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  • Ageing: Lessons from C. elegans

    Edited by Anders Olsen, Matthew S. Gill ...
    Series series Biomedical and Life Sciences (R0)
    This book brings together in one volume the current state of ageing research in the nematode Caenorhabditis elegans. The authors are leading researchers in the field, placing this topic in the context of human ageing, describing how and why basic discoveries in this simple organism have impacted our prospects for intervention in the ageing process. The authors cover a broad range of topics with ... Read more

    $107.09 USD

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  • Semaphorins

    A Diversity of Emerging Physiological and Pathological Activities

    Edited by Atsushi Kumanogoh ...
    Series series Biomedical and Life Sciences (R0)
    This book presents the current concepts of semaphorin biology. In the early 1990s, semaphorins were originally identified as axon guidance cues that function during neuronal development. However, cumulative findings have clarified that they have diverse functions in many physiological processes, including cardiogenesis, angiogenesis, vasculogenesis, osteoclastogenesis, retinal homeostasis, and ... Read more

    $89.09 USD

  • microRNA: Medical Evidence

    From Molecular Biology to Clinical Practice

    Edited by Gaetano Santulli ...
    Series series Biomedical and Life Sciences (R0)
    This volume explores microRNA function in a wide array of human disorders, providing a clinical basis for precision medicine and personalized therapies using these molecules. The twenty-one chapters, all authored by internationally-renowned experts, open with an introduction contextualizing microRNA manipulation within today’s initiatives towards precision medicine. The following chapters explore ... Read more

    $143.09 USD

  • microRNA: Cancer

    From Molecular Biology to Clinical Practice

    Edited by Gaetano Santulli ...
    Series series Biomedical and Life Sciences (R0)
    This volume thoroughly explores of the functional role of microRNAs in cancer. It not only expertly describes the molecular mechanisms underlying the malignant transformation process but also compiles cutting-edge research on microRNAs in several forms of cancer, including colorectal cancer, pancreatic cancer, leukemia/lymphoma, prostate cancer, lung cancer, ovarian cancer, and bone cancer. ... Read more

    $89.09 USD

  • Folding for the Synapse

    Folding for the Synapse addresses the current view on how protein folding and misfolding, controlled by molecular chaperones, contribute to synapse function and dysfunction. Molecular chaperones have been studied in relation to de novo protein folding, but there is increasing awareness that chaperone function is required for the regulation of protein dynamics when functioning physiologically as an ... Read more

    $188.99 USD

  • Perspectives in Translational Research in Life Sciences and Biomedicine

    Translational Outcomes Research in Life Sciences and Translational Medicine, Volume 1

    Series series Biomedical and Life Sciences (R0)
    The present book addresses the multi-disciplinary nature of Translational Outcomes Research, which is a watershed for nearly all the disciplines of Life and Health Sciences, along with the Materials Sciences including but not limited to Zoology, Botany, Microbiology, Biochemistry, Physiology, Nanotechnology, the Medical Sciences, Bioengineering, Biophysics, Medicinal Chemistry, Structural Biology, ... Read more

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  • microRNA: Basic Science

    From Molecular Biology to Clinical Practice

    Edited by Gaetano Santulli ...
    Series series Biomedical and Life Sciences (R0)
    This volume explores microRNA pathophysiology, focusing on basic concepts in molecular and cellular biology. Chapters contributed by leading scientists examine recently discovered pathways in several processes, including aging, diabetes, cardiovascular disease, hematopoiesis, and mitochondrial fitness. The authors contextualize microRNAs within epigenetics and micropeptidomics, angiongenesis and ... Read more

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  • Molecularly Targeted Therapy for Childhood Cancer

    Series series Biomedical and Life Sciences (R0)
    Each chapter will focus on the known molecular characteristics of specific childhood cancers, focusing on how the molecular ‘drivers’ can be exploited from a therapeutic standpoint with currently available targeted agents. Where applicable, integration of targeted therapies with conventional cytotoxic agents will be considered.This volume will provide a comprehensive summary of molecular ... Read more

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  • The Biology of Subcellular Nitric Oxide

    Series series Biomedical and Life Sciences (R0)
    This book fills in a gap in the NO literature. Recent progress in the field of NO-biology shows that NO is generated within distinct cell compartments, including specific plasma membrane regions, mitochondria, chloroplasts, peroxisomes, the Golgi-complex and intracellular membrane systems. NO synthesis plays specific roles in these compartments and, in turn, cell organelles also control ... Read more

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  • Modeling Fragile X Syndrome

    Edited by Robert B. Denman ...
    Series series Biomedical and Life Sciences (R0)
    Introduction.-Probing Astrocyte Function in Fragile X Syndrome.- Neural Stem Cells.- Fragile X Mental Retardation Protein (FMRP) and the Spinal Sensory System.– The Role of the Postsynaptic Density in the Pathology of the Fragile X Syndrome.- Behavior in a Drosophila model of Fragile X.- Molecular and Genetic Analysis of the Drosophila Model of Fragile X Syndrome.- Fragile X Mental Retardation ... Read more

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  • Blue Biotechnology

    From Gene to Bioactive Product

    Series series Biomedical and Life Sciences (R0)
    This book describes the discovery of molecules from unexploited extreme marine environments, and presents new approaches in marine genomics. It combines the current state of knowledge in marine genomics and advanced natural products’ chemistry to pursue the sustainable production of novel secondary metabolites (lead compounds), as well as pharmacologically active peptides/proteins, with ... Read more

    $170.99 USD

  • Nuclear Receptors

    Current Concepts and Future Challenges

    Series series Biomedical and Life Sciences (R0)
    In 1890 a case of myxedema was treated in Lisbon by the implantation of a sheep thyroid gland with the immediate improvement in the patient’s condition. A few years later, medications for the then ill-explained condition of the menopause included tablets made from cow ovaries. In the first quarter of the 20th century the identification of vitamin D, and its sunlight driven production in skin, ... Read more

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