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  • Cell Signaling During Mammalian Early Embryo Development

    Series series Biomedical and Life Sciences (R0)
    The book considers signaling events from the zygote embryo through to the blastocyst with relevant data from embryonic stem (ES) cells, including dialogue with the extracellular environment and with the maternal tract during the implantation process. Application of the knowledge described to improve the success of human and animal assisted conception is considered where appropriate, but the focus ... Read more

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    Series series Biomedical and Life Sciences (R0)
    This book describes human development including sexual reproduction and stem cell research with the development of model organisms that are accessible to genetic and experimental analysis in readily understandable texts and 315 multi-colored graphics. The introductory account of model organisms selected from the entire animal kingdom presents general principles, which are then outlined in ... Read more

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  • Pluripotency in Domestic Animal Cells

    Series series Biomedical and Life Sciences (R0)
    This addition to the Springer Brief in Stem Cells series focuses on aspects related to the specific mechanisms that ensure and control pluripotency and cell commitment in domestic animal species. This topic is generating rapidly-increasing interest due to the great potential for domestic animal species to be used as intermediate biomedical models, between the mouse and the human. The Brief ... Read more

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  • Gamete and Embryo Selection

    Genomics, Metabolomics and Morphological Assessment

    Series series Biomedical and Life Sciences (R0)
    This book provides the Assisted Reproduction Technologies (ART) community an update of the fast approaching novel technologies that may allow improved assessment of the reproductive potential of sperm, oocytes and embryos. The reader has access to concise updates on the rapidly developing diagnostic technologies (genomics, transcriptomics, proteomics and metabolomics) and morphological methods ... Read more

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  • Sperm Chromatin

    Biological and Clinical Applications in Male Infertility and Assisted Reproduction

    Edited by Armand Zini, Ashok Agarwal ...
    Series series Medicine (R0)
    Sperm DNA damage is common and has been associated with reduced rates of conception, impaired embryonic development and increased risk of miscarriage. Although the exact causes of sperm DNA damage are unknown, it is clear that infertile men possess substantially higher levels of sperm DNA damage than do fertile men. Written by leading, internationally renowned clinicians and basic scientists with ... Read more

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  • Testosterone: From Basic Research to Clinical Applications

    Series series Biomedical and Life Sciences (R0)
    This volume provides a brief résumé of the history of testosterone research, from the early pioneers through to the most recent advances in the field. We discover how steroid hormones were first identified and how testosterone was shown to be essential for male development. Moving forward we explore how and where testosterone is produced, and how the body controls testosterone production. We then ... Read more

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  • Molecular Mechanisms of Cell Differentiation in Gonad Development

    Edited by Rafal P. Piprek ...
    Series Book 58 - Results and Problems in Cell Differentiation
    This book presents the current state of knowledge on the origin and differentiation of cell lines involved in the development of the vertebrate male and female gonads with particular emphasis on the mouse. It also discusses the processes leading to the testis- and ovary-specific structures and functions.The individual chapters review the origin and differentiation of the somatic cells of the ... Read more

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  • Male Infertility

    Contemporary Clinical Approaches, Andrology, ART & Antioxidants

    Series series Medicine (R0)
    A ground-breaking contribution to the literature, Male Infertility: Contemporary Clinical Approaches, Andrology, ART & Antioxidants offers a comprehensive review of well-established, current diagnostic and treatment techniques for male infertility. This state-of-the-art, evidence-based resource incorporates new multidisciplinary and complementary medicine approaches to create a first-of-its-kind ... Read more

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  • Oocyte Biology in Fertility Preservation

    Edited by S. Samuel Kim ...
    Series series Biomedical and Life Sciences (R0)
    Fertility preservation has become one of the most important and fast growing fields of reproductive medicine. Although there are several strategies for fertility preservation in female, most of them are still considered experimental. It is important to perfect the existing technologies, but also developing new strategies should be actively sought. The future development of fertility preservation ... Read more

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  • Advances in Fetal and Neonatal Physiology

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    Edited by Lubo Zhang, Charles A. Ducsay ...
    Series series Springer Nature Proceedings excluding Computer Science
    To celebrate the Center for Perinatal Biology’s 40th Anniversary, an illustrious group gathered at Loma Linda University in February 2013. That gathering of experts and this volume of the proceedings are a tribute to the founder of the Center, Lawrence D. Longo, M.D. These chapters present contributions from individuals who in some way or another were influenced by Dr. Longo. Covering a wide range ... Read more

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  • Oxidative Stress in Human Reproduction

    Shedding Light on a Complicated Phenomenon

    Series series Medicine (R0)
    This book discusses the role of oxidative stress in the reproductive system. The book reviews endogenous sources, methods of determining its levels in body fluid/tissues, the physiological roles of ROS, as well as its negative effects on the human reproductive processes. Also discussed are multiple extrinsic factors that could induce oxidative stress in the reproductive system. This volume covers ... Read more

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  • The Male Role in Pregnancy Loss and Embryo Implantation Failure

    Edited by Richard Bronson ...
    Series series Biomedical and Life Sciences (R0)
    Novel topics compiled in this one-of-a-kind volume provide tantalizing hints for clinical application through future translational research. Only recently have we come to ask what role the male might play in pregnancy loss and embryo implantation failure, beyond contributing an abnormal set of paternal chromosomes at fertilization. This volume explores the recent evidence that these conditions ... Read more

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