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Showing 1 - 12 of 12 results for “grazyna kochan”
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  • Lentiviral Vectors and Gene Therapy

    by David Escors, Karine Breckpot, Frederick Arce, Grazyna Kochan, Holly Stephenson ...
    Series series Biomedical and Life Sciences (R0)
    Gene therapy was conceived during the early and mid part of the 20th century. At first, it was considered a revolutionary biomedical procedure, which could potentially cure any disease for which the molecular bases were understood. Since then, gene therapy has gone through many stages and has evolved from a nearly unrealistic perspective to a real life application. Clinical efficacy in humans was ... Read more

    $49.49 USD

  • Myeloid-Derived Suppressor Cells and Cancer

    by David Escors, Grazyna Kochan, James E. Talmadge, Jo A. Van Ginderachter, Karine Breckpot ...
    Series series Biomedical and Life Sciences (R0)
    The book starts with an introduction to and history of myeloid-derived suppressor cells (MDSCs), followed by a description of their differentiation, their role in the tumour microenvironment and their therapeutic targeting. It closes with an outlook on future developments. In cancer patients, myelopoiesis is perturbed and instead of generating immunogenic myeloid cells (such as dendritic cells, ... Read more

    $49.49 USD

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  • Regulation of Cytokine Gene Expression in Immunity and Diseases

    Edited by Xiaojing Ma ...
    Series series Biomedical and Life Sciences (R0)
    This book explores the major cytokines, such as IL-1 and IFN-γ, with respect to the regulation of their gene expression and protein production in specific immune cell types. It discusses both healthy physiological settings and in pathological situations in which the expression of some cytokines could be dysregulated, resulting in either immunodeficiency or exacerbated inflammatory sequelae in ... Read more

    $143.09 USD

  • Jak-Stat Signaling : From Basics to Disease

    Edited by Thomas Decker, Mathias Müller ...
    Series series Biomedical and Life Sciences (R0)
    JAK tyrosine kinases and STAT transcription factors constitute a signaling pathway, which is activated by cytokines. By activating gene transcription it regulates essential biological responses to environmental cues. The Jak-Stat pathway is involved in the regulation of cell development, differentiation, proliferation and apoptosis. Improper function may contribute to hematopoietic malignancies ... Read more

    $143.09 USD

  • Perspectives in Translational Research in Life Sciences and Biomedicine

    Translational Outcomes Research in Life Sciences and Translational Medicine, Volume 1

    by Ena Ray Banerjee ...
    Series series Biomedical and Life Sciences (R0)
    The present book addresses the multi-disciplinary nature of Translational Outcomes Research, which is a watershed for nearly all the disciplines of Life and Health Sciences, along with the Materials Sciences including but not limited to Zoology, Botany, Microbiology, Biochemistry, Physiology, Nanotechnology, the Medical Sciences, Bioengineering, Biophysics, Medicinal Chemistry, Structural Biology, ... Read more

    $143.09 USD

  • Viral Genome Replication

    Edited by Craig E. Cameron, Matthias Gotte, Kevin Raney ...
    Series series Biomedical and Life Sciences (R0)

    $188.09 USD

  • Tumor-Induced Immune Suppression

    Mechanisms and Therapeutic Reversal

    Edited by Dmitry I. Gabrilovich, Arthur Andrew Hurwitz ...
    Series series Biomedical and Life Sciences (R0)
    Tumor-Induced Immune Suppression - Prospects and Progress in Mechanisms and Therapeutic Reversalpresents a comprehensive overview of large number of different mechanisms of immune dysfunction in cancer and therapeutic approaches to their correction. This includes the number of novel mechanisms that has never before been discussed in previous monographs.The last decades were characterized by ... Read more

    $188.09 USD

  • Interleukin-10 in Health and Disease

    Edited by Anne O'Garra, Simon Fillatreau ...
    Series series Biomedical and Life Sciences (R0)
    This volume provides a set of reviews dedicated to the biology of Interleukin (IL)-10. It includes chapters on its importance for maintaining immune homeostasis in humans, its role in intestinal immunity and its functions during viral and bacterial infections. In addition, it presents reviews on the mechanisms linking innate microbial recognition to the production of IL-10 and on how IL-10 ... Read more

    $89.09 USD

  • Introduction to Molecular Medicine

    by Dennis W. Ross ...
    How will increased understanding of the human genome affect our ability to diagnose and treat disease? The subject of recombinant DNA technology is no longer limited to the research laboratory; it is being discussed in ever-widening medical circles. Introduction to Molecular Medicine is especially written for the physician who is not a genetics expert but wishes to understand this new science and ... Read more

    $80.09 USD

  • New Insights to Neuroimmune Biology

    Edited by Istvan Berczi ...
    New Insights to Neuroimmune Biology investigates the mechanisms that and functions of the Neuroimmune Regulatory Supersystem. Covering molecular regulation of cytokines in brain astrocytes, immunoregulation by the sympathetic nervous system, circadian regulation of immune reactions, antigen recognition by the CNS, the modulation of the immune response by head injury, neurogenic inflammation, the ... Read more

    $152.99 USD

  • Decoding the Antibody Repertoire

    High Throughput Sequencing of Multiple Transcripts from Single B Cells

    by Brandon DeKosky ...
    Series series Biomedical and Life Sciences (R0)
    This thesis outlines the development of the very first technology for high-throughput analysis of paired heavy and light-chain antibody sequences, opening an entirely new window for antibody discovery and the investigation of adaptive immune responses to vaccines and diseases.Previous methods for high-throughput immune repertoire sequencing have been unable to provide information on the identity ... Read more

    $89.09 USD

  • Anti-Idiotypes, Receptors, and Molecular Mimicry

    Edited by D. Scott Linthicum, Nadir R. Farid ...
    Series series Medicine (R0)
    Here is an up-to-date review of important new methods and results in anti-idiotypes, receptors, and molecular mimicry. It begins with a discussion of the theoretical background of the anti-idiotypic network, it's role in the regulation of immune response, and the physical characteristics of anti-idiotypic antibodies. It then goes on to explore many exciting applications in such areas as insulin ... Read more

    $49.49 USD