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  • Myeloid-Derived Suppressor Cells and Cancer

    Series series Biomedical and Life Sciences (R0)
    The book starts with an introduction to and history of myeloid-derived suppressor cells (MDSCs), followed by a description of their differentiation, their role in the tumour microenvironment and their therapeutic targeting. It closes with an outlook on future developments. In cancer patients, myelopoiesis is perturbed and instead of generating immunogenic myeloid cells (such as dendritic cells, ... Read more

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    Edited by Istvan Berczi ...
    New Insights to Neuroimmune Biology investigates the mechanisms that and functions of the Neuroimmune Regulatory Supersystem. Covering molecular regulation of cytokines in brain astrocytes, immunoregulation by the sympathetic nervous system, circadian regulation of immune reactions, antigen recognition by the CNS, the modulation of the immune response by head injury, neurogenic inflammation, the ... Read more

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  • Lentiviral Vectors and Gene Therapy

    Series series Biomedical and Life Sciences (R0)
    Gene therapy was conceived during the early and mid part of the 20th century. At first, it was considered a revolutionary biomedical procedure, which could potentially cure any disease for which the molecular bases were understood. Since then, gene therapy has gone through many stages and has evolved from a nearly unrealistic perspective to a real life application. Clinical efficacy in humans was ... Read more

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  • Anti-Idiotypes, Receptors, and Molecular Mimicry

    Series series Medicine (R0)
    Here is an up-to-date review of important new methods and results in anti-idiotypes, receptors, and molecular mimicry. It begins with a discussion of the theoretical background of the anti-idiotypic network, it's role in the regulation of immune response, and the physical characteristics of anti-idiotypic antibodies. It then goes on to explore many exciting applications in such areas as insulin ... Read more

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  • Semaphorins

    A Diversity of Emerging Physiological and Pathological Activities

    Edited by Atsushi Kumanogoh ...
    Series series Biomedical and Life Sciences (R0)
    This book presents the current concepts of semaphorin biology. In the early 1990s, semaphorins were originally identified as axon guidance cues that function during neuronal development. However, cumulative findings have clarified that they have diverse functions in many physiological processes, including cardiogenesis, angiogenesis, vasculogenesis, osteoclastogenesis, retinal homeostasis, and ... Read more

    $89.09 USD

  • Metallothioneins in Normal and Cancer Cells

    Series series Medicine (R0)
    This book describes the structures of Metallothionein (MT) family members and the cellular functions of MT-1, MT-2 and MT-4 isoforms, as well as provides insights into divergent biological roles of MT-3. The authors explain the involvement of MT molecules in various processes related to carcinogenesis, including an organ-specific presentation of current data concerning their potential impact on ... Read more

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  • Regulation of Cytokine Gene Expression in Immunity and Diseases

    Edited by Xiaojing Ma ...
    Series series Biomedical and Life Sciences (R0)
    This book explores the major cytokines, such as IL-1 and IFN-γ, with respect to the regulation of their gene expression and protein production in specific immune cell types. It discusses both healthy physiological settings and in pathological situations in which the expression of some cytokines could be dysregulated, resulting in either immunodeficiency or exacerbated inflammatory sequelae in ... Read more

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  • Arachidonate Remodeling and Inflammation

    Series series Progress in Inflammation Research
    Arachidonic acid (AA) and other 20 or 22-carbon polyunsaturated fatty acids (PUFAs) are precursors of lipid mediators of inflammation known as eicosanoids. These mediators are critical in disease processes and in regulating normal cell function. Remodeling is important in maintaining homeostasis and in regulating cell function by dictating how PUFAs are converted to lipid mediators of inflammation ... Read more

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  • Immunoassays in Coagulation Testing

    by Z. Parvez ...
    Series series Medicine (R0)
    Rapid progress in analytical methods, within the past few decades, has led to the widespread applications of newer immunological and radioimmunoassay techniques to the diagnosis and treatment of hemorrhagic and thrombotic disorders. Major advances were made to meet the multiple challenges of improving precision, accuracy, and availability of various measurements. These advances have been ... Read more

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  • Cell Biology of Herpes Viruses

    Edited by Klaus Osterrieder ...
    Series Book 223 - Advances in Anatomy, Embryology and Cell Biology
    Herpes viruses are widely distributed in nature, causing disease in organisms as diverse as bivalves and primates, including humans. Each virus appears to have established a long-standing relationship with its host, and the viruses have the ability to manipulate and control the metabolism of host cells, as well as innate and adaptive antiviral immune responses. Herpes viruses maintain themselves ... Read more

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  • The Chemokine Factsbook

    Ligands and Receptors

    Series series Factsbook
    How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, amino acid sequences, gene organization? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact? The Academic Press FactsBook series will satisfy scientists and clinical researchers suffering from information overload. ... Read more

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  • New Aspects in the Diagnosis and Treatment of Hodgkin’s Disease

    First International Symposium on Hodgkin's Lymphoma in Cologne, October 2-3, 1987

    Series series Medicine (R0)
    In the field of Hodgkin's lymphoma, many new data have been collected during the last decade both on the cell of origin of this disease and on more effective therapies to cure the majority of pa tients even in the advanced stages. Therefore, it seems to be justi fied to compile these new data in a special volume of Recent Re sults in Cancer Research. This volume summarizes the contribu tions ... Read more

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