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  • Immunity, Tumors and Aging: The Role of HSP70

    by Igor Malyshev ...
    Series series Biomedical and Life Sciences (R0)
    The book is dedicated to the topical area of biology and medicine and the role of stress proteins HSP70 in the regulation of intracellular protein homeostasis, signaling transduction and cell protection. The book is divided into chapters, which describe the discovery of HSP70 and its molecular structure, the mechanism of the synthesis and function in normal and damaged cells, examine the role of ... Read more

    $49.49 USD

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    How will increased understanding of the human genome affect our ability to diagnose and treat disease? The subject of recombinant DNA technology is no longer limited to the research laboratory; it is being discussed in ever-widening medical circles. Introduction to Molecular Medicine is especially written for the physician who is not a genetics expert but wishes to understand this new science and ... Read more

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  • Semaphorins

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    Edited by Atsushi Kumanogoh ...
    Series series Biomedical and Life Sciences (R0)
    This book presents the current concepts of semaphorin biology. In the early 1990s, semaphorins were originally identified as axon guidance cues that function during neuronal development. However, cumulative findings have clarified that they have diverse functions in many physiological processes, including cardiogenesis, angiogenesis, vasculogenesis, osteoclastogenesis, retinal homeostasis, and ... Read more

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  • Therapeutic Vaccination Strategies

    Edited by P. Walden, W. Sterry, H. Hennekes ...
    Series series Medicine (R0)
    The induction of immune responses against tumor cells by vaccination is rapidly evolving as a therapeutic modality with new potentials for the treatment of cancer. It is based on the fact that our immune system can identify tumor cells and, once activated, is capable of developing specific immunity against the neoplastic cells. Numerous observations and intense research clearly document the major ... Read more

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  • Introduction to Gastrointestinal Diseases Vol. 2

    Edited by Jakub Fichna ...
    Series series Medicine (R0)
    Learn the basics and more of gastrointestinal diseases.Gastrointestinal diseases have become a major medical, social and economic burden worldwide. The larger the number of patients suffering from gastric ulcer and colorectal cancer, the greater the need to properly diagnose and cure.This book is a comprehensive guide through GI diseases, which can be used by practitioners and patients. It will ... Read more

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  • Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy

    Edited by Emmanuel Donnadieu ...
    Series series Biomedical and Life Sciences (R0)
    This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important ... Read more

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  • Organelle Contact Sites

    From Molecular Mechanism to Disease

    Edited by Thomas Simmen, Mitsuo Tagaya ...
    Series series Biomedical and Life Sciences (R0)
    This book provides the first comprehensive coverage of the quickly evolving research field of membrane contact sites (MCS). A total of 16 chapters explain their organization and role and unveil the significance of MCS for various diseases.MCS, the intracellular structures where organellar membranes come in close contact with one another, mediate the exchange of proteins, lipids, and ions. Via ... Read more

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  • Metastasis of Colorectal Cancer

    Series series Biomedical and Life Sciences (R0)
    Colorectal cancer is the third most common cancer worldwide, and in many parts of the western world, it is the second leading cause of cancer-related deaths.This book covers colon cancer metastasis from the most fundamental aspects to clinical practice. Major topics include physiopathology, genetic and epigenetic controls, cancer initiating cells, epithelial-mesenchymal transition, growth factors ... Read more

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  • Molecular Mechanisms of Bacterial Infection via the Gut

    Edited by Chihiro Sasakawa ...
    Series Book 337 - Current Topics in Microbiology and Immunology
    Our gut is colonized by numerous bacteria throughout our life, and the gut epithelium is constantly exposed to foreign microbes and dietary antigens. Thus, the gut epithelium acts as a barrier against microbial invaders and is equipped with various innate defense systems. Resident commensal and foreign invading bacteria interact intimately with the gut epithelium and can impact host cellular and ... Read more

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    Edited by Catherine M. Greene ...
    Series series Progress in Inflammation Research
    The book serves as a comprehensive resource for scientists and clinicians studying the role of non-coding RNAs in inflammation (viral infections, wound inflammation), human inflammatory diseases (i.e. rheumatoid arthritis, Crohn’s disease, diabetes) and innate immunity. It provides a universal reference work comprising both basic and specialized information. Given that ncRNAs represent new ... Read more

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  • Molecular Vaccines

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    Edited by Matthias Giese ...
    Series series Biomedical and Life Sciences (R0)
    This title discusses all aspects of non-infectious and non-cancer– so called NINC – vaccines. Hypertension, diabetes and allergy vaccine development are referred to as well as the use of adjuvants and nanotechnology in vaccine development. The way of novel vaccines from bench to preclinical to clinical studies and launch to the market under EMEA (European Medicines Agency) and FDA (Food and Drug ... Read more

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  • Intrinsic Immunity

    Edited by Bryan R. Cullen ...
    Series series Biomedical and Life Sciences (R0)
    Recent research has focused attention on the importance of intrinsic antiviral immunity, i.e. immunity mediated by factors that are constitutively expressed in many cells. In this volume, leading experts provide a comprehensive overview of this relatively new and rapidly evolving field. They cover intrinsic proteinaceous antiviral immune effectors, such as the APOBEC3 and TRIM protein families as ... Read more

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