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Chemistry and Pharmacology of Anticancer Drugs

by David E. Thurston, Ilona Pysz ...

While drug therapies developed in the last 80 years have markedly improved treatment outcomes and the management of some types of cancers, the lack of effectiveness and side effects associated with the most common treatment types remain unacceptable. However, recent technological advances are leading to improved therapies based on targeting distinct biological pathways in cancer cells. Chemistry ... Read more

$189.99 USD

While drug therapies developed in the last 80 years have markedly improved treatment outcomes and the management of some types of cancers, the lack of effectiveness and side effects associated with the most common treatment types remain unacceptable. However, recent technological advances are leading to improved therapies based on targeting distinct biological pathways in cancer cells. Chemistry
... Read more
Drug Discovery for Schizophrenia

From PNS to CNS and Back

by David Thurston ...

Series Book 84 - Drug Discovery Series
Following progress in schizophrenia since 2015, this new volume covers the advancing knowledge of scientists and clinicians in drug discovery. The book enhances our understanding of pathological neural communication between the peripheral nervous system (PNS) and central nervous system (CNS) in patients with schizophrenia. Although 75% of neural information passes through the PNS, interactions ... Read more

$211.49 USD

Following progress in schizophrenia since 2015, this new volume covers the advancing knowledge of scientists and clinicians in drug discovery. The book enhances our understanding of pathological neural communication between the peripheral nervous system (PNS) and central nervous system (CNS) in patients with schizophrenia. Although 75% of neural information passes through the PNS, interactions
... Read more
Journeys in the Wild

From award-winning cameraman for David Attenborough's ‘A Life on Our Planet'

by Gavin Thurston ...

'Modest, down to earth and full of humour, this is one of the best books about filming I've ever read.' MICHAEL PALIN'Extraordinary: Gavin's easy prose and gasp-making encounters make for a gripping and very funny read. It's a rollercoaster ride with a complete professional. I loved it.' JOANNA LUMLEY'[Gavin is] a great cameraman with infinite patience, but also a writer with great powers of ... Read more

$4.99 USD

'Modest, down to earth and full of humour, this is one of the best books about filming I've ever read.' MICHAEL PALIN'Extraordinary: Gavin's easy prose and gasp-making encounters make for a gripping and very funny read. It's a rollercoaster ride with a complete professional. I loved it.' JOANNA LUMLEY'[Gavin is] a great cameraman with infinite patience, but also a writer with great powers of
... Read more
Sustainable Practices For Plant Disease Management In Traditional Farming Systems

by H. David Thurston ...

Most scientists and many of the world's farmers have abandoned traditional farming practices and systems in an effort to increase production and to improve the efficiency of land and labor use. The resulting "modern" systems largely ignore many of the sustainable pest management practices that have evolved among farmers over centuries. In this book ... Read more

$55.99 USD

Most scientists and many of the world's farmers have abandoned traditional farming practices and systems in an effort to increase production and to improve the efficiency of land and labor use. The resulting "modern" systems largely ignore many of the sustainable pest management practices that have evolved among farmers over centuries. In this book
... Read more
Cytotoxic Payloads for Antibody–Drug Conjugates

Edited by Paul J M Jackson, David Thurston ...

Series Book 71 - Drug Discovery Series
Antibody–drug conjugates (ADCs) represent one of the most promising and exciting areas of anticancer drug discovery. Five ADCs are now approved in the US and EU [i.e., ado-trastuzumab emtansine (Kadcyla™), brentuximab vedotin (Adcetris™), inotuzumab ozogamicin (Besponsa™), gemtuzumab ozogamicin (Mylotarg™) and moxetumomab pasudotox-tdfk (Lumoxiti®)] and over 70 others are in various stages of ... Read more

$224.99 USD

Antibody–drug conjugates (ADCs) represent one of the most promising and exciting areas of anticancer drug discovery. Five ADCs are now approved in the US and EU [i.e., ado-trastuzumab emtansine (Kadcyla™), brentuximab vedotin (Adcetris™), inotuzumab ozogamicin (Besponsa™), gemtuzumab ozogamicin (Mylotarg™) and moxetumomab pasudotox-tdfk (Lumoxiti®)] and over 70 others are in various stages of
... Read more
Small-molecule Transcription Factor Inhibitors in Oncology

Edited by Khondaker Miraz Rahman, David Thurston ...

Series Book 65 - Drug Discovery Series
Oncogenic transcription factors are an increasingly important target for anticancer therapies. Inhibiting these transcription factors could allow tumour cells to be "reprogrammed", leading to apoptosis or differentiation from the malignant phenotype. As the use of kinase inhibitors is gradually declining, transcription factor inhibition is the next hot topic for oncology research and merits much ... Read more

$188.09 USD

Oncogenic transcription factors are an increasingly important target for anticancer therapies. Inhibiting these transcription factors could allow tumour cells to be "reprogrammed", leading to apoptosis or differentiation from the malignant phenotype. As the use of kinase inhibitors is gradually declining, transcription factor inhibition is the next hot topic for oncology research and merits much
... Read more
Indigenous Homelessness

Perspectives from Canada, Australia, and New Zealand

by Paul Andrew, Tim Aubry, Yale Belanger, Cynthia Bird, Christina Birdsall-Jones, Marleny M. Bonnycastle, Deidre Brown, Rebecca Cherner, Patricia Franks, Susan Farrell0, Joshua Freistadt1, Charmaine Green2, Kelly Greenop3, Shiloh Groot4, Darrin Hodgetts5, Selena Kern6, Pita Richard Wiremu King7, Fran Klodawsky8, Gabrielle Lindstrom9, Paul Memmott0, Daphne Nash1, Julia Parrel2, Sarah Prout3, Mohi Rua4, Rebecca Schiff5, Rebecca Schiff6, Annette Siddle7, Maureen Simpkins8, Barbara A. Smith9, Wilfreda E. Thurston0, Alina Turner1, David Turner2, Jeanette Waegemakers Schiff3, Tiniwai Chas Te Whetu4, Rob Willetts5 ...

Being homeless in one’s homeland is a colonial legacy for many Indigenous people in settler societies. The construction of Commonwealth nation-states from colonial settler societies depended on the dispossession of Indigenous peoples from their lands. The legacy of that dispossession and related attempts at assimilation that disrupted Indigenous practices, languages, and cultures—including ... Read more

$17.99 USD

Being homeless in one’s homeland is a colonial legacy for many Indigenous people in settler societies. The construction of Commonwealth nation-states from colonial settler societies depended on the dispossession of Indigenous peoples from their lands. The legacy of that dispossession and related attempts at assimilation that disrupted Indigenous practices, languages, and cultures—including
... Read more
Audiobook

Audiobook

The Genius Plague

by David Walton ...

Narrated by Nick Thurston ...

Unabridged

14 hours 34 min

The contagion is in your mind.In this science fiction thriller, brothers are pitted against each other as a pandemic threatens to destabilize world governments by exerting a subtle mind control over survivors.Neil Johns has just started his dream job as a code breaker for the NSA when his brother Paul, a mycologist, goes missing on a trip to collect samples in the Amazon jungle. Paul returns with ... Read more

$22.95 USD or Free with Kobo Plus

Also available as: eBook

The contagion is in your mind.In this science fiction thriller, brothers are pitted against each other as a pandemic threatens to destabilize world governments by exerting a subtle mind control over survivors.Neil Johns has just started his dream job as a code breaker for the NSA when his brother Paul, a mycologist, goes missing on a trip to collect samples in the Amazon jungle. Paul returns with
... Read more

Also available as: eBook
Audiobook

Audiobook

When Animals Dream

The Hidden World of Animal Consciousness

by David M. Pena-Guzman ...

Narrated by Charlie Thurston ...

Unabridged

5 hours 14 min

Are humans the only dreamers on Earth? What goes on in the minds of animals when they sleep? When Animals Dream brings together behavioral and neuroscientific research on animal sleep with philosophical theories of dreaming. It shows that dreams provide an invaluable window into the cognitive and emotional lives of nonhuman animals, giving us access to a seemingly inaccessible realm of animal ... Read more

$18.99 USD or Free with Kobo Plus

Are humans the only dreamers on Earth? What goes on in the minds of animals when they sleep? When Animals Dream brings together behavioral and neuroscientific research on animal sleep with philosophical theories of dreaming. It shows that dreams provide an invaluable window into the cognitive and emotional lives of nonhuman animals, giving us access to a seemingly inaccessible realm of animal
... Read more
Audiobook

Audiobook

Journeys in the Wild

The Secret Life of a Cameraman

by Gavin Thurston ...

Narrated by Gavin Thurston ...

Unabridged

12 hours 52 min

From Gavin Thurston, the award-winning Blue Planet II and Planet Earth II cameraman, comes extraordinary and adventurous true stories of what it takes to track down and film our planet's most captivating creatures.Gavin has been a wildlife photographer for over thirty years. During that time he's lurked in the shadows of some of the world's remotest places in order to capture footage of the animal ... Read more

$24.99 USD

From Gavin Thurston, the award-winning Blue Planet II and Planet Earth II cameraman, comes extraordinary and adventurous true stories of what it takes to track down and film our planet's most captivating creatures.Gavin has been a wildlife photographer for over thirty years. During that time he's lurked in the shadows of some of the world's remotest places in order to capture footage of the animal
... Read more
Audiobook

Audiobook

The Rise and Fall of D.O.D.O.

A Novel

by Neal Stephenson, Nicole Galland ...

Narrated by Laurence Bouvard, Shelley Atkinson, Laural Merlington, Joe Barrett, Will Damron, Luke Daniels, Robert Fass, Tavia Gilbert, Arthur Morey, David Stifel, Charlie Thurston, Kate Udall, James Anderson Foster ...

Unabridged

24 hours 27 min

This full cast recording features narration from Arthur Morey; Charlie Thurston; David Stifel; James Anderson Foster; Joe Barrett; Kate Udall; Laural Merlington; Laurence Bouvard; Luke Daniels; Robert Fass; Shelley Atkinson; Tavia Gilbert; and Will DamronFrom bestselling author Neal Stephenson and critically acclaimed historical and contemporary commercial novelist Nicole Galland comes a ... Read more

$52.99 USD

Also available as: eBook

This full cast recording features narration from Arthur Morey; Charlie Thurston; David Stifel; James Anderson Foster; Joe Barrett; Kate Udall; Laural Merlington; Laurence Bouvard; Luke Daniels; Robert Fass; Shelley Atkinson; Tavia Gilbert; and Will DamronFrom bestselling author Neal Stephenson and critically acclaimed historical and contemporary commercial novelist Nicole Galland comes a
... Read more

Also available as: eBook
Audiobook

Audiobook

The Weight of Air

A Story of the Lies About Addiction and the Truth About Recovery

by David Poses ...

Narrated by Charlie Thurston ...

Unabridged

8 hours 7 min

While his wife and two-year-old daughter watched TV in the living room, David Poses was in the kitchen, measuring the distance from his index finger to his armpit. He needed to be sure he could pull the trigger with a shotgun barrel in his mouth. Twenty-six inches. Thirty-two years old. More than a decade in a double life fueled by depression and heroin.In his groundbreaking memoir, The Weight of ... Read more

$20.99 USD or Free with Kobo Plus

While his wife and two-year-old daughter watched TV in the living room, David Poses was in the kitchen, measuring the distance from his index finger to his armpit. He needed to be sure he could pull the trigger with a shotgun barrel in his mouth. Twenty-six inches. Thirty-two years old. More than a decade in a double life fueled by depression and heroin.In his groundbreaking memoir, The Weight of
... Read more

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Top Series in United States

Drug Discovery Series

Drug Discovery Series

Drug Discovery Series

Chemistry and Pharmacology of Anticancer Drugs

Drug Discovery for Schizophrenia

Journeys in the Wild

Sustainable Practices For Plant Disease Management In Traditional Farming Systems

Cytotoxic Payloads for Antibody–Drug Conjugates

Small-molecule Transcription Factor Inhibitors in Oncology

Indigenous Homelessness

The Genius Plague

When Animals Dream

Journeys in the Wild

The Rise and Fall of D.O.D.O.

The Weight of Air

eReaders

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Shopping Cart

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Top Series in United States

Drug Discovery Series

Drug Discovery Series

Drug Discovery Series

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