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  • Mitochondrial Dynamics and Neurodegeneration

    Edited by Bingwei Lu ...
    Series series Biomedical and Life Sciences (R0)
    Mitochondria are essential organelles in eukaryotic cells that control such diverse processes as energy metabolism, calcium buffering, and cell death. Recent studies have revealed that changes in mitochondrial morphology by fission and fusion, a process known as mitochondrial dynamics, is particularly important for neuronal function and survival. Defects in this process are commonly found in ... Read more

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    Daily rhythms are a ubiquitous feature of living systems. Generally, these rhythms are not just passive consequences of cyclic fluctuations in the environment, but instead originate within the organism. In mammals, including humans, the master pacemaker controlling 24-hour rhythms is localized in the suprachiasmatic nuclei of the hypothalamus (SCN). This circadian clock is responsible for the ... Read more

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  • Sensory Neuroscience: Four Laws of Psychophysics

    Sensory Neuroscience: Four Laws of Psychophysics organizes part of psychophysics -- a science of quantitative relationships between human sensations and the stimuli that evoke them. Although psychophysics belongs to sensory neuroscience, and is coupled to neurophysiology, it has also branched out to various specialized disciplines, including the disciplines of vision and hearing, ophthalmology, ... Read more

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    These past few years have witnessed a revolution in our understanding of microglia, especially since their roles in the healthy central nervous system (CNS) have started to unravel. These cells were shown to actively maintain health, in concert with neurons and other types of CNS cells, providing further insight into their involvement with diseases. Edited by two pioneers in the field, Marie-Ève ... Read more

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    A thorough introduction is provided to the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic information as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during ... Read more

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