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  • Statistical Analysis of Next Generation Sequencing Data

    Edited by Somnath Datta, Dan Nettleton ...
    Series series Frontiers in Probability and the Statistical Sciences
    Next Generation Sequencing (NGS) is the latest high throughput technology to revolutionize genomic research. NGS generates massive genomic datasets that play a key role in the big data phenomenon that surrounds us today. To extract signals from high-dimensional NGS data and make valid statistical inferences and predictions, novel data analytic and statistical techniques are needed. This book ... Read more

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  • Statistics in Medicine

    Statistics in Medicine, Third Edition makes medical statistics easy to understand by students, practicing physicians, and researchers. The book begins with databases from clinical medicine and uses such data to give multiple worked-out illustrations of every method. The text opens with how to plan studies from conception to publication and what to do with your data, and follows with step-by-step ... Read more

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  • Basics of Bioinformatics

    Lecture Notes of the Graduate Summer School on Bioinformatics of China

    Series series Computer Science (R0)
    This book outlines 11 courses and 15 research topics in bioinformatics, based on curriculums and talks in a graduate summer school on bioinformatics that was held in Tsinghua University. The courses include: Basics for Bioinformatics, Basic Statistics for Bioinformatics, Topics in Computational Genomics, Statistical Methods in Bioinformatics, Algorithms in Computational Biology, Multivariate ... Read more

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  • Primer to Analysis of Genomic Data Using R

    by Cedric Gondro ...
    Series series Mathematics and Statistics (R0)
    Through this book, researchers and students will learn to use R for analysis of large-scale genomic data and how to create routines to automate analytical steps. The philosophy behind the book is to start with real world raw datasets and perform all the analytical steps needed to reach final results. Though theory plays an important role, this is a practical book for graduate and undergraduate ... Read more

    $58.49 USD

  • Introduction to Nonparametric Statistics for the Biological Sciences Using R

    Series series Mathematics and Statistics (R0)
    This book contains a rich set of tools for nonparametric analyses, and the purpose of this text is to provide guidance to students and professional researchers on how R is used for nonparametric data analysis in the biological sciences:To introduce when nonparametric approaches to data analysis are appropriateTo introduce the leading nonparametric tests commonly used in biostatistics and how R is ... Read more

    $62.99 USD

  • Permutation Testing for Isotonic Inference on Association Studies in Genetics

    Series series Mathematics and Statistics (R0)
    The purpose of this book is to illustrate a new statistical approach to test allelic association and genotype-specific effects in the genetic study of diseases. There are some parametric and non-parametric methods available for this purpose. We deal with population-based association studies, but comparisons with other methods will also be drawn, analysing the advantages and disadvantages of each ... Read more

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  • Design, Analysis, and Interpretation of Genome-Wide Association Scans

    Series series Mathematics and Statistics (R0)
    This book presents the statistical aspects of designing, analyzing and interpreting the results of genome-wide association scans (GWAS studies) for genetic causes of disease using unrelated subjects. Particular detail is given to the practical aspects of employing the bioinformatics and data handling methods necessary to prepare data for statistical analysis. The goal in writing this book is to ... Read more

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  • Epigenetics and Complex Traits

    Series series Biomedical and Life Sciences (R0)
    This book will provide an overview of basic epigenetic phenomena; interaction between epigenetic and genetic factors; and the influence of epigenetic factors on inheritance. Epigenetic states may contribute to the penetrance of genetic polymorphisms or mutations and thereby modify inheritance patterns. This may result in non‐Mendelian inheritance of genetic traits such as observed in common human ... Read more

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  • Recent Progress in the Genetic Epidemiology of Cancer

    Edited by Henry T. Lynch, Petre Tautu ...
    The discipline of genetic epidemiology pertains to the vertical transmission of the susceptibility (predisposition) to a complex disease in a structured population. This statement meets halfway 1 the broad definitiongiven by N. E. Morton and S. c. Chung in 1978 2 and the concise one given by M. -C. King et al. in 1984. 1t pinpoints the fundamental genetic hypothesis, namely, the existence of an ... Read more

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  • The Fundamentals of Modern Statistical Genetics

    Series series Mathematics and Statistics (R0)
    This book covers the statistical models and methods that are used to understand human genetics, following the historical and recent developments of human genetics. Starting with Mendel’s first experiments to genome-wide association studies, the book describes how genetic information can be incorporated into statistical models to discover disease genes. All commonly used approaches in statistical ... Read more

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  • Evolutionary Bioinformatics

    Series series Biomedical and Life Sciences (R0)
    Now in its third edition and supplemented with more online material, this book aims to make the "new" information-based (rather than gene-based) bioinformatics intelligible both to the "bio" people and the "info" people. Books on bioinformatics have traditionally served gene-hunters, and biologists who wish to construct family trees showing tidy lines of descent. While dealing extensively with the ... Read more

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  • Assessing Rare Variation in Complex Traits

    Design and Analysis of Genetic Studies

    This book is unique in covering a wide range of design and analysis issues in genetic studies of rare variants, taking advantage of collaboration of the editors with many experts in the field through large-scale international consortia including the UK10K Project, GO-T2D and T2D-GENES. Chapters provide details of state-of-the-art methodology for rare variant detection and calling, imputation and ... Read more

    $143.09 USD