experiments are both practical and useful• Covers a variety of key topics – safety lead optimization, in vitro-in vivo ... Read more

    $181.00 USD

  • High-Throughput Screening Methods in Toxicity Testing

    Edited by Pablo Steinberg ...
    Explores the benefits and limitations of the latest high-throughput screening methodsWith its expert coverage of high-throughput in vitro screening methods for toxicity testing, this book makes it possible for researchers to accelerate and streamline the evaluation and risk assessment of chemicals and drugs for toxicity. Moreover, it enables them to comply with the latest standards set forth by ... Read more

    $152.00 USD

  • Oral Formulation Roadmap from Early Drug Discovery to Development

    Edited by Elizabeth Kwong ...
    Detailing formulation approaches by stage of discovery to early development, this book gives a “playbook” of practical and efficient strategies to formulate drug candidates with the least chance of failing in clinical development.• Comes from contributing authors with experience developing formulations on the frontlines of the pharmaceutical industry• Focuses on pre (or non-) clinical and early ... Read more

    $138.00 USD

  • Oral Bioavailability Assessment

    Basics and Strategies for Drug Discovery and Development

    Series series Wiley Series on Pharmaceutical Science and Biotechnology: Practices, Applications and Methods
    Specifically geared to personnel in the pharmaceutical and biotechnology industries, this book describes the basics and challenges of oral bioavailability – one of the most significant hurdles in drug discovery and development.• Describes approaches to assess pharmacokinetics and how drug efflux and uptake transporters impact oral bioavailability• Helps readers reduce the failure rate of drug ... Read more

    $155.00 USD

  • Foundations of Analytical Chemistry

    A Teaching–Learning Approach

    Series series Chemistry and Material Science (R0)
    This book offers a completely new approach to learning and teaching the fundamentals of analytical chemistry. It summarizes 250 basic concepts of the field on the basis of slides. Each of the nine chapters offers the following features:• Introduction: Summary. General scheme. Teaching objectives.• Text containing the explanation of each slide.• Recommended and commented bibliography.• Questions to ... Read more

    $49.49 USD

  • Metabolite Safety in Drug Development

    A reference on drug metabolism and metabolite safety in the development phase, this book reviews the analytical techniques and experimental designs critical for metabolite studies. It features case studies of lessons learned and real world examples, along with regulatory perspectives from the US FDA and EMA.• Reviews the analytical techniques and experimental designs critical for metabolite ... Read more

    $181.00 USD

  • Cardiovascular Diseases

    From Molecular Pharmacology to Evidence-Based Therapeutics

    by Y. Robert Li ...
    Written in an accessible style and consistent format, the book covers both the fundamentals and advances in the pharmacology of cardiovascular drugs, as well as their integrated applications in the management of individual cardiovascular diseases.• Integrates fundamentals and recent advances regarding cardiovascular drugs, blending basic and clinical sciences needed to effectively understand and ... Read more

    $123.00 USD

  • Handbook of Glycomics

    The Handbook of Glycomics provides the first comprehensive overview of the emerging field of glycomics, defined as the study of all complex carbohydrates in an organism or cell ("the glycome"). Beginning with analytic approaches and bioinformatics, this work provides a detailed discussion of relevant databases, data integration, and analysis. It then moves on to a discussion of specific model ... Read more

    $90.89 USD

  • Percutaneous Absorption of UV Filters Contained in Sunscreen Cosmetic Products

    Development of Analytical Methods

    Series series Chemistry and Material Science (R0)
    Zacarías León's thesis describes the development and validation of analytical methods to estimate the processes set in motion by percutaneous absorption of UV filters in sunscreen cosmetic products. León describes these methods in both in vitro and non-invasive in vivo methodologies. Currently dermatologists recommend the use of sunscreen products not only under conditions of extreme exposure to ... Read more

    $89.09 USD