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Showing 1 - 12 of 17 results for “jan barciszewski”
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  • RNA Structure and Function

    Edited by Jan Barciszewski ...
    Series series Biomedical and Life Sciences (R0)
    This book focuses on the current status of our understanding of RNA, a key biological molecule. The various RNAs covered are messenger RNA, ribosomal RNA, transfer RNA, noncoding RNAs, modified nucleosides, and RNA enzymes. The different chapters detail methods to investigate RNA structure and function, the chemistry of modified RNAs, and the latest advances in our understanding of the vast array ... Read more

    $197.09 USD

  • Decoding Aging and Neurodegeneration

    The Role of Nucleic Acid Epigenetics

    Edited by Jan Barciszewski ...
    Series series Biomedical and Life Sciences (R0)
    This book focuses on the close relationship between aging and neurodegeneration. By highlighting the reversible nature of epigenetic changes, it provides a comprehensive overview of how these modifications can regulate gene expression without altering the DNA sequence, offering promising solutions for clinical intervention.Aging induces a gradual decline in cerebral function, leading to cognitive ... Read more

    $251.09 USD

  • Systems Biology II

    Edited by Jan Barciszewski ...
    Series series Biomedical and Life Sciences (R0)
    Modern biology is moving away from reductionist approaches towards holistic studies that encompass whole genomes, transcriptomes, proteomes, and metabolomes. Systems biology is an approach to studying complex biological systems by looking at many biomolecules in a comprehensive way. The aim is to gain a thorough understanding of the biological functions of different classes of molecules and their ... Read more

    $224.09 USD

  • The DNA, RNA, and Histone Methylomes

    Edited by Stefan Jurga, Jan Barciszewski ...
    Series series RNA Technologies
    This book reviews the chemical, regulatory, and physiological mechanisms of protein arginine and lysine methyltransferases, as well as nucleic acid methylations and methylating enzymes. Protein and nucleic acid methylation play key and diverse roles in cellular signalling and regulating macromolecular cell functions.Protein arginine and lysine methyltransferases are the predominant enzymes that ... Read more

    $170.09 USD

  • Epitranscriptomics

    Edited by Stefan Jurga, Jan Barciszewski ...
    Series series Biomedical and Life Sciences (R0)
    This book reviews a novel and exciting field of cellular and molecular biology called epitranscriptomics, which focuses on changes in an organism’s cells resulting from the posttranscriptional modification of cellular RNA. RNA-binding proteins (RBPs) play a crucial role in these posttranscriptional modifications and also support several cellular processes necessary for maintaining RNA homeostasis. ... Read more

    $170.09 USD

  • Messenger RNA Therapeutics

    Edited by Stefan Jurga, Jan Barciszewski ...
    Series series Biomedical and Life Sciences (R0)
    This book focuses on the fundamentals and applications of messenger RNA (mRNA)-based therapeutics and discusses the strengths and key challenges of this emerging class of drugs.In the past 30 years, extensive research and technological development in many areas have contributed to the emergence of in vitro transcribed mRNA as a therapeutic that has now reached clinical testing. Formulations that ... Read more

    $143.09 USD

  • The Chemical Biology of Long Noncoding RNAs

    Edited by Stefan Jurga, Jan Barciszewski ...
    Series Book 11 - RNA Technologies
    This book offers a comprehensive and detailed overview of various aspects of long non-coding RNAs. It discusses their emerging significance in molecular medicine, ranging from human cancers to cardiovascular and metabolic diseases.Transcriptomic studies have demonstrated that the majority of genomes found in complex organisms are expressed in highly dynamic and cell-specific patterns, producing ... Read more

    $143.09 USD

  • Plant Epigenetics

    Edited by Nikolaus Rajewsky, Stefan Jurga, Jan Barciszewski ...
    Series series Biomedical and Life Sciences (R0)
    This book presents, in 26 chapters, the status quo in epigenomic profiling. It discusses how functional information can be indirectly inferred and describes the new approaches that promise functional answers, collectively referred to as epigenome editing. It highlights the latest important advances in our understanding of the functions of plant epigenomics and new technologies for the study of ... Read more

    $188.09 USD

  • Chemical Biology of Nucleic Acids

    Fundamentals and Clinical Applications

    Edited by Wojciech T. Markiewicz, Jan Barciszewski, Volker A. Erdmann ...
    Series series Biomedical and Life Sciences (R0)
    This volume contains 29 engrossing chapters contributed by worldwide, leading research groups in the field of chemical biology. Topics include pre-biology; the establishment of the genetic code; isomerization of RNA; damage of nucleobases in RNA; the dynamic structure of nucleic acids and their analogs in DNA replication, extra- and intra-cellular transport; molecular crowding by the use of ionic ... Read more

    $188.09 USD

  • Therapeutic Ribonucleic Acids in Brain Tumors

    Edited by Guido Reifenberger, Jan Barciszewski, Volker A. Erdmann ...
    Series series Biomedical and Life Sciences (R0)
    In the past few years nucleic acids technologies have grown into a powerful analytical and also increasingly therapeutic tool. It has been applied not only to the uncovering of gene functions in many organisms, but also to pathogenetic analysis and recently also for the treatment of human diseases. The book discusses in depth the potential of these innovative methods in the broad field of central ... Read more

    $188.09 USD

  • RNA and DNA Diagnostics

    Edited by Volker A. Erdmann, Stefan Jurga, Jan Barciszewski ...
    Series series Biomedical and Life Sciences (R0)
    The aim of molecular diagnostics is preferentially to detect a developing disease before any symptoms appear. There has been a significant increase, fueled by technologies from the human genome project, in the availability of nucleic acid sequence information for all living organisms including bacteria and viruses. When combined with a different type of instrumentation applied, the resulting ... Read more

    $89.09 USD

  • From Nucleic Acids Sequences to Molecular Medicine

    Edited by Jan Barciszewski, Volker A. Erdmann ...
    Series series Biomedical and Life Sciences (R0)
    Despite a half century of structural, biophysical and biochemical investigations of ribonucleic acids, they are still mysterious. RNAs stand at fertile crossroads of disciplines, integrating concepts from genomics, proteomics, dynamics as well as biochemistry and molecular biology. From 20 years it is clear, that genetic regulation of eukaryotic organisms has been misunderstood for the last years ... Read more

    $188.09 USD