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  • Advances in TNF Family Research

    Proceedings of the 12th International TNF Conference, 2009

    Series series Springer Nature Proceedings excluding Computer Science
    The biennial TNF-family conferences have been held over the past 20 years, from the time that TNF was cloned. These meetings have followed the enormous progress in this field. Much is now known about the members of the TNF ligand and receptor families, their signaling proteins, mechanisms of action and cellular functions. This volume is the proceedings of the 12th TNF International Conference, ... Read more

    $287.09 USD

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    Volume 1: Immunotoxicology, Immunopathology, and Immunotherapy

    Edited by M. A. Hayat ...
    Immunology, Volume 1: Immunotoxicology, Immunopathology, and Immunotherapy discusses the investment of time, effort and finance that go into making progress in preventing and/or curing serious diseases by using standard treatments (chemotherapy, radiotherapy, surgery, and hormone therapy). The use of these treatments is accompanied by unavoidable, devastating side effects. At the cost of being ... Read more

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  • Antibiotics – Are They Curing Us or Killing Us?

    The Catastrophic Impact of the Over-prescription of Antibiotics on Our Health

    by John McKenna ...
    Antibiotics: Are they curing us or killing us? 'Without urgent, co-ordinated action by many stakeholders, the world is headed for a post-antibiotic era, in which common infections and minor injuries which have been treatable for decades can once again kill.' Dr Keiji Fukuda, World Health Organization For anyone reeling from this recent, shocking statement from WHO, Dr John McKenna is here to help. ... Read more

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  • Pathogenesis of Mycobacterium tuberculosis and its Interaction with the Host Organism

    Series series Biomedical and Life Sciences (R0)
    Mycobacterium tuberculosis is one of the most notorious pathogens on earth, causing the death of approximately 1.5 million people annually. A major problem in the fight against tuberculosis is the emergence of strains that have acquired resistance to all available antibiotics. One key to the success of M. tuberculosis as a pathogen is its ability to circumvent host immune responses at different ... Read more

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  • Intrinsic Immunity

    Edited by Bryan R. Cullen ...
    Series series Biomedical and Life Sciences (R0)
    Recent research has focused attention on the importance of intrinsic antiviral immunity, i.e. immunity mediated by factors that are constitutively expressed in many cells. In this volume, leading experts provide a comprehensive overview of this relatively new and rapidly evolving field. They cover intrinsic proteinaceous antiviral immune effectors, such as the APOBEC3 and TRIM protein families as ... Read more

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  • Listen to the Music

    The Life of Hilary Koprowski

    by Roger Vaughan ...
    Series series Biomedical and Life Sciences (R0)
    Dr. Hilary Koprowski is the pioneer of live polio vaccine, the first researcher to advance the diagnostic and therapeutic use of monoclonal antibodies, and the developer of the "gold standard" rabies vaccine. This biography chronicles his distinguished career and life's work in the field of microbiology. A world-reknowned maverick in biomedical research, Koprowski's research methods were often ... Read more

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  • West Nile Encephalitis Virus Infection

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    Edited by Michael S. Diamond ...
    Series series Biomedical and Life Sciences (R0)
    West Nile virus is a neurotropic flavivirus that has emerged globally as a primary cause of viral encephalitis. Infection of humans and other vertebrate animals is associated with a febrile illness that can progress to a lethal encephalitis or flaccid paralysis syndrome. Its appearance in the Western Hemisphere in 1999 and the corresponding increase in global disease burden over the last decade ... Read more

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  • Inorganic Polyphosphates in Eukaryotic Cells

    The book elucidates the role of inorganic polyphosphates in eukaryotic cells, from fungi and protozoa to human being. To date, there is plenty of evidence that these anionic biopolymers occurring in the cells of all living organisms, from bacteria to humans, perform numerous regulatory functions. The book describes the evolution of PolyPs, their role in lower eukaryotes and their involvement in ... Read more

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  • Organelle Contact Sites

    From Molecular Mechanism to Disease

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    Series series Biomedical and Life Sciences (R0)
    This book provides the first comprehensive coverage of the quickly evolving research field of membrane contact sites (MCS). A total of 16 chapters explain their organization and role and unveil the significance of MCS for various diseases.MCS, the intracellular structures where organellar membranes come in close contact with one another, mediate the exchange of proteins, lipids, and ions. Via ... Read more

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    Series series Biomedical and Life Sciences (R0)
    In 1898, an Austrian microbiologist Heinrich Winterberg made a curious observation: the number of microbial cells in his samples did not match the number of colonies formed on nutrient media (Winterberg 1898). About a decade later, J. Amann qu- tified this mismatch, which turned out to be surprisingly large, with non-growing cells outnumbering the cultivable ones almost 150 times (Amann 1911). ... Read more

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    From Pre-Clinical Development to Therapeutic Applications

    Edited by Gail Lewis Phillips ...
    Series series Cancer Drug Discovery and Development
    This volume gathers the leading research on antibody-drug conjugates and immunotoxins. Following a rigorous overview, the volume delves into focused sections on all aspects of ADCs and ITs from clinical development through to targeted therapeutic applications and the latest technologies. ... Read more

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  • Infection and Cancer: Bi-Directorial Interactions

    This unique book summarizes current knowledge on co-development of infectious diseases and cancer. It provides an overview of the complex and unique role of the immune system, inflammation, tumor-mediated immunosuppression and infection-induced immunomodulation in cancer and infection progression.Chapters are organized into themed parts, beginning with a look at the historical perspective of human ... Read more

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