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  • Covering Politics in the Age of Trump

    Like politics, journalism has been turned topsy-turvy by the presidency of Donald Trump. Covering Politics in the Age of Trump takes a wide-ranging view of the relationship between the forty-fifth president and the Fourth Estate. In concise, illuminating, and often personal essays, twenty-four top journalists address topics such as growing concerns about political bias and journalistic objectivity ... Read more

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  • Development of Innovative Drugs via Modeling with MATLAB

    A Practical Guide

    Series series Biomedical and Life Sciences (R0)
    The development of innovative drugs is becoming more difficult while relying on empirical approaches. This inspired all major pharmaceutical companies to pursue alternative model-based paradigms. The key question is: How to find innovative compounds and, subsequently, appropriate dosage regimens?Written from the industry perspective and based on many years of experience, this book offers:- ... Read more

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  • Advanced Drug Delivery

    Provides both fundamentals and new and emerging applicationsAdvanced Drug Delivery brings readers fully up to date with the state of the science, presenting the basics, formulation strategies, and therapeutic applications of advanced drug delivery. The book demonstrates how core concepts of pharmaceutical sciences, chemistry, and molecular biology can be combined and applied in order to spark ... Read more

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  • Quantitative Decisions in Drug Development

    Series series Springer Series in Pharmaceutical Statistics
    This book offers a high-level treatise of evidence-based decisions in drug development. Because of the inseparable relationship between designs and decisions, a good portion of this book is devoted to the design of clinical trials. The book begins with an overview of product development and regulatory approval pathways. It then discusses how to incorporate prior knowledge into study design and ... Read more

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  • Group Sequential and Confirmatory Adaptive Designs in Clinical Trials

    Series series Mathematics and Statistics (R0)
    This book provides an up-to-date review of the general principles of and techniques for confirmatory adaptive designs. Confirmatory adaptive designs are a generalization of group sequential designs. With these designs, interim analyses are performed in order to stop the trial prematurely under control of the Type I error rate. In adaptive designs, it is also permissible to perform a data-driven ... Read more

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  • Structure-Based Mechanics of Tissues and Organs

    Series series Biomedical and Life Sciences (R0)
    This book portrays the commonality of tissue micro-structure that dictates physiological function in various organs (microstructure-function relation). Tissue and organ models are used to illustrate physiological functions based on microstructure. Fiber scale properties such as orientation and crimp are described in detail. Structurally-based constitutive models are given throughout the book, not ... Read more

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  • The Anticipation of Converging Industries

    A Concept Applied to Nutraceuticals and Functional Foods

    Series series Engineering (R0)
    The blurring of boundaries between hitherto distinct scientific disciplines, technologies or markets is a common and powerful phenomenon. Subjects of this convergence often change consumer behaviours, favouring products and platforms with multiple functions. The Anticipation of Converging Industries provides a detailed focus on the triggers, drivers and consequences of convergence to create a more ... Read more

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  • Computational Methods in Systems Biology

    13th International Conference, CMSB 2015, Nantes, France, September 16-18, 2015, Proceedings

    Series series Springer Nature Proceedings Computer Science
    This book constitutes the refereed proceedings of the 13th International Conference on Computational Methods in Systems Biology, CMSB 2015, held in Nantes, France, in September 2015. The 20 full papers and 2 short papers presented were carefully reviewed and selected from 43 full and 4 short paper submissions. The papers cover a wide range of topics in the analysis of biological systems, networks ... Read more

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  • Hybrid Systems Biology

    5th International Workshop, HSB 2016, Grenoble, France, October 20-21, 2016, Proceedings

    Series series Springer Nature Proceedings Computer Science
    This book constitutes the refereed proceedings of the 5th International Workshop on Hybrid Systems Biology, HSB 2016, held in Grenoble, France, in October 2016.The 11 full papers presented in this book were carefully reviewed and selected from 26 submissions. They were organized and presented in 4 thematic sessions also reflected in this book: model simulation; model analysis; discrete and network ... Read more

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  • Signposts to Chiral Drugs

    Organic Synthesis in Action

    Series series Biomedical and Life Sciences (R0)
    Highlighting 15 selected chiral structures, which represent candidate or marketed drugs, and their chemical syntheses, the authors acquaint the reader with the fascinating achievements of synthetic and medicinal chemistry.The book starts with an introduction treating the discovery and development of a new drug entity. Each of the 15 subsequent chapters presents one of the target structures and ... Read more

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  • Modelling and Simulation of Diffusive Processes

    Methods and Applications

    Edited by S.K. Basu, Naveen Kumar ...
    Series series Computer Science (R0)
    This book addresses the key issues in the modeling and simulation of diffusive processes from a wide spectrum of different applications across a broad range of disciplines. Features: discusses diffusion and molecular transport in living cells and suspended sediment in open channels; examines the modeling of peristaltic transport of nanofluids, and isotachophoretic separation of ionic samples in ... Read more

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  • Guide to Simulation-Based Disciplines

    Advancing Our Computational Future

    Series series Computer Science (R0)
    This invaluable text/reference reviews the state of the art in simulation-based approaches across a wide range of different disciplines, and provides evidence of using simulation-based approaches to advance these disciplines. Highlighting the benefits that simulation can bring to any field, the volume presents case studies by the leading experts from such diverse domains as the life sciences, ... Read more

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