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Showing 1 - 12 of 12 results for “fred gage”
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  • Genome Editing in Neurosciences

    Edited by Rudolf Jaenisch, Feng Zhang, Fred Gage ...
    Series series Research and Perspectives in Neurosciences
    This book is open access under a CC BY 4.0 license.CRISPR-Cas9 is a rapid, efficient, versatile and relatively cheap method for dissecting the molecular pathways that are the basis of life, as well as for investigating and potentially rectifying faults in these pathways that result in disease.This book reviews how CRISPR-Cas9 and other genome editing techniques are advancing our understanding of ... Read more

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  • Parkinson's Disease

    Molecular and Therapeutic Insights From Model Systems

    Edited by Richard Nass, Serge Przedborski ...
    Parkinson's disease is the second most prevalent neurodegenerative disease and is characterized by the irreversible loss of dopamine neurons. Despite its high prevalence in society and many decades of research, the origin of the pathogenesis and the molecular determinants involved in the disorder has remained elusive. Confounding this issue is the lack of experimental models that completely ... Read more

    $139.49 USD

  • Epigenetic Regulation and Epigenomics

    Edited by Robert A. Meyers ...
    Series series Advances in Molecular Biology and Medicine
    Epigenetics is a term in biology referring to heritable traits that do not involve changes in the underlying DNA sequence of the organism. Epigenetic traits exist on top of or in addition to the traditional molecular basis for inheritance. The "epigenome" is a parallel to the word "genome," and refers to the overall epigenetic state of a cell. Cancer and stem cell research have gradually focused ... Read more

    $342.00 USD

  • Advances in Nucleic Acid Therapeutics

    Edited by Sudhir Agrawal, Michael J Gait ...
    Series Book 68 - Drug Discovery Series
    The sequencing of the human genome and subsequent elucidation of the molecular pathways that are important in the pathology of disease have provided unprecedented opportunities for the development of new therapeutics. Nucleic acid-based drugs have emerged in recent years to yield extremely promising candidates for drug therapy to a wide range of diseases. Advances in Nucleic Acid Therapeutics is a ... Read more

    $247.99 USD

  • Handbook of Epigenetics

    The New Molecular and Medical Genetics

    Edited by Trygve O. Tollefsbol ...
    Handbook of Epigenetics: The New Molecular and Medical Genetics, Second Edition, provides a comprehensive analysis of epigenetics, from basic biology, to clinical application. Epigenetics is considered by many to be the new genetics in that many biological phenomena are controlled, not through gene mutations, but rather through reversible and heritable epigenetic processes. These epigenetic ... Read more

    $179.99 USD

  • The Molecular and Cellular Basis of Neurodegenerative Diseases

    Underlying Mechanisms

    Edited by Michael S. Wolfe ...
    The Molecular and Cellular Basis of Neurodegenerative Diseases: Underlying Mechanisms presents the pathology, genetics, biochemistry and cell biology of the major human neurodegenerative diseases, including Alzheimer's, Parkinson's, frontotemporal dementia, ALS, Huntington's, and prion diseases. Edited and authored by internationally recognized leaders in the field, the book's chapters explore ... Read more

    $89.99 USD

  • Medicinal Chemistry Approaches to Personalized Medicine

    by Raimund Mannhold, Hugo Kubinyi, Gerd Folkers ...
    Series Book 59 - Methods & Principles in Medicinal Chemistry
    Edited by two renowned medicinal chemists who have pioneered the development of personalized therapies in their respective fields, this authoritative analysis of what is already possible is the first of its kind, and the only one to focus on drug development issues.Numerous case studies from the first generation of "personalized drugs" are presented, highlighting the challenges and opportunities ... Read more

    $126.00 USD

  • Advances in Genome Science Volume 1: Changing Views on Living Organisms

    by Christian Neri ...
    Genome science or genomics is essential to advancing knowledge in the fields of biology and medicine. Specifically, researchers learn about the molecular biology behind genetic expression in living organisms and related methods of treating human genetic diseases (including gene therapy). Advances in Genome Science is an e-book series which provides a multi-disciplinary view of some of the latest ... Read more

    $71.99 USD

  • Handbook of Epigenetics

    The New Molecular and Medical Genetics

    Edited by Trygve O. Tollefsbol ...
    Handbook of Epigenetics: The New Molecular and Medical Genetics, Third Edition provides a comprehensive analysis of epigenetics, from basic biology to clinical application. This new edition has been fully revised to cover the latest and evolving topics in epigenetics, with chapters updated and new chapters added on topics such as single-cell epigenetics, DNA methylation clocks in age-related ... Read more

    $202.49 USD

  • Cancer Stem Cells

    by Vinagolu K. Rajasekhar ...
    Cancer Stem Cells covers a wide range of topics in cancer stem cell biology, including the functional characteristics of cancer stem cells and how they're generated, where they are localized, the means by which cancer stem cells can be targeted, and how cancer stem cells can be reprogrammed back to normal tissue stem cells. Each chapter begins with a brief historical note and concept summary, ... Read more

    $178.00 USD

  • Handbook of the Biology of Aging

    Edited by Nicolas Musi, Peter Hornsby ...
    Series series Handbooks of Aging
    Handbook of the Biology of Aging, Ninth Edition, provides a comprehensive synthesis and review of the latest and most important advances and themes in modern biogerontology. The book focuses on the trend of 'big data' approaches in the biological sciences, presenting new strategies to analyze, interpret and understand the enormous amounts of information being generated through DNA sequencing, ... Read more

    $112.49 USD

  • Epigenetics in Human Disease

    Edited by Trygve O. Tollefsbol ...
    Series series Translational Epigenetics
    Epigenetics in Human Disease, Second Edition examines the diseases and conditions on which we have advanced knowledge of epigenetic mechanisms, such as cancer, autoimmune disorders, aging, metabolic disorders, neurobiological disorders and cardiovascular disease. In addition to detailing the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, novel ... Read more

    $157.49 USD